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Search Results for " glyceraldehyde "

11

抑制剂 & 化合物

2

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T78360	Glyceraldehyde phosphate dehydrogenase GAPDH,G3PDH,GADPH
	Glyceraldehyde phosphate dehydrogenase是一种酶，既是抗胸腺细胞剂也是抗凋亡剂的靶点，它负责催化过羟基自由基对还原型烟酰胺腺嘌呤二核苷酸（NADH）的链氧化反应。
T37521	DL-Glyceraldehyde 3-phosphate 3-Phosphoglyceraldehyde,DL-甘油醛3-磷酸
	DL-Glyceraldehyde-3-phosphate (GADP) is an intermediate in several metabolic pathways, including glycolysis and gluconeogenesis. In glycolysis, it can be derived from fructose 1,6-bisphosphate by fructose bisphosphate aldolase in a reaction that also produces dihydroxyacetone phosphate (DHAP). Triose phosphate isomerase reversibly converts DHAP to GADP. GADP is processed to 1,3-bisphosphoglycerate by glyceraldehyde phosphate dehydrogenase and NAD+.
T74941	D-Glyceraldehyde 3-phosphate
	D-Glyceraldehyde 3-phosphate (Triose phosphate) 是一种在生物体内广泛存在的分子，主要作为糖酵解过程和糖异生过程的关键中间体，同时也是卡尔文循环生成糖类的产物。此外，D-Glyceraldehyde 3-phosphate 还涉及色氨酸和硫胺素的生物合成过程。
T35317	Zopolrestat CP 73850,CP73850,CP-73850,唑泊司他,Zopolrestatum	Reductase	Endocrinology/Hormones; Metabolism
	Zopolrestat (CP 73850) 是口服有效的醛糖还原酶抑制剂，IC50为3.1 nM。Zopolrestat (CP 73850) 在糖尿病并发症方面有研究的价值。
T77332	TV 3279	BCL; PKC	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling
	TV 3279是一种新型ChE-MAI 抑制剂，神经保护特性取决于它们诱导抗凋亡蛋白PKC、Bcl-2、Bcl-x 和SOD 的能力，并阻止促凋亡酶甘油醛磷酸脱氢酶在PC-12和神经母细胞瘤细胞中的核易位。
T76154	Triosephosphate isomerase
	Triosephosphate isomerase (TPI) 是一种能够在糖酵解过程中快速转换磷酸二羟丙酮(dihydroxyacetone phosphate)与D: -甘油醛-3-磷酸(D: -glyceraldehyde-3-phosphate)的酶。其催化位点位于酶的二聚体界面。
T72879	Misetionamide
	Misetionamide，一种恶噻嗪类口服化合物，作为甘油醛-3-磷酸脱氢酶 (GAPDH) 抑制剂，展现出抗肿瘤活性，适用于癌症研究。
T80931	Tri-valine NSC 35938
	Tri-valine (NSC 35938) 为多肽类化合物，可从肌酸激酶 (Creatine kinase)、β-烯醇化酶、三磷酸异构酶 (Triosephosphate isomerase) 及甘油醛 3-磷酸脱氢酶中分离得到。
T37989	D-Sedoheptulose-7-phosphate (barium salt)
	D-Sedoheptulose-7-phosphate is an intermediate in the pentose phosphate pathway. [1] [2] In this pathway, transaldolase catalyzes the transfer of a three carbon dihydroxyacetone moiety from D-sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate to generate D-fructose-6-phosphate . D-Sedoheptulose-7-phosphate is also an intermediate in carbon fixation in photosynthetic organisms, as well as in the biosynthesis of lipopolysaccharide, amino acids, secondary metabolites, and antibiotics. [3]
T10966	DC-5163	Others	Others
	DC-5163 is a potent inhibitor of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with IC50 of 176.3 nM and Kd of 3.192 μM. DC-5163 selectively inhibits cancer cell proliferation and induces apoptosis, and partially inhibits the glycolysis pathway.
T76097	Aldolase
	Aldolase 是一种糖酵解酶，也是 vATP 酶复合物的组成部分。Aldolase 可使 1，6-二磷酸果糖分解成二羟基丙酮和 3-磷酸甘油醛。

化合物

Glyceraldehyde phosphate dehydrogenase

Cat.No: T78360

Synonym: GAPDH,G3PDH,GADPH

DL-Glyceraldehyde 3-phosphate

Cat.No: T37521

Synonym: 3-Phosphoglyceraldehyde,DL-甘油醛3-磷酸

D-Glyceraldehyde 3-phosphate

Cat.No: T74941

Cat.No: T35317

Synonym: CP 73850,CP73850,CP-73850,唑泊司他,Zopolrestatum

Target: Reductase

Cat.No: T77332

Target: BCL, PKC

Triosephosphate isomerase

Cat.No: T76154

Cat.No: T72879

Cat.No: T80931

Synonym: NSC 35938

D-Sedoheptulose-7-phosphate (barium salt)

Cat.No: T37989

Cat.No: T10966

Target: Others

Cat.No: T76097

Cat. No.	Product Name	Target	Signaling Pathways
T4918	DL-Glyceraldehyde Glyceric aldehyde,DL-甘油醛晶体	Reductase	Endocrinology/Hormones; Metabolism
	DL-Glyceraldehyde (Glyceric aldehyde) 是由酶甘油醛脱氢酶的作用产生的，该酶使用 NADP 作为辅因子将甘油转化为甘油醛。它是一种高活性化合物，可以修饰和交联蛋白质。
TN4578	Monomethyl kolavate	Antifection	Microbiology/Virology
	Monomethyl kolavate is a power Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) inhibitor, with an IC50 value of 12uM.

天然产物

DL-Glyceraldehyde

Cat.No: T4918

Synonym: Glyceric aldehyde,DL-甘油醛晶体

Target: Reductase

Monomethyl kolavate

Cat.No: TN4578

Target: Antifection

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