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Cat. No. Product Name Target Signaling Pathways
T8674 SR33805

Calcium Channel Membrane transporter/Ion channel; Metabolism
SR33805 是钙通道拮抗剂,在去极化和极化条件下的 EC50值分别为 4.1 和 33 nM。它阻止 L 型 Ca2+通道,可用于研究急性或慢性心脏衰竭。
T26822 Bisaramil hydrochloride

RGH-2957,NK 1556,NK1556,Bisaramil,NK-1556,RGH 2957

Potassium Channel; Adrenergic Receptor GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
Bisaramil hydrochloride (Bisaramil) 是一种新型二氮双环壬烷抗心律失常化合物,抑制自由基生成。Bisaramil hydrochloride 可阻断钠电流,抑制异丙肾上腺素在 K(+) 去极化肌上诱导的缓慢 Ca(2+) 动作电位。
TP1531 Guangxitoxin 1E

Guangxitoxin 1E acts as a gating modifier since it shifts the voltage-dependence of Kv2.1 K+ currents towards depolarized potentials.
T68499 F15845 HBr

F 15845 is a blocker of the persistent sodium current prevents consequences of hypoxia in rat femoral artery. F15845 has been shown to selectively inhibit the persistent sodium current of Nav1.5[1] exerting cardioprotective effects following ischemia. In vitro testing showed minimal effects of F15845 on other important ion channels of the heart, including major Ca2+ and K+ channels.[1] This characteristic is thought to account for the limited effect of F15845 to change other heart parameters suc...
T71402 Nicorandil-d4

Nicorandil-d4 is intended for use as an internal standard for the quantification of nicorandil by GC- or LC-MS. Nicorandil is an activator of sulfonylurea receptor 2B (SUR2B) linked to ATP-sensitive potassium channel Kir6.2 (EC50 = ~10 µM) and a nitric oxide (NO) donor. It is selective for SUR2B/Kir6.2 over the SUR2A/Kir6.2 channel (EC50 = >500 µM). Nicorandil activates soluble guanylate cyclase in a cell-free assay and relaxes partially depolarized isolated bovine coronary artery strips (EC50 =...

化合物

SR33805
Cat.No: T8674
Synonym:
Target: Calcium Channel
Bisaramil hydrochloride
Cat.No: T26822
Synonym: RGH-2957,NK 1556,NK1556,Bisaramil,NK-1556,RGH 2957
Target: Potassium Channel, Adrenergic Receptor
Guangxitoxin 1E
Cat.No: TP1531
Synonym:
Target:
F15845 HBr
Cat.No: T68499
Synonym:
Target:
Nicorandil-d4
Cat.No: T71402
Synonym:
Target:
TargetMol Loading
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