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6

抑制剂 & 化合物

1

天然产物

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Cat. No. Product Name Target Signaling Pathways
T1006 Propantheline bromide

Neopepulsan,溴丙胺太林,Pro-Banthine,Neometantyl

AChR Neuroscience
Propantheline bromide (Pro-Banthine) 是一种抗毒蕈碱剂,用于研究多汗症,遗尿,胃肠和膀胱痉挛。
T0786 Clidinium bromide

克利溴铵,Ro 2-3773

AChR Neuroscience
Clidinium bromide (Ro 2-3773) 是季胺抗毒蕈碱剂,可通过减少胃酸和减慢肠道速度,缓解痉挛和腹部疼痛的症状。
T33314 Methantheline Bromide

Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide

Methantheline Bromide is a synthetic spasmolytic used to relieve cramps or spasms of the stomach, bowel, and bladder. It is also useful for intestinal or gastric ulcers (peptic ulcer disease), intestinal problems, pancreatitis, gastritis, biliary dysmotil
T61453 Propantheline

Propantheline is an orally active antagonist of muscarinic acetylcholine receptors (mAChRs), commonly employed to investigate smooth muscle dysfunction, hyperhidrosis, smooth muscle spasms or cramps in the stomach, intestines, or bladder, as well as involuntary urination [1] [2] [3].
T70153 Pipoxolan hydrochloride

Pipoxolan (HCl) is an antispasmodic drug. In vivo, the drug inhibited the contractions of intestines caused by neostigmine, barium chloride or injection of acetylcholine. The drug possesses ganglioplegic action and inhibited the decrease in blood pressure caused by stimulation of the vagus nerve. The drug is marketed under tradename Rowapraxin worldwide for the treatment of spasms and colics in the gastrointestinal tract, gallbladder and urogenital area, bronchial spasms, spastic menstrual cramp...
T69661 Pipoxolan (free base)

Pipoxolan (free base) is an antispasmodic drug. In vivo, the drug inhibited the contractions of intestines caused by neostigmine, barium chloride or injection of acetylcholine. The drug possesses ganglioplegic action and inhibited the decrease in blood pressure caused by stimulation of the vagus nerve. The drug is marketed under tradename Rowapraxin worldwide for the treatment of spasms and colics in the gastrointestinal tract, gallbladder and urogenital area, bronchial spasms, spastic menstrual...

化合物

Propantheline bromide
Cat.No: T1006
Synonym: Neopepulsan,溴丙胺太林,Pro-Banthine,Neometantyl
Target: AChR
Clidinium bromide
Cat.No: T0786
Synonym: 克利溴铵,Ro 2-3773
Target: AChR
Methantheline Bromide
Cat.No: T33314
Synonym: Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide
Target:
Propantheline
Cat.No: T61453
Synonym:
Target:
Pipoxolan hydrochloride
Cat.No: T70153
Synonym:
Target:
Pipoxolan (free base)
Cat.No: T69661
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T0690 Quinine

奎宁树

Potassium Channel; Platelet aggregation; Parasite Membrane transporter/Ion channel; Microbiology/Virology; Others
Quinine 是一种从金鸡纳树皮中提取的生物碱,用于预防和治疗疟疾。它也用于特发性肌肉痉挛,可抑制电压脉冲引起的 MT mSlo3 (KCa5.1) 通道 +100 mV 电流, 其IC50值为 169 μM,是一种钾离子通道抑制剂。

天然产物

Quinine
Cat.No: T0690
Synonym: 奎宁树
Target: Potassium Channel, Platelet aggregation, Parasite
TargetMol Loading
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