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Cat. No. Product Name Target Signaling Pathways
T1564 Cisplatin

cis-Diaminodichloroplatinum,CDDP,顺铂

DNA Alkylator/Crosslinker; Ferroptosis; DNA/RNA Synthesis; Autophagy Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Cisplatin (CDDP) 是一种 DNA 交联剂。Cisplatin 具有抗肿瘤活性,能够通过在癌细胞中形成 DNA 加合物来抑制 DNA 合成。Cisplatin 还可激活铁死亡并诱导自噬。
T28398 Phenanthriplatin

cis-[Pt(NH3)2-(phenanthridine)Cl]NO3

Phenanthriplatin, also known as cis-[Pt(NH3)2-(phenanthridine)Cl]NO3, is a new drug candidate. It belongs to a family of platinum(II)-based agents which includes cisplatin, oxaliplatin and carboplatin. Phenanthriplatin Acts As a Covalent Poison of Topoiso
T36745 cDPCP

cDPCP is a platinum-containing DNA-crosslinking agent.1Unlike cisplatin or oxaliplatin , cDPCP forms monofunctional DNA adducts. It is transported into cells by organic cation transporter 1 (OCT1) and OCT2, inhibiting proliferation of MDCK cells expressing the human transporters with IC50values of 8.1 and 1.5 μM, respectively. cDPCP inhibits RNA polymerase II-mediated transcription in a reporter assay using HeLa cells. It increases survival in murine S180 sarcoma and P388 leukemia models when ad...

化合物

Cisplatin
Cat.No: T1564
Synonym: cis-Diaminodichloroplatinum,CDDP,顺铂
Target: DNA Alkylator/Crosslinker, Ferroptosis, DNA/RNA Synthesis, Autophagy
Phenanthriplatin
Cat.No: T28398
Synonym: cis-[Pt(NH3)2-(phenanthridine)Cl]NO3
Target:
cDPCP
Cat.No: T36745
Synonym:
Target:
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