Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T82733 |
Cholecystokinin
CCK-33(human),Cholecystokinin-33(human) |
||
Cholecystokinin是一种通过抑制食物摄入并促进脂肪及蛋白质消化作用的肽类激素,常用于胃肠系统研究。 | |||
TP2500 |
Cholecystokinin (26-33) free acid
CCK (26-33) free acid |
cholecystokinin | GPCR/G Protein |
Cholecystokinin (26-33) free acid 是胆囊收缩素 (CCK) 的一部分, 是脊椎动物中枢神经系统中存在的 CCKB 型受体的高选择性配体,可诱导大鼠轻度味觉厌恶条件反射。 | |||
TP2419 |
V-9-M Cholecystokinin nonapeptide
V 9 M,Prepro CCK Fragment V-9-M,Val-pro-val-glu-ala-val-asp-pro-met,Cholecystokinin Precursor (24-32),V9M,V-9-M |
Beta Amyloid | Neuroscience |
V-9-M Cholecystokinin nonapeptide (Prepro CCK Fragment V-9-M) 是胆囊收缩素(CCK)的前体化合物。胆囊收缩素(CCK)是一种刺激胆囊收缩和胰腺外分泌的脑肠肽,可从狗和猫的小肠中提取的,可以引起胆囊收缩。 | |||
TP1198 |
Sincalide ammonium
SQ19844 ammonium,CCK-8 ammonium,Cholecystokinin octapeptide ammonium |
cholecystokinin | GPCR/G Protein |
Sincalide ammonium (CCK-8 ammonium) 是一种有效的氨基酸多肽激素胆囊收缩素 (CCK) 的类似物,是保留了 CCK 的大部分生物活性的活性片段。Sincalide ammonium 促进胆汁的分泌,使胆囊收缩并使 Oddi 的括约肌松弛,从而促进胆汁排入十二指肠。Sincalide ammonium 可通过注射促进胆囊收缩,常用于辅助诊断胆囊、胰腺疾病和胆囊造影术。 | |||
T39170 |
Cholecystokinin Octapeptide, desulfated TFA
CCK Octapeptide, desulfated TFA,Cholecystokinin Octapeptide, desulfated TFA |
||
Cholecystokinin Octapeptide, desulfated TFA, is a synthetic octapeptide derived from Cholecystokinin (CCK) that has undergone desulfation. | |||
T23886 |
Cholecystokinin (27-32)-amide
Cholecystokinin (27-32)-NH2 |
||
Cholecystokinin (27-32)-amide is a CCK receptor antagonist. | |||
TP1197 |
Sincalide
SQ19844,辛卡利特,CCK-8,Cholecystokinin octapeptide |
Others | Others |
Sincalide (CCK-8) 是一种速效的胆囊收缩素的氨基酸多肽激素类似物,可在胆囊造影术中静脉使用。它的肝胆生理作用是增加胆汁的分泌,使胆囊收缩并使 Oddi 的括约肌松弛,从而使胆汁排入十二指肠。它是一种通过注射促进胆囊收缩并帮助诊断胆囊和胰腺疾病的药物。 | |||
T30904 |
Cholecystokinin-J
CCK-J |
||
Cholecystokinin-J can be used in cholecystography, radiomanometry and biliary cinematography. | |||
TP2376 |
Cholecystokinin pentapeptide
CCK-5,Gly-trp-met-asp-phe-NH2 |
||
Cholecystokinin pentapeptide is a peptide hormone of the gastrointestinal system responsible for stimulating the digestion of fat and protein. | |||
TP2204 |
Cholecystokinin Octapeptide, desulfated
CCK Octapeptide, non-sulfated |
Others | Others |
Non-sulfated form of the C-terminal octapeptide of CCK | |||
T82732 |
Cholecystokinin (1-21)
CCK-1-21 |
||
Cholecystokinin (1-21),作为一种胆囊收缩素 (CCK) 片段,能够激活人体脂肪组织的脂肪分解作用。 | |||
T20492 |
Tetragastrin
Cholecystokinin tetrapeptide,Gastrin tetrapeptide |
||
Tetragastrin is the C-terminal tetrapeptide of gastrin. It has the same physiological and pharmacological activity as gastrin. | |||
T83485 |
[Thr28, Nle31]-Cholecystokinin (25-33), sulfated
|
||
[Thr28, Nle31]-Cholecystokinin (25-33) 是一种具备CCK8所有生物活性的胆囊收缩素 (CCK) 类似物,表现出食欲抑制功效。它在胃肠道系统和中枢神经系统中担任激素和神经递质角色。此肽通过 Thr28 和 Nle31 的特殊替代,展现出在酸性条件下的高稳定性,并能抵抗空气氧化(防止蛋氨酸受损)。其主要构象特征为以Thr4为核心的γ转角和Gly5分隔的C末端螺旋片段。 | |||
T2312 |
Loxiglumide
CR-1505,氯谷胺 |
cholecystokinin | GPCR/G Protein |
Loxiglumide (CR-1505) 是一种缩胆囊素受体拮抗剂。 | |||
TQ0062 |
Nastorazepide
Z-360 |
cholecystokinin | GPCR/G Protein |
Nastorazepide 是一种选择性的、口服有效的1,5-苯并二氮杂环衍生物胃泌素/胆囊收缩素2(CCK-2)受体拮抗剂,具有抗肿瘤的潜能。 | |||
T14932 |
Ceruletide
Cerulein,Caerulein,雨蛙素,FI-6934 |
cholecystokinin | GPCR/G Protein |
Ceruletide (Caerulein) 是一种十肽,是一种安全有效的胆囊收缩剂,是一种胆囊收缩素受体激动剂,对胆囊肌肉和胆管有直接的痉挛性作用。 | |||
T1052 |
Proglumide
二丙谷酰胺 |
cholecystokinin | GPCR/G Protein |
Proglumide (Binoside) 是一种非肽的、口服具有活性的胆囊收缩素(CCK)-A/B 受体拮抗剂。它能够选择性阻断 CCK 在中枢神经系统中的作用。它能够抑制胃分泌,具有保护胃十二指肠粘膜的能力,并表现出抗癫痫和抗氧化活性。 | |||
T4579 |
Pentagastrin
五肽胃泌素,ICI-50123 |
Others; cholecystokinin | GPCR/G Protein; Others |
Pentagastrin (ICI-50123) 是一种选择性的胆囊收缩素 B(CCKB) 受体激动剂,IC50=11 nM。它能够增强胃粘膜对酸的防御机制,并保护胃粘膜免受损伤。 | |||
TP2204L |
CCK Octapeptide, non-sulfated acetate
CCK Octapeptide, non-sulfated acetate(25679-24-7 Free base) |
cholecystokinin | GPCR/G Protein |
CCK Octapeptide, non-sulfated acetate 是一种合成的胆囊收缩素脱硫酸肽。 | |||
T15382 |
GI 181771
|
cholecystokinin | GPCR/G Protein |
GI 181771 是胆囊收缩素 1 受体的激动剂。 GI 181771 可用于肥胖研究。 | |||
T27503 |
GV150013
GV 150013,GV-150013 |
cholecystokinin | GPCR/G Protein |
GV150013是一种 cholecystokinin-2 (CCK2)受体拮抗剂。 | |||
T9343 |
N-Cbz-DL-tryptophan
|
cholecystokinin | GPCR/G Protein |
N-Cbz-DL-tryptophan 是一种胆囊收缩素受体拮抗剂,可消除离体心脏对 CCK-8 的反应。 | |||
T34123 |
Pranazepide
FR120480,FK 480,FR-120480 |
cholecystokinin | GPCR/G Protein |
Pranazepide (FK 480) 是一种小分子胆囊收缩素受体拮抗剂,可用于研究消化系统疾病和胰腺炎。 | |||
T14932L1 |
Ceruletide Ammonium Salt
Caerulein Ammonium Salt,Ceruletide Ammonium Salt(17650-98-5 Free base),FI-6934 Ammonium Salt,Cerulein Ammonium Salt |
cholecystokinin | GPCR/G Protein |
Ceruletide Ammonium Salt 是一种十肽,起源于热带青蛙的皮肤,是一种有效的胆囊收缩素受体 (cholecystokinin receptor) 激动剂,也是一种安全有效的胆囊收缩剂,对胆囊肌肉和胆管有直接的痉挛性作用。Ceruletide Ammonium Salt 具有镇静活性,可用于研究慢性精神分裂症。 | |||
TP2030L1 |
Gastrin I (human) acetate
Gastrin I (human) acetate(10047-33-3 free base),Gastrin-17 acetate,Little gastrin I acetate,胃膜素醋酸盐 |
cholecystokinin | GPCR/G Protein |
Gastrin I (human) acetate (Gastrin-17 acetate) 是在胃中产生的内源性肽,通过胆囊收缩素 2 (CCK2) 受体增加胃酸分泌。 | |||
T11868 |
Lorglumide sodium salt
CR-1409 sodium salt |
cholecystokinin | GPCR/G Protein |
Lorglumide sodium salt (CR-1409 sodium salt) 是胆囊收缩素受体 (CCK) 的拮抗剂。 | |||
T12404 |
CCK-A receptor inhibitor 1
|
cholecystokinin | GPCR/G Protein |
CCK-A receptor inhibitor 1 是一种有效的缩胆囊素 A (CCK-A) 受体抑制剂(IC50:340 nM)。CCK-A receptor inhibitor 1 可用于研究与消化系统相关的疾病。 | |||
T25116 |
Asperlicin D
AsperlicinD,Asperlicin-D |
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Asperlicin D is a cholecystokinin antagonist agent. | |||
T26483 |
A-65186
A65186 |
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A 65186 is a Type A Cholecystokinin (CCK) receptor antagonist. | |||
T27664 |
JNJ-17156516
JNJ17156516,JNJ 17156516 |
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JNJ-17156516 is a potent, and selective cholecystokinin 1 receptor antagonist. | |||
T71277 |
Amiglumide
|
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Amiglumide is a non-peptide cholecystokinin antagonist. | |||
T32297 |
Jmv 180
Cck-jmv-180,Jmv-180,Jmv180 |
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Jmv 180, a CCK analog, can distinguish high-affinity cholecystokinin receptors from low-affinity cholecystokinin receptors. | |||
T25551 |
Jmv 236
Jmv236,t-Boc(nle(28,31))-cck (26-33),Jmv-236 |
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Jmv 236 is a cholecystokinin antagonist. | |||
T26971 | Ceclazepide | ||
Ceclazepide is an antagonist of cholecystokinin receptor. | |||
T15105 | Dexloxiglumide | Others | Others |
Dexloxiglumide, an active enantiomer of Loxiglumide, inhibits smooth muscle cell contractions induced by cholecystokinin-octapeptide (CCK-8). It is a selective antagonist of cholecystokinin type A (CCKA) receptors. | |||
T71408 |
A 68552
|
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A 68552 is a cholecystokinin agonist. | |||
T28613 |
RP73870
RP 73870,RP-73870 |
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RP73870 is a gastrin/cholecystokinin-B receptor antagonist and H2 receptor antagonist with potent anti-ulcer activity. | |||
T23185 |
Proglumide sodium
丙谷胺钠,Proglumide sodium salt |
Others | Others |
Non-selective cholecystokinin (CCK) antagonist | |||
T27669 |
JNJ-26070109
JNJ26070109 |
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JNJ-26070109, an antagonist of cholecystokinin CCK2 receptor, inhibits gastric acid secretion and prevents omeprazole-induced acid rebound in the rat. | |||
T24202 |
Jmv 167
Jmv-167,Jmv167 |
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Jmv 167 is an antagonist of the Cholecystokinin receptor. | |||
T24204 |
Jmv 179
Jmv-179,Jmv179 |
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Jmv 179 is an antagonist of the cholecystokinin receptor. | |||
T24293 |
L 368935
L-368935,L368,935,L-368,935,L 368,935,L368935 |
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L 368935 is an antagonist of the cholecystokinin receptor. | |||
T29502 |
A 70874
A-70874,A70874 |
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A70874 has high selectivity and potency for cholecystokinin (CCK) a receptor. | |||
T28335 |
PD 140376
PD-140376,PD140376 |
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PD 140376 is a highly selective antagonist radioligand for the cholecystokinin(B)-gastrin receptor in guinea pig gastric mucosa & cerebral cortex in the peripheral and central nervous systems. | |||
T10055 |
(Iso)-FK-480
CHEMBL333994 |
cholecystokinin | GPCR/G Protein |
(Iso)-FK-480 是一种新型可口服的胆囊收缩素 A(CCK-A)拮抗剂,可用于研究治疗慢性胰腺炎。 | |||
T28331 |
PD 136450
Cam1189,PD136450,Cam-1189,PD-136450,Cam 1189 |
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Cholecystokinin type B receptor antagonist PD-136,450 is a partial secretory agonist in the stomach and a full agonist in the pancreas of the rat. Gastrin (cholecystokinin type B (CCK-B)) receptor antagonists may help to elucidate the physiological role o | |||
T22895 |
L-365260
L-365,260 |
Others | Others |
cholecystokinin receptor 2 (CCK2) antagonist | |||
T15101 |
Devazepide
L-364,718,地伐西匹,MK-329 |
Others | Others |
Devazepide is a competitive and orally active nonpeptide antagonist of cholecystokinin (CCK) receptor (IC50s: 81 pM, 45 pM, and 245 nM for rat pancreatic, bovine gallbladder and guinea pig brain CCK receptors, respectively). | |||
T26198 |
Snf 9007
Snf-9007,Asp-tyr-D-phe-gly-trp-(N-Me)nle-asp-phe-NH2,Snf9007 |
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Snf 9007 is an antagonist of cholecystokinin. | |||
T34668 |
Snf 8814
Snf-8814,Snf8814 |
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Snf 8814 is an analog of centrally selective cholecystokinin. |