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Search Results for " autonomic "

13

抑制剂 & 化合物

1

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T1162	Acipimox Olbemox,K-9321,阿西莫司,阿昔莫司	Others	Others
	Acipimox (K-9321) 是烟酸类似物，能够急性抑制脂解作用，抑制全身游离脂肪水平，改善胰岛素敏感性。
TP1793	Nociceptin (1-13), amide	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	Nociceptin (1-13), amide 是一种 ORL1 (OP4) 受体激动剂，与大鼠前脑膜结合的 Ki 为 0.75 nM，对小鼠输精管的 pEC50 为 7.9。
T24064	Fipamezole JP-1730,BVF-025,JP 1730,JP1730	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Fipamezole 是一种有效的 α2肾上腺素能受体拮抗剂，可能用于研究帕金森病自主神经功能障碍。
T2547	Droxidopa 屈昔多巴,屈西多巴,SM5688,DOPS,L-DOPS	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Droxidopa (L-DOPS) 是 Droxidopa (w/w80%) 和 Pharmaceutical starch (w/w20%) 的混合物，能透过血脑屏障，可作为神经递质去甲肾上腺素和肾上腺素的原药。
T20344	Acetylcholine bromide	Others	Others
	Acetylcholine bromide 是乙酰胆碱的溴化物盐。它是一种神经递质，存在于神经肌肉接头、自主神经节、副交感神经效应器接头、交感神经效应器接头的一个子集以及中枢神经系统的许多部位。
T3289L	Amifostine Hydrate
	Amifostine Hydrate is a radiation protective agent that induces splenic vasodilation and blocks autonomic ganglion.
T33696	NK-1145 NK-1145 hydrocholdoride,NK 1145,NK1145
	Nk-1145 is a parasympathetic drug of the autonomic nervous system, which can cause behavioral stimulation and excitement.
T3289L2	Amifostine sodium WR-2721 sodium,WR2721 sodium,WR 2721 sodium
	Amifostine sodium is a phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
T69023	Hexamethonium chloride
	Hexamethonium chloride is a preferential nicotinic receptor blocker at the level of autonomic ganglia. It has been shown to cross the blood-brain barrier only in high doses.
T78584	Prostaglandin D3 PGD3	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Prostaglandin D3 (PGD3) 是具有抑制人类血小板聚集和调节自主神经传递功能的前列腺素类化合物。
T68811	Trimetaphan camsilate
	Trimetaphan camsilate is a drug that counteracts cholinergic transmission at the ganglion type of nicotinic receptors of the autonomic ganglia and therefore blocks both the sympathetic nervous system and the parasympathetic nervous system. It acts as a non-depolarizing competitive antagonist at the nicotinic acetylcholine receptor, is short-acting, and is given intravenously.
T71236	Oxybutynin R-isomer HCl
	Oxybutynin R-isomer , also known as Aroxybutynin, is a muscarinic receptor antagonist. Aroxybutynin is the optically avtice inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells. Oxybutynin exerts direct antispasmodic effect on smooth muscle and inhibits the muscarinic action of acetylcholine on smooth muscle. It exhibits one-fifth of the anticholinergic activity of atropine on the rabbit detrusor muscle, but four to ten times the antispasmodic activity. No blo...
T76127	Urocortin II, mouse
	Urocortin II, mouse 是一种选择性的 2 型促肾上腺皮质激素释放因子 (CRF2) 受体内源性多肽激动剂，对CRFR2和CRFR1的Ki 值分别为 0.66 nM 和 ﹥100 nM。Urocortin II, mouse 通过以 cAMP/PKA 和 Ca2+/CaMKII 依赖性方式激活 CRF2 受体。Urocortin II, mouse 在中枢神经系统的离散区域表达，并激活参与内脏感觉信息处理和调节自主神经外流的中枢神经元。

化合物

Cat.No: T1162

Synonym: Olbemox,K-9321,阿西莫司,阿昔莫司

Target: Others

Nociceptin (1-13), amide

Cat.No: TP1793

Target: Opioid Receptor

Cat.No: T24064

Synonym: JP-1730,BVF-025,JP 1730,JP1730

Target: Adrenergic Receptor

Cat.No: T2547

Synonym: 屈昔多巴,屈西多巴,SM5688,DOPS,L-DOPS

Target: Adrenergic Receptor

Acetylcholine bromide

Cat.No: T20344

Target: Others

Amifostine Hydrate

Cat.No: T3289L

Cat.No: T33696

Synonym: NK-1145 hydrocholdoride,NK 1145,NK1145

Amifostine sodium

Cat.No: T3289L2

Synonym: WR-2721 sodium,WR2721 sodium,WR 2721 sodium

Hexamethonium chloride

Cat.No: T69023

Prostaglandin D3

Cat.No: T78584

Synonym: PGD3

Target: Prostaglandin Receptor

Trimetaphan camsilate

Cat.No: T68811

Oxybutynin R-isomer HCl

Cat.No: T71236

Urocortin II, mouse

Cat.No: T76127

Cat. No.	Product Name	Target	Signaling Pathways
T6751	Acetylcholine iodide Acetylcolina	Others	Others
	Acetylcholine iodide (Acetylcolina) 是一种在中枢和外周神经系统中常见的神经递质。

天然产物

Acetylcholine iodide

Cat.No: T6751

Synonym: Acetylcolina

Target: Others

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