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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T0840	Methimazole Tapazole,Thiamazole,甲巯咪唑	Thyroid hormone receptor(THR)	Endocrinology/Hormones
	Methimazole (Thiamazole) 是抗甲状腺化合物，具有显著的肝毒性，常用于研究甲亢。
T0952	Carbimazole 卡比马唑,Athyromazole,卡比吗唑,Carbimazol,Neomercazole	Thyroid hormone receptor(THR)	Endocrinology/Hormones
	Carbimazole (Athyromazole) 是咪唑类甲状腺拮抗试剂，在体内快速转化为 MMI 而发挥作用，在体外可转化为甲咪唑，可用于 Graves 病的研究。
T8612	1-Methyl-2-(Methylthio)iMidazole	Others	Others
	1-Methyl-2-(Methylthio)iMidazole 是 Methimazole 的杂质，Methimazole 是一种硫脲类抗甲状腺药物。
T0304	Methylthiouracil 甲基硫脲嘧啶,甲硫氧嘧啶,NSC-193526,NSC-9378,MTU	ERK; Antiviral; TNF; NF-κB; Interleukin	Apoptosis; Immunology/Inflammation; MAPK; NF-κB
	Methylthiouracil (NSC-193526) 是一种抗甲状腺剂。它抑制TNF-α和IL-6的产生以及NF-κB 和ERK1/2的活化。
T12011	Methimazole D3	Others	Others
	Methimazole D3, a deuterium-labeled version of Methimazole, serves as an antithyroid medication for treating hyperthyroidism in both humans and animals.
T66029	3,4-Dehydro-L-proline
	The leguminous shrub,Leucaena leucocephala(Leucaena) is wide‐spread in tropical and subtropical agricultural systems and provides a ready source of protein for livestock. However, the presence of mimosine, a non‐protein, amino acid comprising about 12% of the dry matter in growing tips ofLeucaena, is toxic to animals. Mimosine is degraded rapidly in the rumen to produce 3,4‐dihydroxypyridine (3,4‐DHP) and 2,3‐dihydroxypyridine (2,3‐DHP), both of which remain toxic to animals[1]. 3,4-DHP, as a de...

化合物

Methimazole

Cat.No: T0840

Synonym: Tapazole,Thiamazole,甲巯咪唑

Target: Thyroid hormone receptor(THR)

Carbimazole

Cat.No: T0952

Synonym: 卡比马唑,Athyromazole,卡比吗唑,Carbimazol,Neomercazole

Target: Thyroid hormone receptor(THR)

1-Methyl-2-(Methylthio)iMidazole

Synonym: 甲基硫脲嘧啶,甲硫氧嘧啶,NSC-193526,NSC-9378,MTU

Target: ERK, Antiviral, TNF, NF-κB, Interleukin

3,4-Dehydro-L-proline

Cat.No: T66029

Synonym:

Target:

Cat. No.	Product Name	Target	Signaling Pathways
TN6798	Progoitrin	Others	Others
	Progoitrin 是一种硫代葡萄糖苷，与受感染作物中占主导地位。它对甲状腺活性具有抑制作用。
T1310	2-Thiouracil Thiouracil,硫代由雪,Deracil,2-硫脲嘧啶	Thyroid hormone receptor(THR); NO Synthase	Endocrinology/Hormones; Immunology/Inflammation
	2-Thiouracil (Deracil) 是神经型一氧化氮合酶 (nNOS) 的选择性抑制剂(Ki:20 μM)，是一种抗甲状腺化合物，可用作高度特异性的黑色素瘤探测物。
T2S1778	DL-Goitrin DL-甲状腺肿素,板蓝根,Goitrin,(R,S)-告依春	Others	Others
	DL-Goitrin 也称为 (R,S)-Goitrin，由 epigoitrin (R-Goitrin) 和告依春 (S-Goitrin) 两种异构体组成，是板蓝根的成分。