搜索结果

Search Results for " antiobesity "

抑制剂 & 化合物

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T8511	TM38837	Cannabinoid Receptor	GPCR/G Protein
	TM38837 是外周选择性大麻素受体1型受体拮抗剂。它减少精神病副作用的倾向。它对大脑的渗透率有限，以降低或防止 CNS 不良反应，并保留潜在的抗肥胖作用。
T16074	Mifobate SR-202,米福贝特	PPAR	DNA Damage/DNA Repair; Metabolism
	Mifobate (SR-202) 是一种有效且特异性的 PPARγ拮抗剂，可选择性抑制噻唑烷二酮 (TZD) 诱导的 PPARγ 转录活性，IC50为140 μM，具有抗肥胖和抗糖尿病作用。
T0533	N-Aminopiperidine hydrochloride Piperidin-1-amine hydrochloride,N-氨基哌啶盐酸盐	Others	Others
	N-Aminopiperidine hydrochloride (Piperidin-1-amine hydrochloride) 是大麻素受体 1 拮抗剂 Rimonabant（一种抗肥胖剂）的代谢物(M1)。
T28565	Ro 22-0654 Ro-22-0654
	Ro 22-0654, a novel lipid synthesis inhibitor, has antiobesity effects.
T27923	LY 79771 Lilly 79771,LY-79771,LY79771
	LY-79771, a phenethanolamine antiobesity agent, can be effective in preventing fat regain following energy deprivation.
T79340	GLS1 Inhibitor-7	Glutaminase	Proteases/Proteasome
	GLS1 Inhibitor-7 (compound 4d) 作为一种GLS1 抑制剂，表现出抑制浓度50%所需浓度（IC50）为46.7 μM，潜在用途涉及抗癌、抗衰老和抗肥胖。
T35597	Neuromedin U-23 (rat) (trifluoroacetate salt)
	Neuromedin U-23 (NMU-23) is a neuropeptide involved in diverse biological processes, including smooth muscle contraction, energy homeostasis, and nociception.1It is an agonist of neuromedin-U receptor 1 (NMUR1; EC50= 0.17 nM for the human receptor in a calcium mobilization assay using HEK293 cells) and NMUR2 (EC50= ~1.4-2 nM for arachidonic acid release in CHO cells expressing the human receptor).2,3NMU-23 (1 μM) induces contractions in isolated rat colon smooth muscle strips.4It decreases body ...

化合物

TM38837

Cat.No: T8511

Synonym:

Target: Cannabinoid Receptor

Mifobate

Cat.No: T16074

Synonym: SR-202,米福贝特

Target: PPAR

N-Aminopiperidine hydrochloride

Cat.No: T0533

Synonym: Piperidin-1-amine hydrochloride,N-氨基哌啶盐酸盐

Target: Others

Ro 22-0654

Cat.No: T28565

Synonym: Ro-22-0654

Target:

LY 79771

Cat.No: T27923

Synonym: Lilly 79771,LY-79771,LY79771

Target: Glutaminase

Neuromedin U-23 (rat) (trifluoroacetate salt)

Cat.No: T35597

Synonym:

Target:

Cat. No.	Product Name	Target	Signaling Pathways
T2840	Phloracetophenone 2,4,6-三羟基苯乙酮,2,4,6-trihydroxyacetophenone,1-(2,4,6-Trihydroxyphenyl)ethanone	Others; P450; Antibacterial; Antibiotic	Metabolism; Microbiology/Virology; Others
	Phloracetophenone (1-(2,4,6-Trihydroxyphenyl)ethanone) 是多叶姜黄中苯乙酮糖苷的糖苷配基部分，具有抗肥胖，降血脂和降低胆固醇作用，能够增强胆固醇 7α-羟化酶的活性。
TN5090	Tachioside	Glucokinase	Metabolism
	Tachioside has antiobesity, antioxidant and α-glucosidase inhibitory activities, it decreases lipid content in 3T3-L1 adipocytes by inhibiting lipogenesis, shows antiobesity activities. Tachioside can inhibit nitric oxide production in lipopolysaccharides-stimulated RAW 264.7 cells with IC50 value of 12.14 μM.
TN3989	Erycibelline	LDL; PPAR	DNA Damage/DNA Repair; Metabolism
	Erycibelline has antiobesity activity, it may be a useful therapeutic agent for body weight control by downregulating adipogenesis and lipogenesis.
TN1615	Epitheaflagallin 3-O-gallate 表没食子儿茶素没食子酸酯	MMP	Proteases/Proteasome
	Epitheaflagallin 3-O-gallate is a promising functional food material with potential antiobesity and antiperiodontal disease activities, it suppresses tumor growth through the suppression of angiogenesis.
T75424	(±)-Evodiamine
	(±)-Evodiamine，一种天然生物碱，作为Top1的抑制剂，展现了抗炎、抗肥胖及抗肿瘤特性。(±)-Evodiamine能够通过诱导细胞凋亡来抑制多种肿瘤细胞的增殖。