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Search Results for " antimutagenic "

5

抑制剂 & 化合物

11

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T24957	(L)-Canavanine AI3 52153,AI352153,AI3-52153
	(L)-Canavanine is antimutagenic activity.
T40663	9,10-Dichlorostearic acid
	9,10-Dichlorostearic acid is a chlorinated stearic acid that possesses antimutagenic properties. In vitro studies show that this compound induces membrane damage in mammalian tumor cells by causing leakage of adenosine triphosphate (ATP).
T40345	AV-153
	AV-153 is a 1,4-dihydropyridine derivative with antimutagenic properties. It intercalates into DNA at single strand breaks, resulting in reduced DNA damage and stimulation of DNA repair in human cells in vitro. AV-153 also interacts with thymine and cytosine and influences poly(ADP)ribosylation. Moreover, AV-153 exhibits anti-cancer activity.
T60649	AV-153 free base
	AV-153 free base 是一种 1,4-二氢吡啶(1,4-DHP) 衍生物。AV-153 free base 是一种抗诱变剂，具有抗癌活性。AV-153 free base 可以与胞嘧啶和胸腺嘧啶相互作用，并影响聚 (ADP) 核糖基化。在体外实验中，AV-153 free base 在 DNA 的单链断裂处插入到 DNA 并减少 DNA 损伤，刺激 DNA 修复。
T35980	Bilirubin Conjugate (sodium salt)
	Bilirubin conjugate is a stable, water-soluble ditaurate derivative of bilirubin meant to mimic endogenous bilirubin glucuronide derivatives. In vivo, bilirubin circulates in the plasma and is taken up by hepatocytes and conjugated to one or two glucuronic acids in a reaction catalyzed by UDP glucuronidase to form bilirubin mono or diglucuronide. This water-soluble form is then excreted from the liver in bile in the feces or is converted to urobilinogen and excreted in the urine. In addition to ...

化合物

Cat.No: T24957

Synonym: AI3 52153,AI352153,AI3-52153

9,10-Dichlorostearic acid

Cat.No: T40663

Cat.No: T40345

AV-153 free base

Cat.No: T60649

Bilirubin Conjugate (sodium salt)

Cat.No: T35980

Cat. No.	Product Name	Target	Signaling Pathways
T2934	Bilirubin 胆红素,Bilibubin,Principal bile pigment,Hematoidin,Hemetoidin	Endogenous Metabolite	Metabolism
	Bilirubin (Principal bile pigment) 是血红素分解代谢产生的黄色产物，是肝功能的重要指标。Bilirubin 具有抗诱变和抗氧化作用。
TN3207	7,3′,4′-Tri-O-methyleriodictyol 7,3',4'-Tri-O-methyleriodictyol	Others	Others
	7, 3',4'-Tri-O-methyleriodictyol has antimutagenic activity.
TN1126	Sakuranetin	VEGFR; NF-κB; PPAR; Antifungal	Angiogenesis; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; NF-κB; Tyrosine Kinase/Adaptors
	Sakuranetin 是一种大米黄酮类植物抗毒素，能改善 LPS 诱导的急性肺损伤，具有抗炎、抗真菌和抗氧化作用。
TN2078	Pinocembrin chalcone 2',4',6'-Trihydroxychalcone,Pinocembrinchalcone	Calcium Channel; Tyrosinase; Antibacterial; Antifection	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Proteases/Proteasome
	Pinocembrin chalcone 是一种具有抗诱变作用的酪氨酸酶抑制剂。 Pinocembrin 查尔酮可用于预防胃溃疡的研究。
T6S0078	Oxypeucedanin hydrate Prangolarin Hydrate,水合氧化前胡素	Antioxidant	oxidation-reduction
	Oxypeucedanin hydrate (Prangolarin Hydrate) 是一种分离自D. anethifolia 中的天然香豆素化合物，存在于几种植物中，具有抗感染和抗真菌活性。
TN2058	Persicogenin	Anti-infection	Microbiology/Virology
	Persicogenin 是分离自 Rhus retinorrhoea 中，具有抗癌作用。
T3S1858	Lutein Vegetable Lutein,叶黄素,Xanthophyll,Bo-Xan,Xantofyl	Antibacterial	Microbiology/Virology
	Lutein (Xantofyl) 具有抗肿瘤作用。它具有抗诱变作用。它具有广泛的抗菌作用。它可能对治疗黄斑变性有用。
TN1711	Gossypetin	Antioxidant; p38 MAPK; MAPK; Antibacterial	MAPK; Microbiology/Virology; oxidation-reduction
	Gossypetin 是一种可从Rhodiola rosea Linn.中提取的六羟基化的类黄酮，是一种有效的 MKK3 和 MKK6 抑制剂，可强烈减弱 MKK3/6-p38 信号传导途径。Gossypetin 具有抗突变、抗动脉粥样硬化、抗氧化以及细胞保护和抗菌作用，它通过下调溶酶体酪蛋白酶 K 的活性和诱导肌动蛋白环破骨细胞中的自噬相关蛋白来抑制骨吸收。
T3794	Pentagalloylglucose Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose,1,2,3,4,6-五没食子酰葡萄糖	Influenza Virus	Microbiology/Virology
	1,2,3,4,6-O-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) 存在于多种植物中，具有重要的药理作用。Pentagalloylglucose 表现出显著的抗狂犬病病毒 (RABV) 活性。
TN5040	Soyasaponin IV	Others	Others
	Soyasaponin IV has hepatoprotective activity.It also has antimutagenic activity in mammalian cells.
T81117	Spilanthol
	Spilanthol为一具有多种生物活性的化合物，包括镇痛、神经保护、抗氧化、抗诱变、抗癌、抗炎、抗菌以及杀虫作用。该化合物能够通过诱导cAMP抑制尿浓缩的负调节机制，且可作为利尿剂研究的候选物。

天然产物

Cat.No: T2934

Synonym: 胆红素,Bilibubin,Principal bile pigment,Hematoidin,Hemetoidin

Target: Endogenous Metabolite

7,3′,4′-Tri-O-methyleriodictyol

Cat.No: TN3207

Synonym: 7,3',4'-Tri-O-methyleriodictyol

Target: Others

Cat.No: TN1126

Target: VEGFR, NF-κB, PPAR, Antifungal

Pinocembrin chalcone

Cat.No: TN2078

Synonym: 2',4',6'-Trihydroxychalcone,Pinocembrinchalcone

Target: Calcium Channel, Tyrosinase, Antibacterial, Antifection

Oxypeucedanin hydrate

Cat.No: T6S0078

Synonym: Prangolarin Hydrate,水合氧化前胡素

Target: Antioxidant

Cat.No: TN2058

Target: Anti-infection

Cat.No: T3S1858

Synonym: Vegetable Lutein,叶黄素,Xanthophyll,Bo-Xan,Xantofyl

Target: Antibacterial

Cat.No: TN1711

Target: Antioxidant, p38 MAPK, MAPK, Antibacterial

Pentagalloylglucose

Cat.No: T3794

Synonym: Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose,1,2,3,4,6-五没食子酰葡萄糖

Target: Influenza Virus

Cat.No: TN5040

Target: Others

Cat.No: T81117

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