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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T26683 AUTEN-67

Autophagy enhancer 67,MTMR14 inhibitor,AUTEN67

AUTEN-67 is a specific inhibitor of MTMR14 and autophagy enhancer with potent antiaging and neuroprotective effects. AUTEN-67 also delays the onset and decreases the severity of Huntington's disease.
T79340 GLS1 Inhibitor-7

Glutaminase Proteases/Proteasome
GLS1 Inhibitor-7 (compound 4d) 作为一种GLS1 抑制剂,表现出抑制浓度50%所需浓度(IC50)为46.7 μM,潜在用途涉及抗癌、抗衰老和抗肥胖。

化合物

AUTEN-67
Cat.No: T26683
Synonym: Autophagy enhancer 67,MTMR14 inhibitor,AUTEN67
Target:
GLS1 Inhibitor-7
Cat.No: T79340
Synonym:
Target: Glutaminase
Cat. No. Product Name Target Signaling Pathways
T4S1820 Parishin

巴利森苷A,派立辛,Parishin A

Others Others
Parishin (Parishin A) A 是一种酚类葡萄糖苷,从天麻中分离得到。Parishin 通过调节 Sir2/Uth1/TOR 信号通路而具有抗衰老作用,并延长酵母寿命。
TN1072 Lappaol A

P-gp; JNK MAPK; Membrane transporter/Ion channel; Neuroscience
Lappaol A has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol A also has potential chemosensitizing activity, it may be candidates for developing novel adjuvant an
TN1821 Kaempferol 3-O-arabinoside

山奈酚-3-O-α-L-吡喃阿拉伯糖苷,堪非醇 3-O-阿拉伯糖苷

ROS; Antifection Immunology/Inflammation; Microbiology/Virology
Kaempferol-3-O-α±-D-arabinoside displays cytotoxic and high antioxidant activity.Kaempferol-3-O-arabinoside and kaempferol-3-O-glucoside can function as antioxidants in biological systems, particularly skin exposed to UV radiation by scavenging ROS, and protect cellular membrane against ROS; they can be applicable to new cosmeceuticals for antioxidant, antiaging, and antibacterial activity.
TN4410 Lappaol C

P-gp; JNK MAPK; Membrane transporter/Ion channel; Neuroscience
Lappaol C has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol C also has potential chemosensitizing activity, it may be candidates for developing novel adjuvant an
TN4411 Lappaol F

CDK; P-gp; JNK Cell Cycle/Checkpoint; MAPK; Membrane transporter/Ion channel; Neuroscience
1. Lappaol F has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. <br/> 2. Lappaol F has potential chemosensitizing activity, it may be candidates for developing novel adju

天然产物

Parishin
Cat.No: T4S1820
Synonym: 巴利森苷A,派立辛,Parishin A
Target: Others
Lappaol A
Cat.No: TN1072
Synonym:
Target: P-gp, JNK
Kaempferol 3-O-arabinoside
Cat.No: TN1821
Synonym: 山奈酚-3-O-α-L-吡喃阿拉伯糖苷,堪非醇 3-O-阿拉伯糖苷
Target: ROS, Antifection
Lappaol C
Cat.No: TN4410
Synonym:
Target: P-gp, JNK
Lappaol F
Cat.No: TN4411
Synonym:
Target: CDK, P-gp, JNK
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