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Cat. No. Product Name Target Signaling Pathways
T2316 Omarigliptin

MK-3102,奥格列汀

Proteasome; DPP-4 Proteases/Proteasome; Ubiquitination
Omarigliptin (MK-3102) 是高效选择性 DPP4抑制剂,IC50=为1.6nM。
T6766 Atipamezole

Antisedan,阿替美唑,MPV 1248

Adrenergic Receptor GPCR/G Protein; Neuroscience
Atipamezole (Antisedan) 是 α2-肾上腺素受体拮抗剂,Ki=1.6 nM。
T6765 Atipamezole hydrochloride

阿替美唑盐酸盐,MPV-1248 hydrochloride,Antisedan

Adrenergic Receptor GPCR/G Protein; Neuroscience
Atipamezole hydrochloride (MPV-1248 hydrochloride) 是一种 α2-肾上腺素受体拮抗剂,Ki=1.6 nM。
T21446 Rotigotine Hydrochloride

Rotigotine (Hydrochloride),N 0923,N-0924,Rotigotine HCl,盐酸罗替戈汀,N-0923,罗替戈汀盐酸盐

Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor GPCR/G Protein; Neuroscience
Rotigotine Hydrochloride (N-0924) 是多巴胺受体激动剂,是5-HT1A 受体的部分激动剂,以及α2B-肾上腺素受体的拮抗剂,具有抗帕金森病活性。
T1406L Amantadine sulfate

1-Adamantanamine Sulfate

Amantadine is used both as an antiviral and an anti-parkinsonian drug. Amantadine is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake. The drug has many effects in the brain, including the rel
T74770 D-685

D-685作为D-520的前体药物,在帕金森病(PD)血脂化动物模型中展示了优于D-520的体内抗PD功效。此外,D-685能降低人类α-突触核蛋白(α-syn)的累积,且具有更高的大脑透过性。

化合物

Omarigliptin
Cat.No: T2316
Synonym: MK-3102,奥格列汀
Target: Proteasome, DPP-4
Atipamezole
Cat.No: T6766
Synonym: Antisedan,阿替美唑,MPV 1248
Target: Adrenergic Receptor
Atipamezole hydrochloride
Cat.No: T6765
Synonym: 阿替美唑盐酸盐,MPV-1248 hydrochloride,Antisedan
Target: Adrenergic Receptor
Rotigotine Hydrochloride
Cat.No: T21446
Synonym: Rotigotine (Hydrochloride),N 0923,N-0924,Rotigotine HCl,盐酸罗替戈汀,N-0923,罗替戈汀盐酸盐
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
Amantadine sulfate
Cat.No: T1406L
Synonym: 1-Adamantanamine Sulfate
Target:
D-685
Cat.No: T74770
Synonym:
Target:
TargetMol Loading
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