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3

抑制剂 & 化合物

7

天然产物

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Cat. No. Product Name Target Signaling Pathways
T38272 Thiacloprid

AChR; Parasite Microbiology/Virology; Neuroscience
Thiacloprid 属于氯烟碱类杀虫剂,主要用于防治蔬菜和果园中的蚜虫。它会破坏 DNA 的稳定性,通过疏水或氢相互作用,结合到小沟槽中,改变 DNA 的结构和稳定性。
T40833 ω-Hydroxy-DEET

ω-Hydroxy-DEET, a significant metabolite of the insect repellent N-N-diethyl-meta-toluamide (DEET), exhibits anti-proliferative properties. DEET, renowned for being a spatial repellent and irritant, is frequently employed to deter mosquito contact.
T35776 Janthitrem A

Janthitrem A is a mycotoxin that has been found inP. janthinellum.1It induces tremors in mice and decreases the time to fall from the rotarod when administered at a dose of 4 mg/kg.2Janthitrem A (20 μg/g) also reducesW. cervinatalarvae weight gain and food consumption. 1.Gallagher, R.T., Latch, G.C., and Keogh, R.G.The janthitrems: Fluorescent tremorgenic toxins produced by Penicillium janthinellum isolates from ryegrass pasturesAppl. Environ. Microbiol.39(1)272-273(1980) 2.Babu, J.V., Popay, A....

化合物

Thiacloprid
Cat.No: T38272
Synonym:
Target: AChR, Parasite
ω-Hydroxy-DEET
Cat.No: T40833
Synonym:
Target:
Janthitrem A
Cat.No: T35776
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T11680 Isoasatone A

P450 Metabolism
Isoasatone A 是一种具有抗虫作用的天然产物,分离自Heterotropa takaoiM。它作用于细胞色素 P450 单加氧酶和谷胱甘肽转移酶,产生抗S. litura 作用。
T9279 nerolidol acetate

Others Others
Nerolidol acetate是一种具有抗癌、抗炎、抗菌和抗虫的活性的天然倍半萜。Nerolidol acetate可抑制寄生虫活动,抑制吸血虫病、线虫病以及疟疾等。Nerolidol acetate可保护细胞免受脂质、蛋白质和 DNA 的氧化损伤,对小鼠海马神经细胞具有保护作用。
TN1401 Arjunetin

Others Others
Arjunetin, an insect feeding-deterrent and growth inhibitor, shows antioxidant and anti-inflammatory activities.
TN4403 Lactupicrin

Antifection Microbiology/Virology
Lactupicrin has antimicrobial and anti-cancer effects, it also protect the plant from insect feeding.
TN4795 Piperenone

PAFR GPCR/G Protein
Piperenone is an insect antifeeding substance. It has anti-platelet-activating factor(PAF) activities, is a PAF-acether antagonist.
TN4659 Nimbin

COX Immunology/Inflammation; Neuroscience
Nimbin is an anti-pyretic, can be used to treat arthritis, hypoglycaemia, peptic ulcers, anti-secretory activity, and it can also be used as an antibiotic. Nimbin requires to elicit a 50% inhibition of this steroid hydroxylase activity in the three insect
TN5228 Vestitol

Antifection Microbiology/Virology
Vestitol is a phytoalexin with insect feeding-deterrent activity, it has antioxidant, anti-inflammatory and antimicrobial activities, it can inhibit neutrophil migration at a dose of 10 mg/kg, and shows MICs ranging from 25-50 to 50-100 ug/mL and MBCs ranging from 25-50 to 50-100 ug/mL.Vestitol exerts a limited inhibitory effect on S. hermonthica germination, it can significantly inhibit seedling growth, it also contributes, at least in part, to the host's defence mechanism and acts as a chemica...

天然产物

Isoasatone A
Cat.No: T11680
Synonym:
Target: P450
nerolidol acetate
Cat.No: T9279
Synonym:
Target: Others
Arjunetin
Cat.No: TN1401
Synonym:
Target: Others
Lactupicrin
Cat.No: TN4403
Synonym:
Target: Antifection
Piperenone
Cat.No: TN4795
Synonym:
Target: PAFR
Nimbin
Cat.No: TN4659
Synonym:
Target: COX
Vestitol
Cat.No: TN5228
Synonym:
Target: Antifection
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