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29

抑制剂 & 化合物

9

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T61317	Anabolic agent-1
	Anabolic agent-1 is a novel bone morphogenetic protein-2 up regulator, with the capability of rectifying bone loss in patients and exhibiting versatile clinical applicability.
T39508	KY-02327	Others	Others
	KY-02327 是 KY-02061的一种类似物，具有代谢稳定性。KY-02327是Dishevelled (Dvl)-CXXC5相互作用抑制剂。KY-02327激活Wnt/β-catenin 途径，从而促进成骨细胞分化。
T26539	AC-262536 AC262536,4-(3-内型-羟基-8-氮杂双环[3.2.1]辛烷-8-基)萘-1-甲腈	Androgen Receptor	Endocrinology/Hormones
	AC-262536 是非甾体雄激素受体选择性调节剂，具有有益的合成代谢作用。它可以强效激动雄激素受体，亲和力为1-10 nM。
T19213	Boldenone Cypionate	Others; Androgen Receptor	Endocrinology/Hormones; Others
	Boldenone Cypionate 是一种雄激素合成代谢类固醇，常被休闲健美运动员和普通健身房成员使用。
T2556	Nandrolone decanoate 癸酸诺龙,19-Nortestosterone decanoate	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	Nandrolone decanoate (19-Nortestosterone decanoate) 是一种合成代谢雄激素，通过涉及谷氨酸诱导的 N-甲基-D-天冬氨酸受体过度兴奋的机制诱导攻击性行为表征。
T11410L	GLPG0492	Androgen Receptor	Endocrinology/Hormones
	GLPG0492 是一种非甾体选择性雄激素受体 (androgen receptor) 调节剂。GLPG0492 在肌肉骨骼疾病如肌萎缩和恶病质的研究方面具有潜在的潜力。
T2408	Ostarine MK-2866,GTX-024,Enobosarm	Androgen Receptor	Endocrinology/Hormones
	Ostarine (MK-2866) 是一种具有合成代谢活性的非甾体药物。选择性雄激素受体调节剂 (SARM) GTx-024 旨在像睾酮一样发挥作用，从而促进和/或维持性欲、生育能力、前列腺生长以及肌肉生长和力量。模仿睾酮的作用，这种药物可以增加瘦体重，从而改善癌症恶病质高代谢状态下的肌肉萎缩。
T21460	Teriparatide acetate hPTH 1-34 (acetate salt),Parathar acetate,Forteo,醋酸立特帕肽	Others	Others
	Teriparatide acetate (Forteo) 是一种 PHT 激动剂，在 HEK293 细胞中的 IC50 为 2 nM。Teriparatide acetate 是一种重组形式的甲状旁腺激素。它是一种有效的合成代谢（即骨骼生长）剂，用于治疗某些形式的骨质疏松症。间歇使用特立帕肽比破骨细胞更能激活成骨细胞，从而导致骨骼整体增加。
T31654	Epimetendiol 17-Epimetendiol,J393.531K,17Epimetendiol,17 Epimetendiol
	Epimetendiol is an anabolic agent
T19195	Androstenediol 17-acetate	Others	Others
	Androstenediol 17-acetate is a synthetic anabolic-androgenic steroid and an androgen ester.
T13921	Testosterone tridecanoate	Others	Others
	Testosterone tridecanoate is a prodrug of testosterone. Testosterone is an anabolic steroid and primary male sex hormone.
T19563	Stanolone benzoate DHTB,Androstanolone benzoate,Dihydrotestosterone benzoate	Others	Others
	Stanolone benzoate is a anabolic steroid and synthetic androgen.
T24168	Insulin B (20-30) Insulin (B20-B30)
	Insulin B (20-30) is a peptide hormone produced by beta cells of the pancreatic islets, and it is considered to be the main anabolic hormone of the body. It is therefore an anabolic hormone, promoting the conversion of small molecules in the blood into la
T40809	2α-Methyl androsterone
	2α-Methyl androsterone is an anabolic androgenic steroid metabolite of mesterolone and drostanolone.
T33725	Norgestrienone Planor,A-301,A301,Ogyline,A 301
	Nogotrienone is an anabolic steroid with fertility and contraceptive activity that has been studied as a therapeutic agent for hereditary angioneurotic edema.
T30558	Bolandiol dipropionate
	Bolandiol dipropionate is an Anabolic.
T30560	Bolmantalate Bolmantalatum,Lilly 38851,LY38851,LY-38851,LY 38851
	Bolmantalateis an androgen and anabolic steroid.
T34813	Testosterone ketolaurate Testosterone 3-oxododecanoate,Testosteroni ketolauras,十二酮酸睾酮
	Testosterone ketolaurate is an androgen and anabolic steroid and a testosterone ester.
T24169	Insulin B (22-30) Insulin (B22-B30)
	Insulin B (22-30) is a peptide hormone produced by beta cells of the pancreatic islets, and it is considered to be the main anabolic hormone of the body. It is therefore an anabolic hormone, promoting the conversion of small molecules in the blood into la
T37603	Osteogenic Growth Peptide (10-14)
	YGFGG, C-terminal pentapeptide fragment of the osteogenic growth peptide (OGP), (H-8640), showed the full spectrum of OGP-like bioactivities. It has attracted considerable interest as bone anabolic agent and hematopoietic stimulator.
T61590	DS96432529
	DS96432529 是一种具有口服活性和CDK8抑制活性的强效骨合成代谢剂。
T31200	Dansylmethionine Dansyl methionine,Dansyl-met
	Dansylmethionine is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. Although these anabolic reactions occur throughout the body, most SAM-e is produced and consumed in the liver. More than 40 methyl transfe
T82534	Domagrozumab PF-06252616
	Domagrozumab是针对人肌生成抑制素的人源化单克隆抗体，其KD值为2.6 pM。该抗体能促进肌肉合成代谢，应用于杜氏肌营养不良症(DMD)研究领域。
TP1124	IGF-I (24-41) Insulin-like Growth Factor I (24-41),IGF-I 24-41
	IGF-I (24-41) is a 24-41 amino acid fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective
TP1123	IGF-I (24-41) TFA (135861-49-3 free base) Insulin-like Growth Factor I (24-41) (TFA),IGF-I (24-41) TFA
	IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions).IGF-I (24-41) (TFA) is amino acids 24 to 41 fragment of Insulin-like Growth
T73731	10-Formyltetrahydrofolic acid disodium
	10-Formyltetrahydrofolic acid disodium 为四氢叶酸衍生物，作为甲酰基供体参与合成代谢。该化合物作为甲酰基转移酶反应底物，涉及嘌呤生物合成过程。
T76012	IGF-I (30-41) (TFA)
	IGF-I (30-41) (TFA) 是类胰岛素生长因子I 30 至 41 的氨基酸片段。IGF-I 对生长激素的活性有着重要的作用，但是IGF-I 本身也具有一些自身的特性，如合成代谢、抗氧化、抗炎和细胞保护作用。
T76124	Acyl coenzyme A synthetase
	Acyl coenzyme A synthetase (ACS)，一种生化研究中常用的酶，主要通过两步硫酯化反应激活脂肪酸与辅酶A结合，形成酰基辅酶A。该过程为脂质代谢中的多种合成与分解代谢途径，以及参与TCA循环中的有氧呼吸提供了关键中间物。
T76014	IGF-I (24-41) (TFA)
	IGF-I (24-41) TFA（Insulin-like Growth Factor I (24-41) TFA）是类胰岛素生长因子I的一个氨基酸片段，覆盖24至41位点。作为一种70个氨基酸组成的多肽激素，IGF-I TFA对神经元和神经胶质细胞具有营养作用，而且在调节全身生长激素（GH）活性中扮演关键角色。它还具备合成代谢、抗氧化、抗炎及细胞保护功能，对躯体生长及行为发育调节作用显著。

化合物

Anabolic agent-1

Cat.No: T61317

Cat.No: T39508

Target: Others

Cat.No: T26539

Synonym: AC262536,4-(3-内型-羟基-8-氮杂双环[3.2.1]辛烷-8-基)萘-1-甲腈

Target: Androgen Receptor

Boldenone Cypionate

Cat.No: T19213

Target: Others, Androgen Receptor

Nandrolone decanoate

Cat.No: T2556

Synonym: 癸酸诺龙,19-Nortestosterone decanoate

Target: Others, HIV Protease

Cat.No: T11410L

Target: Androgen Receptor

Cat.No: T2408

Synonym: MK-2866,GTX-024,Enobosarm

Target: Androgen Receptor

Teriparatide acetate

Cat.No: T21460

Synonym: hPTH 1-34 (acetate salt),Parathar acetate,Forteo,醋酸立特帕肽

Target: Others

Cat.No: T31654

Synonym: 17-Epimetendiol,J393.531K,17Epimetendiol,17 Epimetendiol

Androstenediol 17-acetate

Cat.No: T19195

Target: Others

Testosterone tridecanoate

Cat.No: T13921

Target: Others

Stanolone benzoate

Cat.No: T19563

Synonym: DHTB,Androstanolone benzoate,Dihydrotestosterone benzoate

Target: Others

Insulin B (20-30)

Cat.No: T24168

Synonym: Insulin (B20-B30)

2α-Methyl androsterone

Cat.No: T40809

Cat.No: T33725

Synonym: Planor,A-301,A301,Ogyline,A 301

Bolandiol dipropionate

Cat.No: T30558

Cat.No: T30560

Synonym: Bolmantalatum,Lilly 38851,LY38851,LY-38851,LY 38851

Testosterone ketolaurate

Cat.No: T34813

Synonym: Testosterone 3-oxododecanoate,Testosteroni ketolauras,十二酮酸睾酮

Insulin B (22-30)

Cat.No: T24169

Synonym: Insulin (B22-B30)

Osteogenic Growth Peptide (10-14)

Cat.No: T37603

Cat.No: T61590

Dansylmethionine

Cat.No: T31200

Synonym: Dansyl methionine,Dansyl-met

Cat.No: T82534

Synonym: PF-06252616

Cat.No: TP1124

Synonym: Insulin-like Growth Factor I (24-41),IGF-I 24-41

IGF-I (24-41) TFA (135861-49-3 free base)

Cat.No: TP1123

Synonym: Insulin-like Growth Factor I (24-41) (TFA),IGF-I (24-41) TFA

10-Formyltetrahydrofolic acid disodium

Cat.No: T73731

IGF-I (30-41) (TFA)

Cat.No: T76012

Acyl coenzyme A synthetase

Cat.No: T76124

IGF-I (24-41) (TFA)

Cat.No: T76014

Cat. No.	Product Name	Target	Signaling Pathways
T8709	Nandrolone phenylpropionate Nandrolone phenpropionate,苯丙酸诺龙	Androgen Receptor	Endocrinology/Hormones
	Nandrolone phenylpropionate (Nandrolone phenpropionate) 是一种合成代谢类固醇，是一种 19-nortestosterone 的衍生物。它能够促进蛋白质合成，用于缓解组织分解代谢，可以用于骨质疏松症和特纳综合征的研究。
T8117	Metenolone acetate Methenolone acetate,美替诺龙醋酸酯	Others; Androgen Receptor	Endocrinology/Hormones; Others
	Metenolone acetate (Methenolone acetate) 是一种合成代谢类固醇(AAS) 药物，是一种雄激素，主要用于治疗由于骨髓衰竭引起的贫血。
T9171	Methenolone enanthate	Others	Others
	Methenolone enanthate 是一种雄激素和合成代谢类固醇 (AAS) 药物，主要用于治疗由于骨髓衰竭引起的贫血。
T19470	Nandrolone propionate	Others; Androgen Receptor	Endocrinology/Hormones; Others
	Nandrolone propionate 是合成代谢类固醇，主要由雄激素和保氮剂组成，具有作用时间相对较长的特点。
TC0026	Testosterone benzoate	Others	Others
	Testosterone benzoate 是一种合成的注射合成代谢雄激素类固醇 (AAS) 和一种雄激素酯。
T6S0139	Neobavaisoflavone	Apoptosis; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Neobavaisoflavone 是一种从Psoralea corylifolia 的种子中分离出来的类黄酮。它具有抗炎，抗癌和抗氧化的作用。它在中至高浓度下可抑制 DNA 聚合酶，也可抑制血小板聚集。
T20976	Clostebol acetate Clostebolacetate,Clostene,Alfa-Trofodermin,4-CLTA
	Clostebol acetate is a synthetic anabolic-androgenic steroid (AAS) and a derivative of testosterone. It acts as a prodrug of clostebol in the body.
T64533	Ceramide (Egg, Chicken)	Apoptosis	Apoptosis
	Ceramide (Egg, Chicken)在鞘脂的合成代谢和分解代谢途径中起主要作用。Ceramide (Egg, Chicken)刺激许多细胞分化，生长抑制，细胞衰老和凋亡。
TN1778	Isoformononetin 异刺芒柄花素,黄豆苷元杂质	IL Receptor; Antifection	Immunology/Inflammation; Microbiology/Virology
	Isoformononetin shows fungitoxic activity against Cladosporium sphaerospermum; it also has immunomodulatory activity, it inhibits the differentiation of Th17 cells and B-cell lymphopoesis to promote osteogenesis in estrogen-deficient bone loss conditions.

天然产物

Nandrolone phenylpropionate

Cat.No: T8709

Synonym: Nandrolone phenpropionate,苯丙酸诺龙

Target: Androgen Receptor

Metenolone acetate

Cat.No: T8117

Synonym: Methenolone acetate,美替诺龙醋酸酯

Target: Others, Androgen Receptor

Methenolone enanthate

Cat.No: T9171

Target: Others

Nandrolone propionate

Cat.No: T19470

Target: Others, Androgen Receptor

Testosterone benzoate

Cat.No: TC0026

Target: Others

Neobavaisoflavone

Cat.No: T6S0139

Target: Apoptosis, DNA/RNA Synthesis

Clostebol acetate

Cat.No: T20976

Synonym: Clostebolacetate,Clostene,Alfa-Trofodermin,4-CLTA

Ceramide (Egg, Chicken)

Cat.No: T64533

Target: Apoptosis

Isoformononetin

Cat.No: TN1778

Synonym: 异刺芒柄花素,黄豆苷元杂质

Target: IL Receptor, Antifection

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