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80

抑制剂 & 化合物

2

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T6829	EPI-001 EPI001,EPI 001	Apoptosis; Androgen Receptor; PPAR	Apoptosis; DNA Damage/DNA Repair; Endocrinology/Hormones; Metabolism
	EPI-001 是一种选择性雄激素受体 (AR) 的抑制剂，靶向 AR 的反式激活单元 5，可抑制 AR 氨基末端结构域的反式激活，IC50值约为 6 μM。它也是一种选择性的PPARγ调节剂，对去势抵抗性前列腺癌具有活性。
TP1031	Tetracosactide Tetracosactrin,替可克肽	Others	Others
	Tetracosactide (Tetracosactrin) 是一种肾上腺皮质激素 (ACTH) 的类似物，能够刺激肾上腺皮质激素分泌。
T5885	N-Acetyl-D-galactosamine GalNAc,2-乙酰胺基-2-脱氧-D-半乳糖	Others	Others
	N-Acetyl-D-galactosamine (GalNAc) 是一种源自半乳糖的末端必需氨基糖，在人体中形成 A 型血的抗原。
T40026	Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- 4-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]butanoic acid	Others	Others
	Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- (4-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]butanoic acid)可用于后续化学的带有烷基接头和末端酸的 Cereblon 配体。
TP1153L	Fibronectin Adhesion-promoting Peptide acetate Fibronectin Adhesion-promoting Peptide acetate(125720-21-0 free base),Heparin Binding Peptide acetate	Others	Others
	Fibronectin Adhesion-promoting Peptide acetate (Heparin Binding Peptide acetate)(125720-21-0 free base) 是在纤连蛋白的羧基末端肝素结合结构域中发现的肝素结合氨基酸序列之一。
TP1315	c-Myc Peptide Trifluoroacetate	Others	Others
	c-Myc Peptide Trifluoroacetate (145646-22-6 free base) 是一种合成肽，对应于人类 c-myc 蛋白的 C 末端氨基酸 (410-419)，参与调控生长相关基因的转录。
TP1615L	IKKγ NBD Inhibitory Peptide acetate IKKγ NBD Inhibitory Peptide acetate(372146-18-4 free base)	NF-κB	NF-κB
	IKKγ NBD Inhibitory Peptide acetate 是一种 NEMO 结合结构域肽（NBD 肽）乙酸盐，对应于 NEMO 氨基末端 α-螺旋区域。它显示可阻断 TNF-α 诱导的 NF-kB 活化。
TP1197	Sincalide SQ19844,辛卡利特,CCK-8,Cholecystokinin octapeptide	Others	Others
	Sincalide (CCK-8) 是一种速效的胆囊收缩素的氨基酸多肽激素类似物，可在胆囊造影术中静脉使用。它的肝胆生理作用是增加胆汁的分泌，使胆囊收缩并使 Oddi 的括约肌松弛，从而使胆汁排入十二指肠。它是一种通过注射促进胆囊收缩并帮助诊断胆囊和胰腺疾病的药物。
TP1280	Hexa-His	Others	Others
	Hexa-His 是融合蛋白的金属结合位点，是一种由 6 个组氨酸构成的六肽。
T9417L	gamma-preprotachykinin amide (72-92) acetate gamma-preprotachykinin amide (72-92) acetate (114882-65-4 Free base)	Others	Others
	gamma-preprotachykinin amide (72-92) acetate 是一种 21 个氨基酸的肽，属于速激肽 (TK) 家族，在其 C 末端序列中包括神经激肽 A (NKA)。它对中枢 NK-2 受体的亲和力高于 NKA；它对 NK-1 受体的亲和力较低，但是，它有效地刺激唾液分泌，这是由 NK-1 受体激活介导的。
TP1604L	Thioredoxin reductase peptide acetate Thioredoxin reductase peptide acetate(950890-23-0 free base)	Others	Others
	Thioredoxin reductase peptide acetate(950890-23-0 free base) 对应于硫氧还蛋白还原酶 (TrxR) 中的 53–67 位残基，用于硫氧还蛋白还原酶研究。哺乳动物硫氧还蛋白还原酶 (TR) 催化硫氧还蛋白 (Trx) 的氧化还原活性二硫键的还原，并且在结构和谷胱甘肽还原酶的作用机制，除了 C 末端的 16 个氨基酸延伸部分含有一个罕见的连位硒硫键。
T32126	Hypusine
	Hypusine is an N-terminal amino alcohol derivative of Lys occurring in bovine brain &
T25371	Emd 55450 Emd55450,Emd-55450
	Emd 55450 is a synthetic renin antagonist. It is an analog of EMD 55068 with terminal amino group blocked by benzyloxycarbonyl group.
TP1136	Secretin (28-54), human Human secretin
	Secretin (28-54), human, is a 27-amino acid residue peptide with a C-terminal amidation, acting on human secretin receptors.
T16173	N-(Amino-PEG5)-N-bis(PEG4-acid)	Others	Others
	N-(Amino-PEG5)-N-bis(PEG4-acid) is a PEG-based PROTAC linker employed for synthesizing PROTACs. It comprises an amino group with two terminal carboxylic acids[1].
T37128	Chemerin-9, Mouse
	Chemokine-like receptor 1 (CMKLR1) agonist (EC50 = 42 nM). Corresponds to C-terminal of full length mouse Chemerin, amino acids 148 - 156.
T71920	9-(Boc-amino)nonanoic Acid
	9-(Boc-amino)nonanoic Acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
T76102	Carboxypeptidase B
	Carboxypeptidase B 是一种肽链外切酶，可专一性地降解肽链。Carboxypeptidase B 从 C 端逐个降解，释放出游离氨基酸。Carboxypeptidase B 只水解以碱性氨基酸（如精氨酸和赖氨酸）为 C 末端残基的肽键。
T70057	14-(Fmoc-amino)-tetradecanoic acid
	14-(Fmoc-amino)-tetradecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. 14-(Fmoc-amino)-tetradecanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
TP1547	Caerulein, desulfated
	Caerulein, desulfated is the desulfurated form of Caerulein. Caerulein is a deceptide with the same five carboxy-terminal amino acids as gastrin and cholecystatin (CCK).
TP1827	Neuronostatin-13 (human) Neuronostatin-13 human
	Neuronostatin-13 (Human) is a 13 amino acid residue peptide with carboxyl-terminal amidation, the primary structure is conserved in human chimpanzee and some other mammals.
TP1153	Fibronectin Adhesion-promoting Peptide Heparin Binding Peptide
	Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide) is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin.
TP1448	Astressin
	Astressin is an amino-terminal truncated analog of CRF that retains high affinity binding to the extracellular domain of the receptor and is believed to act as a neutral competitive antagonist of receptor activation.
T71906	Boc-12-Ado-OH
	Boc-12-Ado-OH can be used as a PROTAC linker in the synthesis of PROTACs. Boc-12-Ado-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
TP1645	β-Amyloid (1-9) β-Amyloid 1-9
	This is an N-terminal fragment of beta amyloid. It consists of amino acid residues 1 to 9. Truncated beta amyloid peptide (10-40) still forms amyloid fibrils and shows fibril polymorphism.
T71872	Boc-8-aoc-oh
	Boc-8-aoc-oh can be used as a PROTAC linker in the synthesis of PROTACs. Boc-8-aoc-oh is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
T70303	N-Boc-15-aminopentadecanoic acid
	N-Boc-15-aminopentadecanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
T71789	Boc-7-Aminoheptanoic acid
	Boc-7-Aminoheptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applicaitons. Boc-7-Aminoheptanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
T71970	Fmoc-7-amino-heptanoic acid
	Fmoc-7-amino-heptanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
T76459	[Tyr12] Somatostatin 28 (1-14)
	[Tyr12] Somatostatin 28 (1-14)，是Somatostatin-28 (1-14)的类似物，属于神经肽生长抑素-28的N-末端片段。
T71919	Boc-10-Aminodecanoic acid
	Boc-10-Aminodecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Boc-10-Aminodecanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
TP1152	Fibronectin Adhesion-promoting Peptide TFA Heparin Binding Peptide TFA
	Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide) is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin. It promotes assembly of mesenchymal stem cell (MSC) spheroids into lar
T83115	Angiogenin Fragment (108-123)
	Angiogenin Fragment (108-123) 为血管生成素C末端的第108至123氨基酸片段，具有抑制其酶促活性和生物活性的功能。
TP1576	SNAP-25 187-203
	This amino acids187 to 203 fragment is derived from the C-terminal helix of synaptosomal-associated protein of 25 kDa (SNAP-25). This peptide is able to rescue exocytosis from botulinum neurotoxin E (BoNT/E)-treated cells, albeit at higher concentrations
TP1032	Transdermal Peptide TFA (918629-48-8 free base) Transdermal Peptide TFA,TD 1 (peptide) (TFA)
	Transdermal Peptide TFA (TD 1 Peptide TFA) is an 11-amino acid polypeptide that binds to Na+/K+ -atpase beta-subunit (ATP1B1) and interacts with the C terminal of ATP1B1.Transdermal Peptide TFA can enhance the transmission of some large molecules in the s
TP2177	Amyloid Precursor C-Terminal Peptide	Others	Others
	Amyloid precursor c-terminal peptide has the amino acid sequence Gly-Tyr-Glu-Asn-Pro-Thr-Tyr-Lys-Phe-Phe-Glu-Gln-Met-Gln-Asn. APP is best known as the precursor molecule whose proteolysis generates beta-amyloid (Aβ), a 37 to 49 amino acid peptide whose am
TP1615	IKKγ NBD Inhibitory Peptide
	A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO with the IKK complex is vital for t
TP1514	α-Neoendorphin (1-8) α-Neoendorphin 1-8
	α-Neoendorphin (1-8) is a 8-amino acid peptide derived from the N-terminal of α-Neoendorphin. α-Neoendorphin is an endogenous opioid peptide and is a part for the neoendorphins which are a group of endogenous opioid peptides derived from the proteolytic c
T76202	Recombinant Proteinase K
	Recombinant Proteinase K为一种serine protease，专门裂解脂肪族及芳香族氨基酸的羧基端肽键，适用于蛋白质消化与清除核酸制剂中的污染。
T81585	Oxyntomodulin (human, mouse, rat) Proglucagon (33-69)
	Oxyntomodulin (human, mouse, rat) (Proglucagon (33-69)) 是由胰高血糖素前体产生，融合了完整胰高血糖素序列和C端八肽，含37个氨基酸。
T76308	Gastric Inhibitory Polypeptide (1-30), porcine
	Gastric Inhibitory Polypeptide (1-30), porcine 缺乏天然胃抑制多肽 (GIP) C 端 12 个氨基酸残基，能够增强胰岛素和生长抑素的释放而发挥生物活性。
T36876	SBP1
	Human ACE2 receptor-derived 23-amino acid peptide. Binds receptor binding domain (RBD) of insect-derived SARS-CoV-2 spike protein (KD = 1.3 μM for N-terminal biotinylated, insect-derived spike protein RBD; see Zhang et al preprint publication). Please note - unpublished, in-house data suggests approximately 75-fold lower affinity for insect-derived SARS-CoV-2 RBD than reported by Zhang et al.
TP1130	β-CGRP, human CGRP-II (Human),Human β-CGRP
	β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascular and nervous systems. β-CGRP contains a disulphide bridge at the N-terminus, a C-terminal phenylal
TP1944	pep2-SVKI
	Inhibitor peptide corresponding to last 10 amino acids of the C-terminus of the GluA2 AMPA receptor subunit. Disrupts binding of GluA2 (at the C-terminal PDZ site) with glutamate receptor interacting protein (GRIP), AMPA receptor binding protein (ABP) and
T35827	Epsilon-V1-2 PKCε Inhibitor Peptide,Protein Kinase Cɛ Inhibitor Peptide,ɛV1-2
	Protein kinase C (PKC ) is a calcium-independent, phospholipid- and diacylglycerol-dependent serine/threonine kinase involved in diverse signaling pathways, including those involved in neuronal signaling, cytoskeletal function, and inflammation.[1] PKC inhibitor peptide is a synthetic peptide corresponding to an amino acid sequence found in the amino terminal C2 domain of most mammalian forms of PKC .[2] It selectively and reversibly inhibits the translocation of PKC to intracellular membrane...
T83221	a-Bag Cell Peptide (1-7)
	α-Bag Cell Peptide (1-7)是α-bag cell peptide的NH2末端片段，具有抑制左上象限(LUQ)神经元及阻止袋细胞去极化的功能。
T80228	r8-Gly-Noxa A BH3
	r8-Gly-Noxa A BH3 是一种源自 Noxa A BH3 (死亡结构域) 结构域氨基酸残基 17 至 36 的具有生物活性的细胞渗透性肽。该肽在氨基末端通过添加 8 个 D-精氨酸残基和一个甘氨酸接头残基而进行了修饰。
T77087	Mipeginterferon alfa-2b
	Mipeginterferon alfa-2b 是一种干扰素IFNA2b 类似物。包括一个 N 末端和 10 个赖氨酸 N6 在内的 11 个氨基，平均被取代掉 5 个。Mipeginterferon alfa-2b 的相对分子质量为 40 kDa。
T76168	Carboxypeptidase C
	CarboxypeptidaseC为生化研究中常用的羧肽酶，专门用于切除多肽链羧基末端的赖氨酸、精氨酸和脯氨酸，同时也能处理包含中性、脂肪族、芳香族及酸性蛋白质氨基酸的肽链。
T76376	Lys-Gln-Ala-Gly-Asp-Val
	Lys-Gln-Ala-Gly-Asp-Val (KQAGDV), 纤维蛋白原γ链(fibrinogen γ-chain)末端六个氨基酸组成，是细胞粘附肽。通过α2bβ3整合素，介导细胞粘附，对平滑肌细胞(SMCs)具有有效粘附配体功能。

化合物

Cat.No: T6829

Synonym: EPI001,EPI 001

Target: Apoptosis, Androgen Receptor, PPAR

Cat.No: TP1031

Synonym: Tetracosactrin,替可克肽

Target: Others

N-Acetyl-D-galactosamine

Cat.No: T5885

Synonym: GalNAc,2-乙酰胺基-2-脱氧-D-半乳糖

Target: Others

Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-

Cat.No: T40026

Synonym: 4-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]butanoic acid

Target: Others

Fibronectin Adhesion-promoting Peptide acetate

Cat.No: TP1153L

Synonym: Fibronectin Adhesion-promoting Peptide acetate(125720-21-0 free base),Heparin Binding Peptide acetate

Target: Others

c-Myc Peptide Trifluoroacetate

Cat.No: TP1315

Target: Others

IKKγ NBD Inhibitory Peptide acetate

Cat.No: TP1615L

Synonym: IKKγ NBD Inhibitory Peptide acetate(372146-18-4 free base)

Target: NF-κB

Cat.No: TP1197

Synonym: SQ19844,辛卡利特,CCK-8,Cholecystokinin octapeptide

Target: Others

Cat.No: TP1280

Target: Others

gamma-preprotachykinin amide (72-92) acetate

Cat.No: T9417L

Synonym: gamma-preprotachykinin amide (72-92) acetate (114882-65-4 Free base)

Target: Others

Thioredoxin reductase peptide acetate

Cat.No: TP1604L

Synonym: Thioredoxin reductase peptide acetate(950890-23-0 free base)

Target: Others

Cat.No: T32126

Cat.No: T25371

Synonym: Emd55450,Emd-55450

Secretin (28-54), human

Cat.No: TP1136

Synonym: Human secretin

N-(Amino-PEG5)-N-bis(PEG4-acid)

Cat.No: T16173

Target: Others

Chemerin-9, Mouse

Cat.No: T37128

9-(Boc-amino)nonanoic Acid

Cat.No: T71920

Carboxypeptidase B

Cat.No: T76102

14-(Fmoc-amino)-tetradecanoic acid

Cat.No: T70057

Caerulein, desulfated

Cat.No: TP1547

Neuronostatin-13 (human)

Cat.No: TP1827

Synonym: Neuronostatin-13 human

Fibronectin Adhesion-promoting Peptide

Cat.No: TP1153

Synonym: Heparin Binding Peptide

Cat.No: TP1448

Cat.No: T71906

β-Amyloid (1-9)

Cat.No: TP1645

Synonym: β-Amyloid 1-9

Cat.No: T71872

N-Boc-15-aminopentadecanoic acid

Cat.No: T70303

Boc-7-Aminoheptanoic acid

Cat.No: T71789

Fmoc-7-amino-heptanoic acid

Cat.No: T71970

[Tyr12] Somatostatin 28 (1-14)

Cat.No: T76459

Boc-10-Aminodecanoic acid

Cat.No: T71919

Fibronectin Adhesion-promoting Peptide TFA

Cat.No: TP1152

Synonym: Heparin Binding Peptide TFA

Angiogenin Fragment (108-123)

Cat.No: T83115

SNAP-25 187-203

Cat.No: TP1576

Transdermal Peptide TFA (918629-48-8 free base)

Cat.No: TP1032

Synonym: Transdermal Peptide TFA,TD 1 (peptide) (TFA)

Amyloid Precursor C-Terminal Peptide

Cat.No: TP2177

Target: Others

IKKγ NBD Inhibitory Peptide

Cat.No: TP1615

α-Neoendorphin (1-8)

Cat.No: TP1514

Synonym: α-Neoendorphin 1-8

Recombinant Proteinase K

Cat.No: T76202

Oxyntomodulin (human, mouse, rat)

Cat.No: T81585

Synonym: Proglucagon (33-69)

Gastric Inhibitory Polypeptide (1-30), porcine

Cat.No: T76308

Cat.No: T36876

Cat.No: TP1130

Synonym: CGRP-II (Human),Human β-CGRP

Cat.No: TP1944

Cat.No: T35827

Synonym: PKCε Inhibitor Peptide,Protein Kinase Cɛ Inhibitor Peptide,ɛV1-2

a-Bag Cell Peptide (1-7)

Cat.No: T83221

r8-Gly-Noxa A BH3

Cat.No: T80228

Mipeginterferon alfa-2b

Cat.No: T77087

Carboxypeptidase C

Cat.No: T76168

Lys-Gln-Ala-Gly-Asp-Val

Cat.No: T76376

Cat. No.	Product Name	Target	Signaling Pathways
T4757	L-Homoserine (S)-2-氨基-4-羟基丁酸,(S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID	Others; Endogenous Metabolite	Metabolism; Others
	L-Homoserine ((S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID) 是天然存在的非蛋白丝氨酸，是合成苏氨酸、蛋氨酸和赖氨酸的共有中间体。它是氨基酸丝氨酸的更具反应性的变体。
T4889	2,6-Diaminoheptanedioic acid	Others; Endogenous Metabolite	Metabolism; Others
	2,6-Diaminoheptanedioic acid 是内源性代谢产物的一种。

天然产物

Cat.No: T4757

Synonym: (S)-2-氨基-4-羟基丁酸,(S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID

Target: Others, Endogenous Metabolite

2,6-Diaminoheptanedioic acid

Cat.No: T4889

Target: Others, Endogenous Metabolite

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