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Cat. No.	Product Name	Target	Signaling Pathways
T23323	SB 611812	Neurotensin Receptor	GPCR/G Protein
	SB 611812 是 urotensin-II (UT) 的拮抗剂，可用于心血管疾病治疗的研究。
T2058	Palosuran ACT-058362	GPR	Endocrinology/Hormones; GPCR/G Protein
	Palosuran (ACT-058362) 是人类 UT 受体的新型强效特异性拮抗剂，对表达人重组受体的 CHO 细胞膜的IC50值为 3.6 nM。它可改善糖尿病大鼠的胰腺和肾脏功能。
T22476	(±)-AC 7954 hydrochloride	Neurotensin Receptor	GPCR/G Protein
	(±)-AC 7954 hydrochloride是一种urotensin-II (UT)受体激活剂。
T37527L	[Orn8]-Urotensin II acetate	GPR	Endocrinology/Hormones; GPCR/G Protein
	[Orn8]-Urotensin II acetate 是一种 Urotensin 受体配体和 Urotensin 受体的部分激动剂。
T27328	FL104 FL-104,FL 104	GPR	Endocrinology/Hormones; GPCR/G Protein
	FL104是小分子urotensin II 受体的有效激动剂，pEC50=7.11。
TP1928L1	[Orn5]-URP acetate [Orn5]-URP acetate(782485-03-4 free base)	GPR	Endocrinology/Hormones; GPCR/G Protein
	[Orn5]-URP acetate 是一种有效的选择性 Urotensin-II receptor (UT) 拮抗剂 (pEC50 = 7.24)。 [Orn5]-URP 没有激动剂活性。
TP2104L	UFP 803 acetate	Neurotensin Receptor	GPCR/G Protein
	UFP 803 acetate 是一种有效的 urotensin-II (UT) 受体配体。 UFP-803 显示较低残留激动剂的活性。
TP1737L	Urotensin II (114-124), human acetate Urotensin II (114-124), human acetate(251293-28-4 free base)	GPR	Endocrinology/Hormones; GPCR/G Protein
	Urotensin II (114-124), human acetate(251293-28-4 free base) 是一种 11 个氨基酸残基肽，是一种有效的血管收缩剂和孤儿受体 GPR14 的激动剂。
TP1199L	Urotensin I acetate (83930-33-0 Free base)	CRFR	GPCR/G Protein
	Urotensin I acetate 是一种 CRF 样神经肽，可作为 CRF 受体激动剂，对 CHO 细胞中的人 CRF1、人 CRF2 和大鼠 CRF2α 受体的 pEC50 分别为 11.46、9.36 和 9.85，对 CHO 细胞的 Kis 分别为 0.4、1.8 和 5.7 nM hCRF1、rCRF2α 和 mCRF2β 受体分别为。
TP2106L	Urantide acetate(669089-53-6 free base)	Neurotensin Receptor	GPCR/G Protein
	Urantide acetate(669089-53-6 free base) 是一种选择性和竞争性的 urotensin-II (UT) 受体拮抗剂 (pKB = 8.3)。体外阻断 hU-II 诱导的胸主动脉收缩。对去甲肾上腺素或内皮素 1 诱导的收缩或乙酰胆碱诱导的松弛没有影响。在钙动员测定（在表达 hUT 受体的 CHO 细胞中）中表现为部分激动剂。
T12848	SB-657510	Others; Neurotensin Receptor	GPCR/G Protein; Others
	SB-657510 是 urotensin II (UII) receptor (UT) 拮抗剂。对于人，猴，猫，大鼠和小鼠的UT 的 Ki 值分别为 61、17、30、65 和 56 nM。SB-657510 通过抑制 UII 诱导的人类血管内皮细胞中炎性介质，如粘附分子，使细胞因子和组织因子上调从而发挥抗炎作用。SB 657510对糖尿病小鼠模型中糖尿病相关动脉粥样硬化疾病具有治疗作用。
T23326	SB 706375	Others	Others
	urotensin-II (UT) receptor antagonist
T37527	[Orn8]-Urotensin II [Orn8]-Urotensin II
	[Orn8]-Urotensin II 是一种 Urotensin 受体配体和 Urotensin 受体的部分激动剂。
T28692	SB-436811 SB 436811
	SB-436811 is an antagonist of human urotensin-II receptor.
T26542	AC-7954
	AC-7954 is a potent and efficacious agonist of urotensin II receptor.
T71642	GSK-1562590
	GSK-1562590 is a urotensin-II receptor antagonist.
T22815	GSK 1562590 hydrochloride	Others	Others
	urotensin II (UT) receptor antagonist
T27441	GSK 1440115 GSK1440115,GSK-1440115
	GSK 1440115, an orally active urotensin II receptor antagonist, is used to treat asthma.
T75962	Urotensin II, mouse acetate
	Urotensin II, mouse acetate，是孤儿G蛋白偶联受体（GPR14或SENR）的一种内源性配体，具有显著的血管收缩活性并在中枢神经系统中发挥重要功能。
T75827	UFP-803 TFA
	UFP-803 TFA 是有效的urotensin-II receptor (UT)配体。UFP-803 TFA 具有较低的残留激动剂活性，因此它可以作为研究UT 系统在生理学和病理学中作用的重要工具。
TP1415	Urotensin II (114-124), human TFA
	Urotensin II (114-124), human TFA, is an 11-amino acid residue peptide with a strong vasoconstrictor effect. This compound acts as an agonist for the orphan receptor GPR14.
TP1737	Urotensin II (114-124), human
	Urotensin II (114-124), human, is an 11-amino acid residue peptide that exhibits strong vasoconstrictor activity and acts as an agonist for the orphan receptor GPR14.
T75828	[Orn5]-URP TFA
	[Orn5]-URP TFA 为Urotensin-II receptor (UT) 的有效且选择性纯拮抗剂，具pEC50值7.24，未呈现激动剂活性。
T36729	Urotensin II (goby) (trifluoroacetate salt)
	Urotensin II is a peptide vasoconstrictor and agonist of the urotensin (UT) receptor (Ki= 2.06 nM for the human recombinant receptor expressed in HEK293 cells).1It stimulates intracellular calcium mobilization in HEK293 cells expressing human and rat UT (EC50s = 0.47 and 0.78 nM, respectively) but decreases intracellular calcium concentration in goby (G. mirabilis) enterocytes when used at a concentration of 500 nM.2Urotensin II (20 mU/ml) stimulates active sodium and chloride absorption across ...
TP1199	Urotensin I Catostomus urotensin I
	Urotensin I is, 41-aa neuropeptide, acts as an agonist of CRF receptor with pEC50s of 11.46, 9.36 and 9.85 for human CRF1, human CRF2 and rat CRF2α receptors in CHO cells, and Kis of 0.4, 1.8, and 5.7 nM for hCRF1, rCRF2α and mCRF2β receptors, respectivel
TP1928	[Orn5]-URP
	Urotensin-II (UT) receptor pure antagonist (pEC50 = 7.24). Displays no agonist activity unlike other U-II/URP analogs. Inhibits the action of U-II in the rat aorta ring assay.
T75961	Urotensin II, mouse TFA
	Urotensin II, mouse TFA 为孤儿G蛋白偶联受体GPR14或SENR的内源性配体，具有强效血管收缩作用，并在中枢神经系统中发挥重要角色。
T29077	Urolinin nWWK-Tyr(3-NO2)-Abu
	Urolinin is a linear peptidic Urotensin-II Receptor Agonist with low nanomolar potency as well as improved metabolic stability. Urolinin is a hexameric UIIR agonist with an EC50 of 4.75 nM and a metabolic stability of 1319 min, 6.3-fold higher than wild-t
TP2106	Urantide
	Selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3). Blocks hU-II induced contractions in thoracic aorta ex vivo. Exhibits no effect on noradrenaline or endothelin 1-induced contraction or on acetylcholine-induced relaxation. Behav
TP2104	UFP-803 UFP 803
	Urotensin-II (UT) receptor ligand; behaves as a silent antagonist in most in vitro assays and in vivo, but does retain small residual agonist activity under certain conditions in some assays. Competitively antagonizes U-II induced contractions in the rat
T35814	Urocortin III (human) (trifluoroacetate salt)
	Urocortin III is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin II , frog sauvagine, and piscine urotensin I.1 Human urocortin III shares 90, 40, 37, and 21% identity to mouse urocortin III , mouse urocortin II , human urocortin , and mouse urocortin, respectively. Urocortin III selectively binds to type 2 CRF receptors (Kis = 21.7, 13.5, and >100 nM for rat CRF2α, rat CRF2β, and human CRF1, respectively)....

化合物

Cat.No: T23323

Target: Neurotensin Receptor

Cat.No: T2058

Synonym: ACT-058362

Target: GPR

(±)-AC 7954 hydrochloride

Cat.No: T22476

Target: Neurotensin Receptor

[Orn8]-Urotensin II acetate

Cat.No: T37527L

Target: GPR

Cat.No: T27328

Synonym: FL-104,FL 104

Target: GPR

[Orn5]-URP acetate

Cat.No: TP1928L1

Synonym: [Orn5]-URP acetate(782485-03-4 free base)

Target: GPR

UFP 803 acetate

Cat.No: TP2104L

Target: Neurotensin Receptor

Urotensin II (114-124), human acetate

Cat.No: TP1737L

Synonym: Urotensin II (114-124), human acetate(251293-28-4 free base)

Target: GPR

Urotensin I acetate (83930-33-0 Free base)

Cat.No: TP1199L

Target: CRFR

Urantide acetate(669089-53-6 free base)

Cat.No: TP2106L

Target: Neurotensin Receptor

Cat.No: T12848

Target: Others, Neurotensin Receptor

Cat.No: T23326

Target: Others

[Orn8]-Urotensin II

Cat.No: T37527

Synonym: [Orn8]-Urotensin II

Cat.No: T28692

Synonym: SB 436811

Cat.No: T26542

Cat.No: T71642

GSK 1562590 hydrochloride

Cat.No: T22815

Target: Others

Cat.No: T27441

Synonym: GSK1440115,GSK-1440115

Urotensin II, mouse acetate

Cat.No: T75962

Cat.No: T75827

Urotensin II (114-124), human TFA

Cat.No: TP1415

Urotensin II (114-124), human

Cat.No: TP1737

Cat.No: T75828

Urotensin II (goby) (trifluoroacetate salt)

Cat.No: T36729

Cat.No: TP1199

Synonym: Catostomus urotensin I

Cat.No: TP1928

Urotensin II, mouse TFA

Cat.No: T75961

Cat.No: T29077

Synonym: nWWK-Tyr(3-NO2)-Abu

Cat.No: TP2106

Cat.No: TP2104

Synonym: UFP 803

Urocortin III (human) (trifluoroacetate salt)

Cat.No: T35814

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