40
4
Cat. No. | Product Name | Target | Signaling Pathways |
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T83778 |
5-(3-Aminoallyl)uridine-5'-O-triphosphate sodium
AA-UTP,aminoallyl-UTP |
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aminoallyl-UTP(5-(3-氨基丙烯)尿苷-5'-O-三磷酸)是一种经过胺修饰的核苷酸,用于合成亲和标记的UTP。aminoallyl-UTP被用于合成互补RNA(cRNA)和细菌转移信使RNA(tmRNA)中,进而用于生成用于微阵列的荧光标记探针。 | |||
T79196 |
4-Thiouridine 5′-triphosphate tetralithium
4-Thio-UTP tetralithium |
P2Y Receptor | GPCR/G Protein; Neuroscience |
4-Thiouridine 5’-triphosphate (4-Thio-UTP) tetralithium 作为P2Y2和P2Y4受体的高效激动剂,其对hP2Y2的EC50为35 nM,对hP2Y4的EC50为350 nM。该化合物广泛应用于交联实验以及转录复合物标记研究。 | |||
T79197 |
4-Thiouridine 5′-triphosphate tetrasodium
4-Thio-UTP tetrasodium |
P2Y Receptor | GPCR/G Protein; Neuroscience |
4-Thiouridine 5′-triphosphate (4-Thio-UTP) tetrasodium 作为P2Y2和P2Y4受体的有效激动剂,显示出对hP2Y2的EC50为35 nM,以及对hP2Y4的EC50为350 nM。该化合物适用于交联实验和转录复合物标记研究。 | |||
T83840 |
Uridine-5'-O-(3-thiotriphosphate) sodium
UTP-γ-S |
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Uridine-5'-O-(3-thiotriphosphate) (UTP-γ-S) 是UTP的一种抗水解衍生物,是嘌呤P2Y2受体的激动剂。在表达人类P2Y2受体的1321N1星形胶质瘤细胞中,其可诱导肌醇磷酸盐的形成(EC50 = 240 nM),并且在来自囊性纤维化患者的原代鼻上皮细胞中以浓度依赖的方式诱导氯离子分泌。UTP-γ-S在分离的人类冠状动脉中诱导血管收缩(EC50 = 25.1 µM)。 | |||
T83822 |
Rp-Uridine-5'-O-(1-thiotriphosphate) sodium
Rp-UTP-α-S |
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Rp-Uridine-5'-O-(1-thiotriphosphate)(Rp-UTP-α-S)是一种核苷酸激动剂,针对嘌呤P2Y2和P2Y4受体。在表达P2Y2或P2Y4受体的1321N1星形胶质细胞中,它能够促进肌醇磷酸的积累(EC50s分别为5.4 和27 µM)。 | |||
T83823 |
Sp-Uridine-5'-O-(1-thiotriphosphate) sodium
Sp-UTP-α-S |
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Sp-Uridine-5'-O-(1-thiotriphosphate) (Sp-UTP-α-S) 是 purinergic Y2 (P2Y2) 和 P2Y4 受体的核苷酸激动剂。它在表达 purinergic P2Y2 或 P2Y4 受体的 1321N1 星形胶质瘤细胞中诱导肌醇磷酸累积(EC50s 分别为 14 和 81 µM)。 | |||
T75379 | Biotin-16-UTP | ||
Biotin-16-UTP作为RNA聚合酶的活性底物,在体外转录反应中可取代UTP进行RNA标记。 | |||
T82495 |
eGFP mRNA(N1-Me-Pseudo UTP)
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eGFP mRNA可以在哺乳动物细胞培养中直接表达出明亮的绿色荧光蛋白,该荧光蛋白源自水母Aequorea victoria,并在509 nm的激发光下发出绿色荧光。作为一种常用的报告蛋白,eGFP用于检测基因表达。 | |||
T82397 |
Firefly Luciferase mRNA(N1-Me-Pseudo UTP)
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Firefly luciferase mRNA可编码一种起源于Photinus pyralis(萤火虫)的荧光素酶。作为广泛运用于基因调控和功能研究的生物发光报告系统,Firefly luciferase适合进行基因表达、细胞活性以及活体成像等各类检测分析。 | |||
T75102 | COVID-19 Spike Protein mRNA(N1-Me-Pseudo UTP) | ||
COVID-19 Spike Protein mRNA 用于表达新型冠状病毒肺炎刺突蛋白,关键于 RNA 传递、翻译效率与细胞活力的检测。该蛋白定位于病毒膜表面,主导病毒与宿主细胞膜受体的结合及膜融合,促使 COVID-19 病毒入侵细胞。同时,它是宿主中和抗体作用的主要位点与疫苗开发的核心靶标。 | |||
T40770 |
5-Propargylamino-3'-azidomethyl-dUTP
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5-Propargylamino-3'-azidomethyl-dUTP is a nucleoside molecule. It finds applications in DNA synthesis and sequencing. | |||
T19150 |
5-BrUTP sodium salt
5-Bromouridine 5'-triphosphate sodium salt |
Others | Others |
5-BrUTP sodium salt can be used to label RNA to measure the transcription. | |||
T75385 | Tetramethylrhodamine-dUTP | ||
Tetramethylrhodamine-dUTP (TAMRA-dUTP) 用于 DNA 的末端标记。 | |||
T38528 |
5-Propargylamino-ddUTP
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5-Propargylamino-ddUTP is a nucleoside molecule employed for the synthesis of cyanine dye-nucleotide conjugates, commonly used in nucleic acid labeling and sequence analysis. | |||
T40970 |
Biotin-16-dUTP
Biotin-16-dUTP,Biotin-16-deoxyuridine-5'-triphosphate |
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Biotin-16-dUTP is a fluorescent substitute of dTTP. | |||
T75382 |
AMCA-6-dUTP
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AMCA-6-dUTP AMCA-6-dUTP 可用于 DNA/cDNA 的酶标记。 | |||
T39209 |
5-PA-dUTP
5-PA-dUTP,5-Propargylamino-dUTP |
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5-PA-dUTP (5-Propargylamino-dUTP) is a modified nucleotide, specifically designed with a C5 modification. It serves the purpose of being incorporated into DNA nanoparticles (DNPs) for the efficient delivery of photosensitizers. | |||
T19149 |
5-BrdUTP sodium salt
5-Bromo-2'-deoxyuridine 5'-triphosphate sodium salt |
Others | Others |
5-BrdUTP sodium salt is a TdT substrate that can be used to label the DNA double-strand breaks. | |||
T41104 |
dUTP sodium
2'-Deoxyuridine-5'-triphosphate sodium salt |
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dUTP sodium is used for PCR. | |||
T75341 |
Biotin-16-dUTP trisodium
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Biotin-16-dUTP trisodium(Biotin-16-deoxyuridine-5'-triphosphate trisodium)可以通过酶促方式掺入DNA/cDNA中,作为其天然对应物dTTP的替代品。这种化合物主要用于生产用于多种检测应用的生物素化DNA探针。储存条件需避光。 | |||
T40969 |
Biotin-11-dUTP
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Biotin-11-dUTP is a fluorescent substitute for dTTP. | |||
T22503 |
2-ThioUTP tetrasodium salt
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Others | Others |
2-ThioUTP tetrasodium salt is a P2Y2 agonist. | |||
T82597 |
ddUTP (lithium), 100mM in H2O
2',3'-Dideoxyuridine-5'-triphosphate lithium |
Nucleoside Antimetabolite/Analog | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
ddUTP (lithium), 100mM in H2O 是一种核酸类似物,能够被嵌入DNA、RNA或其他核酸分子中。此化合物可应用于DNA/RNA杂交实验,如Southern blots、Northern blots等。 | |||
T19173 |
AA-dUTP sodium salt
Aminoallyl-dUTP sodium salt |
Others | Others |
AA-dUTP sodium salt is a fluorescent dye which can be used to stain cDNA. | |||
T79579 |
ddUTP
2′,3′-Dideoxyuridine-5′-triphosphate |
Reverse Transcriptase | Microbiology/Virology |
ddUTP (2′,3′-Dideoxyuridine-5′-triphosphate) 作为HIV与AMV逆转录酶的选择性抑制剂,其Ki为0.05 µM及1 µM。ddUTP在dTTP位点掺入生长中的DNA链,从而抑制其进一步的链延伸。 | |||
T23499 |
UTPγS trisodium salt
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Others | Others |
P2Y2 and P2Y4 receptor agonist | |||
T28463 |
PSB-16133 sodium
PSB-16133,PSB16133,PSB 16133 |
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PSB-16133 is a potent and selective antagonist for the UTP-activated P2Y4 Receptor with IC50 value of 233 nM. | |||
T36299 |
Uridine triphosphate 13C9,15N2 sodium
Uridine triphosphate 13C9,15N2 sodium |
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Uridine triphosphate 13C9,15N2 (UTP 13C9,15N2) sodium, a labeled form of uridine triphosphate sodium, facilitates nucleic acid synthesis. | |||
T74176 | Pseudouridine 5'-triphosphate trisodium | ||
Pseudouridine 5'-triphosphate (Pseudo-UTP) 是聚合酶介导的 RNA 合成中常用的修饰核苷酸之一。与含有 UTP 的未修饰的 mRNA 相比,含Pseudo-UTP 的 mRNA 的显示出更好的核酸酶稳定性,免疫原性和翻译特性。 | |||
T83295 | 5-Azacytidine 5′-triphosphate sodium | ||
5-Azacytidine 5’-triphosphate sodium 为胞苷类似物,能在DNA依赖性RNA聚合酶反应中抑制[3H]CTP掺入,而不影响[3H]UTP的掺入。 | |||
T10677 | Carbodine | Others | Others |
Carbodine (Carbocyclic cytidine) is a broad-spectrum antiviral agent and targets CTP synthetase that converts UTP to CTP. It possesses significant antiviral activity against influenza virus types A0/PR-8/34 and A2/Aichi/2/68 in vitro. | |||
T75399 | GlcNAc 1-P uridyltransferase (CjGlmU) | ||
GlcNAc 1-P uridyltransferase (CjGlmU) 为一种糖核苷酸转移酶,以UTP和GlcNAc-1-P为天然底物,负责合成UDP-GlcNAc。此酶展现出潜在的抗菌活性分子研究价值。 | |||
T75398 | UDP-sugar pyrophosphorylase (BlUSP) | ||
UDP-sugar pyrophosphorylase (BlUSP) 是一种酶,其功能是将葡萄糖-1-磷酸(Glc-1-P)转化为UDP-葡萄糖(UDP-Glc)。该酶通过催化UTP的尿苷基到糖-1-磷酸的可逆转移,进而产生UDP-糖和焦磷酸(PPi)。 | |||
T36300 |
Uridine-5’-monophosphate (sodium salt hydrate)
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Uridine-5’-monophosphate (UMP) is a ribonucleotide.1It is formedviadecarboxylation of orotidine-5’-monophosphate (5’-OMP) by OMP decarboxylase. UMP is further phosphorylated by UMP-CMP kinase to form UDP and UTP during nucleic acid biosynthesis. Formulations containing UMP have been used as dietary supplements. 1.Berg, J.M., Tymoczko, J.L., and Stryer, L.Nucleotide BiosynthesisBiochemistry(2002) | |||
T35657 |
3'-Deoxyuridine-5'-triphosphate
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3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM[1]. 3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is synthesized starting from cordycepin in good yield. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA by the RNA polymerases. 3'-Deoxyuridine-5'-tri... | |||
T83296 |
5-Azacytidine 5′-triphosphate
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5-Azacytidine 5′-triphosphate (5-aza-CMP) 为一种胞苷类似物,可抑制 DNA 依赖性 RNA 聚合酶反响中的 [3H]CTP 并入 RNA,而不影响 [3H]UTP 的并入。 | |||
T35658 | 3'-Deoxyuridine-5'-triphosphate trisodium | ||
3'-Deoxyuridine-5'-triphosphate trisodium (3'-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate trisodium strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM[1]. 3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is synthesized starting from cordycepin in good yield. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA by the RNA polym... | |||
T78352 |
N-acetylglucosamine-1-P uridyltransferase (AGX1)
GlcNAc1pUT |
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N-acetylglucosamine-1-P uridyltransferase (AGX1) (GlcNAc1pUT) 是具有双功能乙酰转移酶/尿苷转移酶活性的原核生物专有酶。该酶能结合GlcNAc-1-P与UTP,催化合成UDP-GlcNAc的尿苷酰转移反应。 | |||
T40753 |
Cytidine-5'-triphosphate
Cytidine triphosphate,Cytidine-5'-triphosphate,5'-CTP |
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Cytidine 5'-triphosphate (5'-CTP), also known as cytidine triphosphate, is a nucleoside triphosphate that plays a crucial role as a building block for nucleotides and nucleic acids, as well as lipid biosynthesis. It is synthesized through the catalytic action of cytidine triphosphate synthase, which converts uridine 5'-triphosphate (UTP) to cytidine 5'-triphosphate. Cytidine 5'-triphosphate is an essential biomolecule in T. gondii's de novo pyrimidine biosynthetic pathway. | |||
T83270 |
6-Azauridine triphosphate
6-Azauridine 5′-triphosphate |
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6-Azauridine triphosphate(6-Azauridine 5′-triphosphate)为尿苷三磷酸(UTP)核苷酸类似物,应用于 RNA 合成和转录调控机制研究。 |
Cat. No. | Product Name | Target | Signaling Pathways |
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T8393 |
Uridine triphosphate trisodium salt
UTP, Trisodium Salt,Uridine 5'-triphosphate trisodium salt,尿苷-5'-三磷酸三钠盐,Uridine triphosphate (trisodium salt) |
Others | Others |
Uridine triphosphate trisodium salt (UTP, Trisodium Salt) 是一种核苷酸,在正常和疾病状态,均能够调节胰腺内分泌和外分泌、通道、增殖、转运体和细胞内信号传导的功能。 | |||
T7711 |
Uridine triphosphate
尿苷5'-三磷酸酯,UTP,Uridine 5'-triphosphate,三磷酸尿苷 |
Others; Endogenous Metabolite | Metabolism; Others |
Uridine triphosphate (Uridine 5'-triphosphate) 是一种核苷酸,调节胰腺内分泌和外分泌、增殖、通道、转运体和细胞内信号传导的功能。 | |||
T38427 |
dUTP trisodium
2'-Deoxyuridine-5'-triphosphate trisodium salt,Deoxyuridine triphosphate |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
dUTP trisodium (Deoxyuridine triphosphate) 是在 5'-位具有三磷酸基团的脱氧尿苷磷酸盐,可用于 PCR。 | |||
T3999 |
D(+)-Galactosamine hydrochloride
D-半乳糖胺盐酸盐,D-氨基半乳糖盐酸盐,D-Galactosamine HCl |
Others | Others |
D(+)-Galactosamine hydrochloride (D-Galactosamine HCl) 是一种被证实的实验毒素,它能够产生自由基及UTP 核苷酸的消耗导致肝损伤,中毒剂量会造成肾功能不全,而肾功能衰竭通常和终末期肝损伤有关。脂多糖/D-Galactosamine 诱导的急性肝损伤是一种已知的暴发性肝衰竭动物模型。 |