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Search Results for " tsg "

Targets Recommended: Others

3

抑制剂 & 化合物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T10809	CHPG	Others	Others
	CHPG is a selective agonist of mGluR5. In BV2 microglial cells, it attenuates SO2-induced oxidative stress and inflammation through the TSG-6/NF-κB pathway.
T10809L	CHPG hydrochloride CHPG hydrochloride(170846-74-9 Free base)	ERK; NF-κB; GluR	MAPK; Neuroscience; NF-κB
	CHPG hydrochloride 是 mGluR5 的选择性激动剂。
T10808	CHPG sodium salt	NF-κB; GluR	Neuroscience; NF-κB
	CHPG sodium salt 是 mGluR5 的选择性激动剂，可激活 ERK 和 Akt 信号通路。 CHPG 钠盐可用于创伤性脑损伤的研究。

化合物

Cat.No: T10809

Target: Others

CHPG hydrochloride

Cat.No: T10809L

Synonym: CHPG hydrochloride(170846-74-9 Free base)

Target: ERK, NF-κB, GluR

CHPG sodium salt

Cat.No: T10808

Target: NF-κB, GluR

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01816	Pentraxin 3 Protein, Human, Recombinant (His) TNFAIP5,pentraxin 3,PTX3,TSG-14	Human	HEK293 Cells
	Pentraxin-related protein PTX3, also known as Tumor necrosis factor alpha-induced protein 5, Tumor necrosis factor-inducible gene 14 protein, TSG-14, PTX3 and TNFAIP5, is a secreted protein that contains one pentaxin domain. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. Pentraxins are a family of evolutionarily conserved multifunctional pattern-recognition proteins characterized by a cycl...
TMPJ-01322	TWSG1 Protein, Human, Recombinant (His) TSG,Twisted Gastrulation Protein Homolog 1,TWSG1	Human	HEK293 Cells
	Twisted Gastrulation Protein Homolog 1 (TWSG1) is a 22 kDa secreted protein that belongs to the twisted gastrulation protein family. Human TWSG1 is synthesized as a 223 aa precursor that contains a 25 aa signal peptide and a 198 aa mature chain. TWSG1 may be involved in dorsoventral axis formation. TWSG1 seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors.TWSG1 can inhibit BMP activity by binding directly to B...
TMPY-02807	TWSG1 Protein, Mouse, Recombinant (His) Twg,Twsg1,9030422N06Rik,AW552143,twisted gastrulation homolo...	Mouse	HEK293 Cells
	TWSG1 belongs to the twisted gastrulation protein family. TWSG1 from different species are functionally equivalent. In contrast to Drosophila where TWSG1 expression is limited to early embryos, expression of TWSG1 is found throughout mouse and human development. Mutations in the TWSG1 gene cause at least some of the cells on the dorsal half of the embryo to adopt more ventral cell fates. This is thought to involve gradients of the signaling molecule decapentaplegic. TWSG1 may function as a bone ...
TMPH-03758	TSG101 Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an intera...
TMPJ-01352	THSD1 Protein, Human, Recombinant (His) Transmembrane Molecule with Thrombospondin Module,TMTSP,Thro...	Human	HEK293 Cells
	Thrombospondin Type-1 Domain-Containing Protein 1 (THSD1) is a single-pass type I membrane protein. THSD1 contains a signal peptide and one TSP type-1 domain that is found in thrombospondin. THSD1 is a good novel candidate for TSG as it has been mapped to 13q14. Alternatively spliced transcript variants encoding distinct isoforms have been observed. THSD1 may be involved in the complement pathway.
TMPJ-00981	PTX3 Protein, Mouse, Recombinant (His) alpha-induced protein 5,pentraxin 3, long,pentaxin-related g...	Mouse	HEK293 Cells
	Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. It’s subunit is a disulfide-linked homooctamer that binds to C1q. PTX3 concentration is elevated in the joint fluid of patients with rheumatoid arthritis (RA), indicating that PTX3 may be a potential mediator...
TMPY-04417	DAPK1 Protein, Human, Recombinant (aa 1-363, His & GST) DAPK,death-associated protein kinase 1,ROCO3	Human	Baculovirus Insect Cells
	Death-associated protein kinase 1, also known as DAP kinase 1, DAPK1 and DAPK, is a cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser / Thr protein kinase family and DAP kinase subfamily. DAPK1 contains tenANK repeats, onedeath domain and oneprotein kinase domain. DAPK1 is a calcium / calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis. DAPK1 gene is a candidate tumor suppressor (TSG) and the abnormal methylation of DAPK1 g...

重组蛋白

Pentraxin 3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01816

Species: Human

Expression System: HEK293 Cells

TWSG1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01322

Species: Human

Expression System: HEK293 Cells

TWSG1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02807

Species: Mouse

Expression System: HEK293 Cells

TSG101 Protein, Human, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-03758

Species: Human

Expression System: E. coli

THSD1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01352

Species: Human

Expression System: HEK293 Cells

PTX3 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00981

Species: Mouse

Expression System: HEK293 Cells

DAPK1 Protein, Human, Recombinant (aa 1-363, His & GST)

Cat.No: TMPY-04417

Species: Human

Expression System: Baculovirus Insect Cells

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