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Cat. No.	Product Name	Target	Signaling Pathways
T6672	Sitaxsentan sodium 西他生坦钠,TBC11251 sodium salt,TBC11251,Thelin,Sitaxentan sodium	Endothelin Receptor	GPCR/G Protein
	Sitaxsentan sodium (TBC11251 sodium salt) 是 endothelin A receptor 选择性拮抗剂。
T1006	Propantheline bromide Neopepulsan,溴丙胺太林,Pro-Banthine,Neometantyl	AChR	Neuroscience
	Propantheline bromide (Pro-Banthine) 是一种抗毒蕈碱剂，用于研究多汗症，遗尿，胃肠和膀胱痉挛。
T19309L1	Endothelin 1 (swine, human) acetate Endothelin 1 (swine, human) acetate(117399-94-7 free base)	Endothelin Receptor	GPCR/G Protein
	Endothelin 1 (swine, human) acetate(117399-94-7 free base) 是一种合成肽，其序列为人和猪内皮素 1。它是一种有效的内源性血管收缩剂，通过两种类型的受体 ETA 和 ETB 起作用。
T22540L	Ac-Endothelin-1 (16-21), human acetate	Others	Others
	Ac-Endothelin-1 (16-21), human acetate 是内皮素家族的主要肽，已被证明在血管和非血管组织中具有多种生物活性。 C-末端片段是 ET 家族肽中高度保守的序列，已显示可区分称为 ETA 和 ETB 的两种 ET 受体亚型，因为它仅激活后者。
TP1174	Endothelin-2 (49-69), human Human endothelin-2,Endothelin-2, human,Endothelin-2 (human, canine),人内皮素2	Others	Others
	Endothelin-2 (49-69), human (Human endothelin-2) 是一种由 21 个氨基酸组成的血管活性肽。它可与 G 蛋白连接的跨膜受体，ET-RA 和ET-RB 结合。
TP2143	Endothelin-2 (49-69), human TFA Endothelin-2 (49-69) (human, canine) TFA,Human endothelin-2 TFA	Others	Others
	Endothelin-2 (49-69), human (TFA) is a 21-amino acid vasoactive peptide that binds to ET-RA and ET-RB.
T19309	Endothelin 1 (swine, human)	Others	Others
	Endothelin 1 (swine, human), a synthetic peptide mirroring the sequence of both human and swine Endothelin 1, functions as a robust endogenous vasoconstrictor by interacting with two receptor types, ETA and ETB.
T82886	Big endothelin-1 (rat 1-39)
	Big endothelin-1 (rat 1-39) 是一个由39个氨基酸残基组成的多肽。它能在清醒状态的Sprague-Dawley大鼠中诱导利尿和利钠的反应，并可导致小鼠血压上升。
T76329	[Asn18] Endothelin-1, human
	[Asn18] Endothelin-1, human 为一种多肽，属于内皮素家族中的主要亚型，关键于血管功能调节。
T76564	Endothelin-1 (1-31) (Human)
	Endothelin-1 (1-31) (Human) 是源于chymase对大ET-1选择性水解而来的有效血管收缩剂和血压升高剂。
T75731	Endothelin 1 (swine, human) (TFA)
	Endothelin 1 (swine, human) (TFA) 是具有人和猪内皮素 1 序列的合成肽，是有效的内源性血管收缩剂。Endothelin 1 通过两种类型受体 ETA 和 ETB 发挥作用。
T78063	Endothelin-1 (1-31) (Human) TFA	ERK	MAPK
	Endothelin-1 (1-31) (Human) TFA 是源自chymase对大ET-1选择性水解的一种有效血管收缩剂和血压升高剂。
T33314	Methantheline Bromide Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide
	Methantheline Bromide is a synthetic spasmolytic used to relieve cramps or spasms of the stomach, bowel, and bladder. It is also useful for intestinal or gastric ulcers (peptic ulcer disease), intestinal problems, pancreatitis, gastritis, biliary dysmotil
T76305	[Ala2] Endothelin-3, human
	[Ala2] Endothelin-3, human 为ET-3的线性类似物，其结构中的Cys残基被Ala所替代。ET-3是由人体横纹肌肉瘤细胞系产生，且仅在此细胞系中表达的一种具有血管活性的肽。在非肌肉来源的肉瘤细胞系中不表达。该肽能够作为旁分泌因子，促进内皮细胞迁移。
TP1175	Endothelin-3, human, mouse, rabbit, rat Endothelin 3 (Rat,Human)
	Endothelin-3, human, mouse, rabbit, rat , is a cyclic 21 amino acid peptide. It is an endogenous neuropeptide and potent vasoconstrictor.
T76081	Endothelin 1 (swine, human), Alexa Fluor 488-labeled
	Endothelin 1 (swine, human), Alexa Fluor 488-labeled 是标记了488 荧光的 Endothelin 1 合成肽。Endothelin 1 (swine, human) 是具有人和猪内皮素 1 序列的合成肽，是有效的内源性血管收缩剂。Endothelin 1 通过两种类型受体 ETA 和 ETB 发挥作用。
TP1512	[Ala1,3,11,15]-Endothelin TFA
	[Ala1,3,11,15]-Endothelin (TFA) is a highly selective for endothelin A (ETA) and endothelin B (ETB) receptor.[Ala1,3,11,15]-Endothelin is a selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ET
T76564L	Endothelin-1 (1-31) (Human) acetate
	Endothelin-1 (1-31) (Human) acetate，源自于chymase对大ET-1的选择性水解，是一种有效的血管收缩剂和血压升高剂。
T75772	[Ala1,3,11,15]-Endothelin (53-63) (TFA)
	[Ala1,3,11,15]-Endothelin (53-63) (TFA) 是一种ETB 激动剂。[Ala1,3,11,15]-Endothelin (53-63) (TFA) 对 ETB 具有选择性，IC50值范围为 0.33 nM 至 0.61 nM。[Ala1,3,11,15]-Endothelin (53-63) (TFA) 可用于血管收缩的研究。
T61453	Propantheline
	Propantheline is an orally active antagonist of muscarinic acetylcholine receptors (mAChRs), commonly employed to investigate smooth muscle dysfunction, hyperhidrosis, smooth muscle spasms or cramps in the stomach, intestines, or bladder, as well as involuntary urination [1] [2] [3].
TP2099	[Ala1,3,11,15]-Endothelin
	Selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ETB and ETA receptors respectively).
T36479	Big Endothelin-1 (1-38), human
	Human Big ET-1 comprises residues 53-90 of the endothelin precursor (preproendothelin). Compared to the mature endothelin-1 (hET-1), the peptide show less vasoconstrictor activity in vitro, but similar pressor effects in vivo. Former CAS-number 121014-53-7.
TP1173	Endothelin 3 (Rat,Human) (TFA) Endothelin-3, human, mouse, rabbit, rat TFA
	Endothelin-3, human, mouse, rabbit, rat TFA is a 21-amino acid vasoactive peptide that specifically interacts with G-protein-linked transmembrane receptors, ET-RA and ET-RB.
T36480	Big Endothelin-1 (1-39), porcine
	The big endothelins comprise residues 53-90 (human big ET-1) and 53-91 (porcine big ET-1) of the endothelin precursor (preproendothelin). Compared to the mature endothelin-1 (ET-1), both peptides show less vasoconstrictor activity in vitro, but similar pressor effects in vivo. Former CAS-number 121014-54-8.
TP2246	Endothelin-1 (1-15), amide, human	Others	Others
	Endothelin-1 is one of the there isoforms of endothelin (identified as ET-1, -2, -3) with varying regions of expression and binding to at least four known endothelin receptors, ETA, ETB1, ETB2 and ETC.
T22540	Ac-Endothelin-1 (16-21), human	Others	Others
	ENDOTHELIN-1 (ET-1), the principal peptide of the endothelin family, has been shown to have a variety of biological activities in both vascular and nonvascular tissues. The C-terminal fragment, which is a highly conserved sequence in the peptides of t

化合物

Sitaxsentan sodium

Cat.No: T6672

Synonym: 西他生坦钠,TBC11251 sodium salt,TBC11251,Thelin,Sitaxentan sodium

Target: Endothelin Receptor

Propantheline bromide

Cat.No: T1006

Synonym: Neopepulsan,溴丙胺太林,Pro-Banthine,Neometantyl

Target: AChR

Endothelin 1 (swine, human) acetate

Cat.No: T19309L1

Synonym: Endothelin 1 (swine, human) acetate(117399-94-7 free base)

Target: Endothelin Receptor

Ac-Endothelin-1 (16-21), human acetate

Cat.No: T22540L

Target: Others

Endothelin-2 (49-69), human

Cat.No: TP1174

Synonym: Human endothelin-2,Endothelin-2, human,Endothelin-2 (human, canine),人内皮素2

Target: Others

Endothelin-2 (49-69), human TFA

Cat.No: TP2143

Synonym: Endothelin-2 (49-69) (human, canine) TFA,Human endothelin-2 TFA

Target: Others

Endothelin 1 (swine, human)

Cat.No: T19309

Target: Others

Big endothelin-1 (rat 1-39)

Cat.No: T82886

[Asn18] Endothelin-1, human

Cat.No: T76329

Endothelin-1 (1-31) (Human)

Cat.No: T76564

Endothelin 1 (swine, human) (TFA)

Cat.No: T75731

Endothelin-1 (1-31) (Human) TFA

Cat.No: T78063

Target: ERK

Methantheline Bromide

Cat.No: T33314

Synonym: Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide

[Ala2] Endothelin-3, human

Cat.No: T76305

Endothelin-3, human, mouse, rabbit, rat

Cat.No: TP1175

Synonym: Endothelin 3 (Rat,Human)

Endothelin 1 (swine, human), Alexa Fluor 488-labeled

Cat.No: T76081

[Ala1,3,11,15]-Endothelin TFA

Cat.No: TP1512

Endothelin-1 (1-31) (Human) acetate

Cat.No: T76564L

[Ala1,3,11,15]-Endothelin (53-63) (TFA)

Cat.No: T75772

Cat.No: T61453

[Ala1,3,11,15]-Endothelin

Cat.No: TP2099

Big Endothelin-1 (1-38), human

Cat.No: T36479

Endothelin 3 (Rat,Human) (TFA)

Cat.No: TP1173

Synonym: Endothelin-3, human, mouse, rabbit, rat TFA

Big Endothelin-1 (1-39), porcine

Cat.No: T36480

Endothelin-1 (1-15), amide, human

Cat.No: TP2246

Target: Others

Ac-Endothelin-1 (16-21), human

Cat.No: T22540

Target: Others

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