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Search Results for " tgfβ1 "

Targets Recommended: TGF-beta/Smad

15

抑制剂 & 化合物

18

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T61389	TGFβ1-IN-1	TGF-beta/Smad	Stem Cells
	TGFβ1-IN-1 是一种具有口服活性的 TGF-β1 抑制剂，抑制 TGF-β1 诱导的纤维化标志物（α-SMA 和纤连蛋白）的产生，可用于研究癌症和自身免疫疾病。
T75004	TGFβ1-IN-2	Others	Others
	TGFβ1-IN-2，一种二芳基酰基腙衍生物，有效抑制成纤维细胞活化与增殖，常用于特发性肺纤维化(IPF)研究。
T75005	TGFβ1-IN-3	Others	Others
	TGFβ1-IN-3 是一种二芳基酰基腙衍生物，对成纤维细胞的活化和增殖有抑制作用。TGFβ1-IN-3 是治疗特发性肺纤维化 (IPF) 的候选化合物。
T7425	RU-301	TAM Receptor	Tyrosine Kinase/Adaptors
	RU-301 是一种新型 pan-TAM 受体抑制剂，能够在 TAM 的 Gas6 和 Ig1 结构域之间的界面处结合发挥 pan-TAM 抑制活性，Kd=12 μM，IC50=10 μM。
T60596	TGFβ-IN-1
	TGFβ-IN-1一种通过抑制转化生长因子β信号通路的抗肿瘤生长和转移剂。
T74163	TGFβR-IN-1
	TGFβR-IN-1 是一种长效肿瘤激活的TGFβR 抑制剂的前体。
T76066	pm26TGF-β1 peptide
	pm26TGF-β1 peptide为模拟人TGF-β1分子的肽，对TGF-β1受体展现高亲和力。该肽显示出有效抗炎特性，无嗜中性粒细胞的趋化性。
T76066L	pm26TGF-β1 peptide TFA
	pm26TGF-β1 peptide TFA 是模拟人类TGF-β1分子的肽，对TGF-β1受体有高亲和力。该化合物具备显著的抗炎性能，不引起嗜中性粒细胞的趋化现象。
T76681	Fresolimumab GC1008	TGF-beta/Smad	Stem Cells
	Fresolimumab (GC1008) 是一种具有特异性的人抗转化生长因子 β单克隆抗体，可与人 TGFβ1、TGFβ2 和 TGFβ3 的活性形式结合，可用于研究成人局灶节段性肾小球硬化和癌症。
T11052L	Disitertide acetate P144 acetate,Disitertide acetate(272105-42-7 Free base)	TGF-beta/Smad	Stem Cells
	Disitertide acetate (P144 acetate) 是转化生长因子 TGFβ1 的多肽抑制剂，特异性的阻断其与受体间的相互作用。Disitertide acetate 也是PI3K 的抑制剂和凋亡 (apoptosis) 诱导剂。
T76819	Metelimumab
	Metelimumab (CAT-192) 是一种人的IgG4单克隆抗体，可以选择性中和TGFβ1。
T77067	Livmoniplimab
	Livmoniplimab (ABBV-151; ARGX-115) 是一种有效的人源化抗 LRRC32 (GARP)/TGFβ1 单克隆抗体。Livmoniplimab 阻断 LRRC32 介导的潜在 TGFβ1 激活。Livmoniplimab 具有癌症研究的潜力。
T81931	Linavonkibart
	Linavonkibart (SRK 181) 是高亲和性全人源化抗体, 能选择性结合TGFβ1并阻断其活化。该化合物在癌症治疗中扮演关键角色。
T75717	Disitertide diammonium
	Disitertide (P144) diammonium 是转化生长因子TGFβ1的多肽抑制剂，特异性的阻断其与受体间的相互作用。Disitertide diammonium 也是PI3K 的抑制剂和凋亡 (apoptosis) 诱导剂。
T75716	Disitertide TFA
	Disitertide (P144) TFA 是转化生长因子TGFβ1的多肽抑制剂，特异性的阻断其与受体间的相互作用。Disitertide TFA 也是PI3K 的抑制剂和凋亡 (apoptosis) 诱导剂。

化合物

Cat.No: T61389

Target: TGF-beta/Smad

Cat.No: T75004

Target: Others

Cat.No: T75005

Target: Others

Cat.No: T7425

Target: TAM Receptor

Cat.No: T60596

Cat.No: T74163

pm26TGF-β1 peptide

Cat.No: T76066

pm26TGF-β1 peptide TFA

Cat.No: T76066L

Cat.No: T76681

Synonym: GC1008

Target: TGF-beta/Smad

Disitertide acetate

Cat.No: T11052L

Synonym: P144 acetate,Disitertide acetate(272105-42-7 Free base)

Target: TGF-beta/Smad

Cat.No: T76819

Cat.No: T77067

Cat.No: T81931

Disitertide diammonium

Cat.No: T75717

Disitertide TFA

Cat.No: T75716

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00500	Latent TGF beta 1 Protein, Mouse, Recombinant (His) transforming growth factor, beta 1,TGF β1,Tgfb-1,TGF-beta1,转...	Mouse	HEK293 Cells
	Latent TGF beta 1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P04202.
TMPY-05313	Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated transforming growth factor, beta 1,transforming growth facto...	Mouse	HEK293 Cells
	Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P04202.
TMPY-03945	Latent TGF beta 1 Protein, Rat, Recombinant (His) TGF β1,transforming growth factor, β1,transforming growth fa...	Rat	HEK293 Cells
	Latent TGF beta 1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P17246.
TMPY-00608	TGF beta 1 Protein, Rat/Mouse, Recombinant transforming growth factor, beta 1,transforming growth facto...	Mouse,Rat	HEK293 Cells
	TGF beta 1 Protein, Rat/Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 12.8 kDa.
TMPY-04211	Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His) transforming growth factor, β1,TGF β1,transforming growth fa...	Cynomolgus	HEK293 Cells
	Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa.
TMPJ-00249	TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated TGF-Beta-1,TGFB1,Transforming Growth Factor β-1,Latency-Asso...	Human	HEK293 Cells
	Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family...
TMPY-01133	Latent TGF beta 1 Protein, Human, Recombinant (His) CED,DPD1,transforming growth factor, beta 1,TGF β1,LAP,转化生长因...	Human	HEK293 Cells
	Latent TGF beta 1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is A0A499FJK2.
TMPY-02638	TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant transforming growth factor, beta 1,转化生长因子,transforming growt...	Human,Rhesus,Cynomolgus,Canine	CHO Cells
	TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 12.8 kDa and the accession number is A0A499FJK2.
TMPJ-00771	TGF beta 1 Protein, Mouse/Rat, Recombinant TGFB,TGFbeta,CEDLAP,TGF-beta-1,TGF-beta 1 protein,latency-as...	Mouse,Rat	HEK293 Cells
	Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II)...
TMPJ-00622	Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) 转化生长因子,Transforming growth factor β-1,Latent TGF-β1,TGFB,TGF...	Cynomolgus	HEK293 Cells
	Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 11 and 35-45 KDa and the accession number is F7HCV5.
TMPH-00305	TGF-beta 1 Protein, Bovine, Recombinant (His)	Bovine	E. coli
	TGF-beta 1 Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.8 kDa and the accession number is P18341.
TMPY-00229	Latent TGF beta 1 Protein, Canine, Recombinant (His) transforming growth factor, β1,transforming growth factor, b...	Canine	HEK293 Cells
	Latent TGF beta 1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.4 kDa.
TMPY-05521	Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated TGFB,TGF β1,转化生长因子,TGF-beta 1,transforming growth factor, be...	Human	HEK293 Cells
	Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is A0A499FJK2.
TMPH-00382	TGF-beta 1 Protein, Chicken, Recombinant (His & SUMO)	Chicken	E. coli
	TGF-beta 1 Protein, Chicken, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 29.0 kDa and the accession number is P09531.
TMPY-06355	Latent TGF beta 1 & GARP Heterotrimer Protein, Human, Recombinant (His) 转化生长因子,TGF β1 & GARP Heterotrimer	Human	HEK293 Cells
	Latent TGF beta 1 & GARP Heterotrimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 108.72 kDa and the accession number is P01137.
TMPJ-00250	LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated transforming growth factor β1,TGFβ,CED,TGFB,TGFbeta,LAP (TGF...	Human	HEK293 Cells
	Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFβ gene product. Extracellular activation of these complexes is a critical step in regulation of TGFβ function in vivo. The TGFβ1 LAP is a ligand for the integrin αvβ6 and that αvβ6-expressing cells induce spatially restricted activition of TGFβ1. And LAP identifies a novel CD4+/CD25+ regulatory T cell subset with ...
TMPJ-00772	Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated Transforming growth factor β-1,Latent TGF-β1,TGFB1,Transform...	Mouse	HEK293 Cells
	Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 13 and 35-45 KDa and the accession number is P04202.
TMPY-03861	Amelotin Protein, Human, Recombinant (mFc) amelotin,UNQ689	Human	HEK293 Cells
	Amelotin (AMTN) is a tooth enamel protein which is expressed in maturation-stage ameloblasts and also in the internal basal lamina of junctional epithelium, a unique epithelial structure attached to the tooth surface which protects against the constant microbiological challenge to the periodontium. TNF-α stimulates AMTN gene transcription in human gingival epithelial cells via C/EBP1, C/EBP2, and YY1 elements in the human AMTN gene promoter.AMTN mRNA levels increased at 6 h and reached maximum a...

重组蛋白

Latent TGF beta 1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00500

Species: Mouse

Expression System: HEK293 Cells

Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated

Cat.No: TMPY-05313

Species: Mouse

Expression System: HEK293 Cells

Latent TGF beta 1 Protein, Rat, Recombinant (His)

Cat.No: TMPY-03945

Species: Rat

Expression System: HEK293 Cells

TGF beta 1 Protein, Rat/Mouse, Recombinant

Cat.No: TMPY-00608

Species: Mouse,Rat

Expression System: HEK293 Cells

Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-04211

Species: Cynomolgus

Expression System: HEK293 Cells

TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated

Cat.No: TMPJ-00249

Species: Human

Expression System: HEK293 Cells

Latent TGF beta 1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01133

Species: Human

Expression System: HEK293 Cells

TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant

Cat.No: TMPY-02638

Species: Human,Rhesus,Cynomolgus,Canine

Expression System: CHO Cells

TGF beta 1 Protein, Mouse/Rat, Recombinant

Cat.No: TMPJ-00771

Species: Mouse,Rat

Expression System: HEK293 Cells

Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPJ-00622

Species: Cynomolgus

Expression System: HEK293 Cells

TGF-beta 1 Protein, Bovine, Recombinant (His)

Cat.No: TMPH-00305

Species: Bovine

Expression System: E. coli

Latent TGF beta 1 Protein, Canine, Recombinant (His)

Cat.No: TMPY-00229

Species: Canine

Expression System: HEK293 Cells

Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05521

Species: Human

Expression System: HEK293 Cells

TGF-beta 1 Protein, Chicken, Recombinant (His & SUMO)

Cat.No: TMPH-00382

Species: Chicken

Expression System: E. coli

Latent TGF beta 1 & GARP Heterotrimer Protein, Human, Recombinant (His)

Cat.No: TMPY-06355

Species: Human

Expression System: HEK293 Cells

LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00250

Species: Human

Expression System: HEK293 Cells

Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00772

Species: Mouse

Expression System: HEK293 Cells

Amelotin Protein, Human, Recombinant (mFc)

Cat.No: TMPY-03861

Species: Human

Expression System: HEK293 Cells

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