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Search Results for " stilbene "

17

抑制剂 & 化合物

15

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T71565	MOA-stilbene
	MOA-stilbene, also known as 3-Methoxy-2-(2-styrylphenyl)propenic acid methyl ester, is a fluorescence inhibitor. MOA-stilbene is a new tool for investigation of the reactions of the chloroplast cytochrome bf complex. MOA-stilbene is known to be a specific inhibitor of the Qo site of mammalian cytochrome bc 1 complex.
T71563	10-oxo-12(Z)-Octadecenoic Acid
	10-oxo-12(Z)-Octadecenoic acid is a metabolite of linoleic acid and an activator of transient receptor potential vanilloid 1 (TRPV1) and selectively increases calcium levels in HEK293 cells expressing TRPV1.
T0598	Iminostilbene 亚氨基芪,Dibenzazepine	Others	Others
	Iminostilbene (Dibenzazepine) 是 carbamazepine 的化学前体，主要用于治疗癫痫和神经性疼痛。
T123970	3,3',5,5'-Tetrahydroxy-4-methoxystilbene
	3,3',5,5'-Tetrahydroxy-4-methoxystilbene 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T123970，CAS号为 89946-11-2。
T60301	(Z)-p-cyano-α-Cyanostilbene
	(Z)-p-cyano-α-Cyanostilbene (compound 11) 是一种 phenantrene 衍生物，具有抗增殖活性。(Z)-p-cyano-α-Cyanostilbene 对 HeLa (IC50=0.21 μM) 和 HepG2 (IC50=0.230 μM) 细胞显示出显着的选择性，对正常皮肤成纤维细胞没有细胞毒性 (IC50>100 μM)。
T83326	4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium
	4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium 是荧光染料，用于逆行轴突运输二抗标记显示和全细胞荧光染色。
T60244	(Z)-α-Cyanostilbene
	(Z)-α-Cyanostilbene (化合物 8)，是一种双氰基取代的丙烯腈，对 HeLa 和 HepG2 细胞显示出选择性的抗增殖活性，IC50值分别为 0.33 和 0.52 μM。
T124035	Cajaninstilbene acid
	Cajaninstilbene acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124035，CAS号为 87402-84-4。
T81353	Pterostilbene-isothiocyanate PTER-ITC
	Pterostilbene-isothiocyanate (PTER-ITC) 在体外展现出显著的抗癌活性。它通过干扰β-catenin/TCF-4的相互作用，从而针对人骨肉瘤细胞发挥作用。
T60302	4,4'-Dicyanostilbene
	4,4'-Dicyanostilbene (化合物 43) 是一种有效的抗疟药，可抗 Dd2 菌株，EC50值为 27 nM。4,4'-Dicyanostilbene 对耐甲氧西林金黄色葡萄球菌具有体内功效。
T125873	(Z)-3-Hydroxy-5-methoxystilbene
	(Z)-3-Hydroxy-5-methoxystilbene 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125873。
T3643	HMN-176	PLK	Cell Cycle/Checkpoint
	HMN176 是一种二苯乙烯衍生物，可抑制有丝分裂，干扰 polo 样激酶-1 (PLK1)
T125462	Gnetifolin K GnetifolinK
	Gnetifolin K (GnetifolinK) 是一种来自 Gnetum parvifolium 的新型二苯乙烯二葡萄糖苷，具有潜在的神经保护活性，可用于研究DNA损伤。
T11284	FIDAS-3	Others; Wnt/beta-catenin; Methionine Adenosyltransferase (MAT)	Chromatin/Epigenetic; Cytoskeletal Signaling; Others; Stem Cells
	FIDAS-3 是一种强效Wnt 抑制剂，也是一种二苯乙烯衍生物，对甲硫氨酸腺苷转移酶 2A (MAT2A) 的IC50为 4.9 μM。它能够与 S-腺苷甲硫氨酸有效竞争MAT2A 结合，并具有抗癌作用。
T35986	CAY10512
	The nuclear factor-κB (NF-κB) regulates the expression of numerous genes involved in immunity and inflammation, cellular stress responses, growth, and apoptosis. Resveratrol, a polyphenolic trans-stilbene, is a known inhibitor of the activation of NF-κB and exhibits activity against a wide variety of cancer cells. CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNFα-induced activatio...
T31857	Fosbretabulin [free base] Fosbretabulin,Combretastatin A-4,CA4DP
	Fosbretabulin is a natural cis-stilbene that interferes with cellular tubulin dynamics and selectively destroys tumor blood vessels.
T36610	(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine
	(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine (CSTMP) is a stilbene derivative with antioxidant and anticancer activities. It stimulates proliferation of hydrogen peroxide-damaged ECV-304 cells (EC50 = 24.9 nM). CSTMP reduces hydrogen peroxide-induced release of lactate dehydrogenase (LDH) in and increases viability of human umbilical vein endothelial cells (HUVECs) in a concentration-dependent manner via inhibition of apoptosis. It reverses hydrogen peroxide-induced release of malondialdehyde ...

化合物

Cat.No: T71565

10-oxo-12(Z)-Octadecenoic Acid

Cat.No: T71563

Cat.No: T0598

Synonym: 亚氨基芪,Dibenzazepine

Target: Others

3,3',5,5'-Tetrahydroxy-4-methoxystilbene

Cat.No: T123970

(Z)-p-cyano-α-Cyanostilbene

Cat.No: T60301

4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium

Cat.No: T83326

(Z)-α-Cyanostilbene

Cat.No: T60244

Cajaninstilbene acid

Cat.No: T124035

Pterostilbene-isothiocyanate

Cat.No: T81353

Synonym: PTER-ITC

4,4'-Dicyanostilbene

Cat.No: T60302

(Z)-3-Hydroxy-5-methoxystilbene

Cat.No: T125873

Cat.No: T3643

Target: PLK

Cat.No: T125462

Synonym: GnetifolinK

Cat.No: T11284

Target: Others, Wnt/beta-catenin, Methionine Adenosyltransferase (MAT)

Cat.No: T35986

Fosbretabulin [free base]

Cat.No: T31857

Synonym: Fosbretabulin,Combretastatin A-4,CA4DP

(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine

Cat.No: T36610

Cat. No.	Product Name	Target	Signaling Pathways
TN2282	trans-Stilbene 反式-1,2二苯乙烯,1,2-Diphenylethylene (trans),(E)-Stilbene	Others	Others
	trans-Stilbene (1,2-Diphenylethylene (trans)) 可用于制备荧光增白剂、染料激光器、非甾体合成雌激素。
T3330	trans-Trimethoxyresveratrol trans-trismethoxy Resveratrol,E-Resveratrol Trimethyl Ether,MR-3,Tri-O-methylresveratrol,白藜芦醇三甲醚,3,4',5-Trimethoxy-trans-stilbene,Trimethoxystilbene	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	trans-Trimethoxyresveratrol (MR-3) 是一种 Resveratrol(RSV) 的衍生物，与Resveratrol(RSV)相比，它可能是一个更有效的抗炎、抗血管新生的化合物。
T3755	Pinostilbene	Others	Others
	Pinostilbene 是一种 Pterostilbene 的主要代谢物，能够抑制结肠癌细胞。
T4956	Tetrahydroxystilbene-2-O-β-D-glucoside tetrahydroxyl diphenylethylene-2-o-gluco,何首乌苷,EH-201	Others	Others
	Tetrahydroxystilbene-2-O-β-D-glucoside (EH-201) 是一种低分子量的促红细胞生成素诱导剂。
T2888	Pterostilbene 紫檀茋,紫檀芪	Autophagy	Autophagy
	Pterostilbene 是从蓝莓和囊状紫檀中得到的一种芪类天然产物，可抑制 ROS 的生成，能对抗多种自由基，具有抗氧化、抗炎、抗癌、抗糖尿病和抗肥胖等作用。
TN7115	3,5-Dimethoxystilbene 3,5-二甲氧基二苯乙烯,cis-Pinosylvin dimethyl ether	Others	Others
	3,5-Dimethoxystilbene (cis-Pinosylvin dimethyl ether) 是一种从短叶松 Pinus bunksiuna 树皮中分离出来的天然产物。
T2964	2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside 芪多酚,2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside,2,3,5,4'-Tetrahydroxystilbene-2-O-b-D-glucopyranoside,Astragalus polyphenols	Others	Others
	2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside (Astragalus polyphenols) 是分离自蓼属植物物种的根中，对5-HETE、HHT、thromboxane B2的形成具有抑制作用。
T2S2382	3'-Hydroxypterostilbene 3’-羟基紫檀茋,3'-羟基紫檀茋,3'-HPT	Apoptosis; Autophagy	Apoptosis; Autophagy
	3'-Hydroxypterostilbene (3'-HPT) 是天然紫檀芪类似物，通过诱导细胞凋亡和自噬，有效抑制人结肠癌细胞的生长。它抑制 PI3K/Akt/mTOR/p70S6K 和 p38MAPK 途径并激活 ERK1/2，JNK1/2 MAPK 途径。
TN2941	3-Hydroxy-4',5-dimethoxystilbene	Others	Others
	3-Hydroxy-4',5-dimethoxystilbene是一种天然产物，属于百合科龙血树属，其产品编号为 TN2941，CAS号为 58436-29-6。3-Hydroxy-4',5-dimethoxystilbene可用作对照参考。
TN3906	(E)-3-Acetoxy-5-methoxystilbene	Others	Others
	(E)-3-Acetoxy-5-methoxystilbene 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3906，CAS号为 71144-78-0。
TN5724	3,5,3'-Trihydroxystilbene
	3,5,3'-Trihydroxystilbene 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5724，CAS号为 150258-84-7。
TQ0188	Miquelianin 槲皮素-3-O-葡萄糖醛酸苷,Quercetin 3-glucuronide,Quercetin 3-O-glucuronide	stilbene oxidase; Endogenous Metabolite	Metabolism
	Miquelianin (Quercetin 3-glucuronide) 是槲皮素的代谢产物，属于类黄酮化合物。
T6S1597	Mulberroside A 桑皮苷 A,桑皮苷A	TNF; Tyrosinase; Interleukin	Apoptosis; Immunology/Inflammation; Proteases/Proteasome
	Mulberroside A 是桑中的一种主要活性成分，可降低TNF-α、IL-1β和IL-6的表达，抑制 NALP3、caspase-1 和 NF-κB 的激活以及 ERK、JNK 和 p38 的磷酸化。它抑制蘑菇酪氨酸酶，具有抗炎和抗细胞凋亡作用。
T81095	Stenophyllol B
	Stenophyllol B (compound 4) 是一种具有双环及桥联三环骨架的三聚芪类化合物。该化合物最初在龙脑香科植物中被鉴定，随后在Hopea、Neobalanocarpus、Shorea、Stemonoporus以及Vateri等属的多种物种中发现。
T75700	Longistyline A
	Longistyline A (Longistylin A) 是一种天然二苯乙烯，可从木豆中提取。Longistyline A 对耐甲氧西林金黄色葡萄球菌具有抑菌效应，MIC 值为 1.56 μg/mL。Longistyline A 具有神经保护作用，可用于感染和神经系统疾病的研究。

天然产物

trans-Stilbene

Cat.No: TN2282

Synonym: 反式-1,2二苯乙烯,1,2-Diphenylethylene (trans),(E)-Stilbene

Target: Others

trans-Trimethoxyresveratrol

Cat.No: T3330

Synonym: trans-trismethoxy Resveratrol,E-Resveratrol Trimethyl Ether,MR-3,Tri-O-methylresveratrol,白藜芦醇三甲醚,3,4',5-Trimethoxy-trans-stilbene,Trimethoxystilbene

Target: Reactive Oxygen Species

Cat.No: T3755

Target: Others

Tetrahydroxystilbene-2-O-β-D-glucoside

Cat.No: T4956

Synonym: tetrahydroxyl diphenylethylene-2-o-gluco,何首乌苷,EH-201

Target: Others

Cat.No: T2888

Synonym: 紫檀茋,紫檀芪

Target: Autophagy

3,5-Dimethoxystilbene

Cat.No: TN7115

Synonym: 3,5-二甲氧基二苯乙烯,cis-Pinosylvin dimethyl ether

Target: Others

2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside

Cat.No: T2964

Synonym: 芪多酚,2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside,2,3,5,4'-Tetrahydroxystilbene-2-O-b-D-glucopyranoside,Astragalus polyphenols

Target: Others

3'-Hydroxypterostilbene

Cat.No: T2S2382

Synonym: 3’-羟基紫檀茋,3'-羟基紫檀茋,3'-HPT

Target: Apoptosis, Autophagy

3-Hydroxy-4',5-dimethoxystilbene

Cat.No: TN2941

Target: Others

(E)-3-Acetoxy-5-methoxystilbene

Cat.No: TN3906

Target: Others

3,5,3'-Trihydroxystilbene

Cat.No: TN5724

Cat.No: TQ0188

Synonym: 槲皮素-3-O-葡萄糖醛酸苷,Quercetin 3-glucuronide,Quercetin 3-O-glucuronide

Target: stilbene oxidase, Endogenous Metabolite

Cat.No: T6S1597

Synonym: 桑皮苷 A,桑皮苷A

Target: TNF, Tyrosinase, Interleukin

Cat.No: T81095

Cat.No: T75700

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