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Search Results for " st1 "

Targets Recommended: 5-HT Receptor

6

抑制剂 & 化合物

1

TargetMol 试剂盒

13

重组蛋白

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Cat. No.	Product Name	Form	Specificity Of Inhibition
CEPY-0006	Human Cystatin SN/CST1 ELISA Pair Set Human Cystatin SN/CST1 ELISA 抗体对

TargetMol 试剂盒

Human Cystatin SN/CST1 ELISA 抗体对

Cat.No: CEPY-0006

Cat. No.	Product Name	Target	Signaling Pathways
T23396	ST1936 ST 1936 oxalate	5-HT Receptor	GPCR/G Protein; Neuroscience
	ST1936 (ST 1936 oxalate) 是一种具有选择性和高效性的 5-HT6 受体激动剂，抑制人 5-HT6、5-HT7 和 5-HT2B 受体，通过完全激活克隆的人 5-HT6 受体来刺激 cAMP、Ca2+、ERK1/2 和 Fyn 激酶。
T62512	IHMT-MST1-58	Hippo pathway	Stem Cells
	IHMT-MST1-58 是一种 STE20-like protein 1 kinase (MST1) 抑制剂（IC50 ：23 nM），具有高效性、选择性和口服活性。IHMT-MST1-58 可用于研究 1 型或 2 型糖尿病。
T81102	ST1074	Apoptosis	Apoptosis
	ST1074为CerS2/CerS4双重抑制剂，能够诱导细胞凋亡，常用于癌症研究。
T72016	ST101036
	MC activators have recently been described as safe and effective vaccine adjuvants. ST101036 exhibited high degranulation potency in both human and mouse MCs.
T13007	ST1936 oxalate	5-HT Receptor	GPCR/G Protein; Neuroscience
	ST1936 oxalate 是一种 5-HT6 受体的选择性纳摩尔亲和激动剂，对人5-HT6、5-HT7和 5-HT2B 受体的 Ki 值分别为 13、168 和 245 nM。
T39631	Chst15-IN-1 Chst15-IN-1
	Chst15-IN-1 is a powerful, reversible, covalent inhibitor of the Chst15 enzyme. It effectively suppresses the sulfation levels of chondroitin sulfate-E (CS-E) and other closely related sulfotransferases responsible for glycosaminoglycans (GAGs) synthesis. Acting as a selective sulfotransferase inhibitor, Chst15-IN-1 can attenuate the inhibitory actions of chondroitin sulfate proteoglycans (CSPGs), making it a promising candidate for enhancing neuronal repair.

化合物

Cat.No: T23396

Synonym: ST 1936 oxalate

Target: 5-HT Receptor

Cat.No: T62512

Target: Hippo pathway

Cat.No: T81102

Target: Apoptosis

Cat.No: T72016

Cat.No: T13007

Target: 5-HT Receptor

Cat.No: T39631

Synonym: Chst15-IN-1

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04817	Syntenin Protein, Human, Recombinant (His) MDA-9,SYCL,TACIP18,syndecan binding protein (synten...	Human	E. coli
	Syntenin1/SDCBP (syndecan binding protein), also known as melanoma differentiation associated gene-9 (MDA-9), is a PDZ domain-containing molecule, which was initially identified as a key oncogene in melanoma. IL-6 promotes glioma cell proliferation and invasion by inducing SDCBP expression, which is mediated by JAK2/STAT3 signaling. SDCBP might be an important marker for identifying Triple negative breast cancer (TNBC) cases that are suitable for dasatinib therapy.
TMPH-02711	HIST1H2BM Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. HIST1H2BM Protein, Mouse, Recombinant (His) is expressed in E...
TMPY-01332	HIST1H3A Protein, Human, Mouse, Recombinant Histone H3.1,histone clust	Human,Mouse	E. coli
	Histone H3.1, also known as HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, is a member of the histone H3 family which is a core component of nucleosome. It is expressed during the S phase, then expression strongly decreases as cell division slows down during the process of differentiation. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machinery which requires DNA as a template. Histones thereby pla...
TMPY-04398	MST1 Protein, Human, Recombinant (His) serine/threonine kinase 4,KRS2,MST1,TIIAC,...	Human	Baculovirus Insect Cells
	Dysregulation of MST1/STK4, a key kinase component of the Hippo-YAP pathway, is linked to the etiology of many cancers with poor prognosis. STK4/Hippo pathway may have important therapeutic implications for cancer. The tumor suppressor serine/threonine-protein kinase 4 (STK4) differentially regulates TLR3/4/9-mediated inflammatory responses in macrophages and thereby is protective against chronic inflammation-associated Hepatocellular carcinoma (HCC). STK4 has potential as a diagnostic biomarker...
TMPH-01007	NDST1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	NDST1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 73.5 kDa and the accession number is P52848.
TMPH-01477	HIST1H1D Protein, Human, Recombinant (His & MBP)	Human	E. coli
	Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation. HIST1H1D Protein, Human, Recombinant (His & MBP) is expressed in E. coli expression system with N-MBP and C-6xHis tag. The predicted molecula...
TMPH-02710	HIST1H2BA Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	HIST1H2BA Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli.
TMPH-01478	HIST1H2AG Protein, Human, Recombinant (His)	Human	E. coli
	HIST1H2AG Protein, Human, Recombinant (His) is expressed in E. coli.
TMPK-00516	BST1 Protein, Cynomolgus, Recombinant (His) Bp-3,CD157,Bst1,BST-...	Cynomolgus	HEK293 Cells
	BST1 overexpression conferred resistance to sphingosine in yeast. BST1 deletion produced sensitivity to exogenous D-erythro-sphingosine and phytosphingosine and intracellular accumulation of sphingosine 1-phosphate upon exposure to exogenous sphingosine. sphingoid base metabolism is similar in all eukaryotes and suggests that yeast genetics may be useful in the isolation and identification of other genes involved in sphingolipid signaling and metabolism.
TMPY-01818	TPST1 Protein, Human, Recombinant (His) tyrosylprotein sulfotransferase 1,TANGO13A	Human	HEK293 Cells
	Protein-tyrosine sulfotransferase 1, also known as Tyrosylprotein sulfotransferase 1 and TPST1, is a single-pass type II membrane protein that belongs to the protein sulfotransferase family. Tyrosine O-sulfation is a common posttranslational modification of proteins in all multicellular organisms. This reaction is mediated by a Golgi enzyme activity called tyrosylprotein sulfotransferase (TPST) that catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate to tyrosine residues...
TMPY-00290	HS3ST1 Protein, Human, Recombinant (His) 3OST1,3OST,heparan sulfate (gluco...	Human	Baculovirus Insect Cells
	HS3ST1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 36 kDa and the accession number is AAH57803.1.
TMPY-03959	CHST11 Protein, Human, Recombinant (His) carbohydrate (chondroitin 4) sulfotransferase 1...	Human	Baculovirus Insect Cells
	CHST11, also known as C4ST-1, belongs to the sulfotransferase 2 family. CHST11 localizes to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving CHST11 gene and IgH, t(12;14)(q23;q32), has been reported in a patient with ...
TMPY-01707	CHST15 Protein, Human, Recombinant (His) BRAG,carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulf...	Human	HEK293 Cells
	Carbohydrate sulfotransferase 15, also known as N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase, GalNAc4S-6ST, B-cell RAG-associated gene protein, CHST15 and BRAG, is a single-pass type II membrane protein which belongs to thesulfotransferase 1 family. CHST15 / BRAG is expressed in B-cell-enriched tissues but not in fetal or adult thymus. It is expressed in fetal and adult spleen, lymph node, tonsil, bone marrow and peripheral leukocytes. It is not expressed in T-cells. In pro-B, pre...

重组蛋白

Syntenin Protein, Human, Recombinant (His)

Cat.No: TMPY-04817

Species: Human

Expression System: E. coli

HIST1H2BM Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02711

Species: Mouse

Expression System: E. coli

HIST1H3A Protein, Human, Mouse, Recombinant

Cat.No: TMPY-01332

Species: Human,Mouse

Expression System: E. coli

MST1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04398

Species: Human

Expression System: Baculovirus Insect Cells

NDST1 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01007

Species: Human

Expression System: E. coli

HIST1H1D Protein, Human, Recombinant (His & MBP)

Cat.No: TMPH-01477

Species: Human

Expression System: E. coli

HIST1H2BA Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02710

Species: Mouse

Expression System: E. coli

HIST1H2AG Protein, Human, Recombinant (His)

Cat.No: TMPH-01478

Species: Human

Expression System: E. coli

BST1 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00516

Species: Cynomolgus

Expression System: HEK293 Cells

TPST1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01818

Species: Human

Expression System: HEK293 Cells

HS3ST1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00290

Species: Human

Expression System: Baculovirus Insect Cells

CHST11 Protein, Human, Recombinant (His)

Cat.No: TMPY-03959

Species: Human

Expression System: Baculovirus Insect Cells

CHST15 Protein, Human, Recombinant (His)

Cat.No: TMPY-01707

Species: Human

Expression System: HEK293 Cells

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