首页工具

登录

搜索结果

Search Results for " slf "

Targets Recommended: Others

10

抑制剂 & 化合物

6

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T13888	SLF	Others	Others
	SLF is a synthetic ligand for FK506-binding protein (FKBP)( with an affinity of 3.1 μM for FKBP51 and an IC50 of 0.22 μM for FKBP12). SLF can be used in the synthesis of PROTAC.
T18061	KB02-SLF	Others	Others
	KB02-SLF is a PROTAC-based nuclear FKBP12 degrader, known as a molecular glue. It facilitates the degradation of nuclear FKBP12 by covalently modifying DCAF16, an E3 ligase. Moreover, KB02-SLF enhances the longevity of protein degradation in biological systems. The compound SLF acts as a linker, binding to the ubiquitin E3 ligase ligand KB02, resulting in the formation of KB02-SLF[1].
T13914	SLF-amido-C2-COOH PROTAC FKBP12-binding moiety 1	Others	Others
	SLF-amido-C2-COOH is a synthetic ligand for FKBP (SLF), and can be used in the synthesis of PROTACs.
T73817	SLF TFA
	SLF TFA 是 FK506 结合蛋白 (FKBP) 的合成配体，对FKBP51的亲和力为 3.1 μM，对FKBP12的IC50为 2.6 μM，可用于合成PROTAC 分子。
T61112	SLF1081851	LPL Receptor	GPCR/G Protein
	SLF1081851 是一种 Spns2 抑制剂，抑制 S1P 释放 (IC50=1.93 μM)。SLF1081851 在发育和免疫系统中起关键作用。
T62851	SLF1081851 TFA
	SLF1081851 (TFA) 是一种 Spns2 抑制剂，抑制 S1P 释放的 IC50 值为 1.93 μM。SLF1081851 (TFA) 在发育和免疫系统中发挥着关键作用。
T74026	AUTAC2
	AUTAC2 是一种 FKBP12靶向自噬介导降解体 (AUTAC)。AUTAC2 包含一个 FBnG 和 SLF 部分，其中 SLF 与 FKBP12 非共价结合。
T39923	KB02-COOH KB02-COOH
	KB02-COOH is a synthetic fragment derived from ubiquitin E3 ligase ligand KB02, which possesses potential utility in the synthesis of PROTAC compounds. Notably, KB02-COOH can be employed in the generation of PROTAC constructs like KB02-JQ1 and KB02-SLF.
T18597	dFKBP-1	Others	Others
	dFKBP-1 is a potent and PROTAC-based FKBP12 degrader. dFKBP-1 incorporates the ligand SLF of FKBP12, the Thalidomide based cereblon ligand and a linker[1].
T80928	TSPO ligand-3	AUTACs	PROTAC
	TSPO ligand-3为AUTAC2的配体，其中AUTAC2包含p-氟苄基鸟嘌呤(FBnG)及FKBP合成配体(SLF)两部分，能在HeLa细胞中显著沉默FKBP12蛋白。

化合物

Cat.No: T13888

Target: Others

Cat.No: T18061

Target: Others

SLF-amido-C2-COOH

Cat.No: T13914

Synonym: PROTAC FKBP12-binding moiety 1

Target: Others

Cat.No: T73817

Cat.No: T61112

Target: LPL Receptor

SLF1081851 TFA

Cat.No: T62851

Cat.No: T74026

Cat.No: T39923

Synonym: KB02-COOH

Cat.No: T18597

Target: Others

Cat.No: T80928

Target: AUTACs

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02105	SCF Protein, Mouse, Recombinant (His) Gb,Kitlg,SF,Clo,Mgf,SLF,Sl,KIT ligand,SCF,Con	Mouse	Baculovirus Insect Cells
	SCF Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 19.7 kDa and the accession number is P20826-1.
TMPY-05135	SCF Protein, Mouse, Recombinant (His), Biotinylated Con,SLF,SF,Mgf,Gb,Clo,KIT ligand,Sl,Kitlg,SCF	Mouse	Baculovirus Insect Cells
	SCF Protein, Mouse, Recombinant (His), Biotinylated is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 19.7 kDa and the accession number is P20826-1.
TMPJ-00895	SCF Protein, Rat, Recombinant (HEK293, His) steel factor,Mast cell growth factor,SLF,MGFSHEP7,S...	Rat	HEK293 Cells
	SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. In phase I/II...
TMPH-02063	SLFN12 Protein, Human, Recombinant (His)	Human	E. coli
	SLFN12 Protein, Human, Recombinant (His) is expressed in in vitro E. coli expression system.
TMPH-02062	SLFN11 Protein, Human, Recombinant (His)	Human	E. coli
	SLFN11 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 69.6 kDa and the accession number is Q7Z7L1.
TMPK-01441	HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Monomer Protein, Human, MHC (His & Avi) OIP-4,PRAME,MAPE,OIP4	Human	HEK293 Cells
	PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumors is limited.

重组蛋白

SCF Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02105

Species: Mouse

Expression System: Baculovirus Insect Cells

SCF Protein, Mouse, Recombinant (His), Biotinylated

Cat.No: TMPY-05135

Species: Mouse

Expression System: Baculovirus Insect Cells

SCF Protein, Rat, Recombinant (HEK293, His)

Cat.No: TMPJ-00895

Species: Rat

Expression System: HEK293 Cells

SLFN12 Protein, Human, Recombinant (His)

Cat.No: TMPH-02063

Species: Human

Expression System: E. coli

SLFN11 Protein, Human, Recombinant (His)

Cat.No: TMPH-02062

Species: Human

Expression System: E. coli

HLA-A*02:01&B2M&PRAME (ALYVDSLFFL) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01441

Species: Human

Expression System: HEK293 Cells

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼