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Search Results for " sapk "

Targets Recommended: p38 MAPK

1

抑制剂 & 化合物

1

天然产物

2

化合物库

11

重组蛋白

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Cat. No.	Product Name
L1610	FDA 上市激酶抑制剂库		263 compounds
	263种靶向激酶的上市药物集合，用于特定靶向激酶，可用于高通量筛选和高内涵筛选；
L1600	激酶抑制剂库		2720 compounds
	2720 种激酶抑制剂/调节剂的独特集合，用于特定靶向激酶，可用于高通量筛选和高内涵筛选；

化合物库

FDA 上市激酶抑制剂库

Cat.No: L1610

Compounds: 263

激酶抑制剂库

Cat.No: L1600

Compounds: 2720

Cat. No.	Product Name	Target	Signaling Pathways
T27627	Iroxanadine BRX005,BRX-235,BRX-005,BRX235,BRX 005,BRX 235	p38 MAPK	MAPK
	Iroxanadine (BRX-005) 是一种新型小分子MAPK p38 抑制剂，诱导p38 SAPK 的磷酸化，在用去氧肾上腺素预先收缩的豚鼠肺动脉制剂中诱导浓度依赖性松弛，可用于治疗动脉粥样硬化、糖尿病血管病，微血管心绞痛和外周动脉疾病等血管疾病。

化合物

Cat.No: T27627

Synonym: BRX005,BRX-235,BRX-005,BRX235,BRX 005,BRX 235

Target: p38 MAPK

Cat. No.	Product Name	Target	Signaling Pathways
T3864	Erianin	BCL; Antibacterial	Apoptosis; Microbiology/Virology
	Erianin 能抑制吲哚胺-2,3-双加氧酶诱导的肿瘤血管生成，可用作退烧药和止疼剂。

天然产物

Cat.No: T3864

Target: BCL, Antibacterial

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04430	p38 gamma/MAPK12 Protein, Human, Recombinant mitogen-activated protein kinase 12,SAPK-3,P38 γ/MA...	Human	Baculovirus Insect Cells
	p38 gamma/MAPK12 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 42.1 kDa and the accession number is P53778.
TMPY-04429	p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST) ERK3,SAPK3,PRKM12,ERK6,P38γ,P38GAMMA,mitogen-activa...	Human	Baculovirus Insect Cells
	p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69.8 kDa and the accession number is P53778.
TMPY-04550	JNK2 Protein, Human, Recombinant (His) JNK2α,SAPK1a,PRKM9,JNK2β,JNK2,SAPK,JNK2BET...	Human	Baculovirus Insect Cells
	Mitogen-activated protein kinase 9 (MAPK9), also well known as c-Jun N-terminal kinase (JNK2), is a member of the MAP kinase subfamily belonging to the protein kinase superfamily. MAPK9 responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating some transcription factors, such as c-Jun and ATF2. The crystal structure of human JNK2 complexed with an indazole inhibitor by applying a high-throughput protein engineering and surface-site mutagenesis approach. A n...
TMPY-04551	p38 delta/MAPK13 Protein, Human, Recombinant (GST) MAPK13,p38δ,PRKM13,MAPK-13,mitogen-activated protein kinase ...	Human	Baculovirus Insect Cells
	p38 delta/MAPK13 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 68.4 kDa and the accession number is O15264.
TMPY-04531	p38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro P38 δ/MAPK13,MAPK13,PRKM13,MAPK-13,p38δ,p38delta,mitogen-act...	Human	Baculovirus Insect Cells
	p38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 68.4 kDa and the accession number is O15264.
TMPY-04554	JNK1 Protein, Human, Recombinant (GST) PRKM8,JNK,JNK-46,JNK21B1/2,JNK1A2,mitogen-activated protein ...	Human	Baculovirus Insect Cells
	Mitogen-activated protein kinase 8 (MAPK8), also known as JNK1, is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. The protein kinases JNK1 has been found to serve as critical molecular links between obesity, metabolic inflammation, and disorders of glucose homeostasis. It is critically involved in ...
TMPY-04572	MKK4 Protein, Mouse, Recombinant (His & GST) MKK4,MEK4,PRKMK4,Sek1,JNKK1,Serk1,mitogen-activated protein ...	Mouse	Baculovirus Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is a protein that belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase subfamily. MAP2K4 / JNKK1 is a protein kinase that is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. MAP2K4 / ...
TMPJ-01353	MBIPP Protein, Human, Recombinant (His) MAPK Upstream Kinase-Binding Inhibitory Protein,MUK-Binding ...	Human	E. coli
	MAP3K12-binding inhibitory protein 1 (MBIP) is a 39kD protein high expression in the heart and lung. It is a component of the ADA2A-containing complex (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4, and composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. In the complex, it probably interacts directly with KAT2A, CSRP2BP and WDR5. It’s function to inhibit the MAP3K12 activity to induce the activation of the JNK/SAPK pathwa...
TMPY-04399	TAOK3 Protein, Human, Recombinant (aa 1-411, His & GST) DPK,MAP3K18,TAO kinase 3,JIK	Human	Baculovirus Insect Cells
	Serine/threonine-protein kinase TAO3, also known as cutaneous T-cell lymphoma-associated antigen HD-CL-9, CTCL-associated antigen HD-CL-9, Dendritic cell-derived protein kinase, JNK / SAPK-inhibitory kinase, Jun kinase-inhibitory kinase, Kinase from chicken homolog A, Thousand and one amino acid protein 3, JIK, TAOK3 and MAP3K18, is cytoplasm and peripheral membrane protein which belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and STE2 subfamily. Protein kinases are ...
TMPY-02150	GADD45A Protein, Human, Recombinant (His & GST) GADD45,growth arrest and DNA-damage-inducible, alpha,growth ...	Human	Baculovirus Insect Cells
	GADD45A is a member of the GADD45 Family, and has been found to associate with several cytoplasmic and nuclear factors and has been implicated in several cellular functions, including MAPK signaling, cell cycle regulation, DNA repair and genomic stability, apoptosis, and immune responses. The GADD45 Family of genes is rapidly induced by different stressors, including differentiation-inducing cytokines, and there is a large body of evidence that their cognate proteins are key players in cellular ...
TMPY-04391	Lyn Protein, Human, Recombinant (GST) JTK8,LYN proto-oncogene, Src family tyrosine kinase,p56Lyn,p...	Human	Baculovirus Insect Cells
	Tyrosine-protein kinase Lyn is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells, in neural tissues liver, and adipose tissue. Tyrosine-protein kinase Lyn has many functions. Lyn kinase may downregulate the expression of stem cell growth factor receptor (KIT). Lyn kinase Acts as an effector of EpoR (erythropoietin receptor) in controlling KIT expression and may play a central role in erythroid differentiation during the switch between prolif...

重组蛋白

p38 gamma/MAPK12 Protein, Human, Recombinant

Cat.No: TMPY-04430

Species: Human

Expression System: Baculovirus Insect Cells

p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04429

Species: Human

Expression System: Baculovirus Insect Cells

JNK2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04550

Species: Human

Expression System: Baculovirus Insect Cells

p38 delta/MAPK13 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04551

Species: Human

Expression System: Baculovirus Insect Cells

p38 delta/MAPK13 Protein, Human, Recombinant (GST), Activated in vitro

Cat.No: TMPY-04531

Species: Human

Expression System: Baculovirus Insect Cells

JNK1 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04554

Species: Human

Expression System: Baculovirus Insect Cells

MKK4 Protein, Mouse, Recombinant (His & GST)

Cat.No: TMPY-04572

Species: Mouse

Expression System: Baculovirus Insect Cells

MBIPP Protein, Human, Recombinant (His)

Cat.No: TMPJ-01353

Species: Human

Expression System: E. coli

TAOK3 Protein, Human, Recombinant (aa 1-411, His & GST)

Cat.No: TMPY-04399

Species: Human

Expression System: Baculovirus Insect Cells

GADD45A Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02150

Species: Human

Expression System: Baculovirus Insect Cells

Lyn Protein, Human, Recombinant (GST)

Cat.No: TMPY-04391

Species: Human

Expression System: Baculovirus Insect Cells

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