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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T24700 R243

R 243,R-243

CCR Immunology/Inflammation; Microbiology/Virology
R243 是选择性的CCR8拮抗剂,可抑制CCL1/CCR8的相互作用,以及CCR8信号传导和趋化性,具有抗伤害感受和抗炎作用。
T0351 Risperidone

Risperidal,R 64 766,利培酮

Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; P-gp GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
Risperidone (R 64 766) 是5-HT2受体阻断剂、P-糖蛋白抑制剂和多巴胺 D2受体的拮抗剂,对 5-HT2A 和多巴胺 D2受体的 Ki 值分别为 4.8 和 5.9 nM。

化合物

R243
Cat.No: T24700
Synonym: R 243,R-243
Target: CCR
Risperidone
Cat.No: T0351
Synonym: Risperidal,R 64 766,利培酮
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, P-gp
Cat. No. Product Name Target Signaling Pathways
T35624 Ajoene

Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs = 5-160 &#181g/ml) and Gram-negative bacteria (MICs = 136-200 &#181g/ml), as well as yeasts (MICs = 10-20 &#181g/ml).1Ajoene is cytotoxic to mouse melanoma cells (IC50= 18 &#181M), as well as human colon, lung, mammary, and pancreatic cancer cells (IC50s = 7-41 &#181M).2It reduces...

天然产物

Ajoene
Cat.No: T35624
Synonym:
Target:
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