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抑制剂 & 化合物

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T28047	Mitoquinone-cyclodextrin MitoQ10,Mitoubiquinone mesylate,MitoQ-10,MitoQ,Mito Q10,Mitoquinone mesylate-cyclodextrin
	Mitoquinone-cyclodextrin is a 1:1 molar ratio complex of Mitoquinone mesylate with cyclodextrin. Mitoquinone mesylate is a mitochondria-targeted antioxidant designed to accumulate within mitochondria in vivo in order to protect against oxidative damage. M
T0412	Idebenone 艾地苯醌,CV-2619	Apoptosis; Antioxidant; Mitochondrial Metabolism	Apoptosis; Metabolism; oxidation-reduction
	Idebenone (CV-2619) 是一种线粒体保护剂，具有神经保护功效，可用于研究阿尔茨海默病、亨廷顿舞蹈病，可透过血脑屏障，诱导细胞凋亡。
T16925	SQ109 NSC 722041	Others; Parasite	Microbiology/Virology; Others
	SQ109 (NSC-722041) 是一种有效的锥鞭毛体形式的寄生虫抑制剂 (IC50 = 50 nM)。 SQ109 是一种抗结核药物，靶向 MmpL3。
T63200	NTQ1062
	NTQ1062 (compound 22b) 是口服具有活力的、有效的Akt 抑制剂，能够作用于 Akt1 (IC50: 0.4 nM)、Akt2 (IC50: 6.3 nM) 和 Akt3 (IC50: 0.1 nM)。NTQ1062 对多种癌细胞表现出抗增殖作用，能够将细胞周期阻滞在 G0/G1 期，诱导细胞凋亡 (apoptosis)。NTQ1062 在 LNCap 异种移植瘤小鼠模型中显示出显著的的抗肿瘤效果。
T30997	Coenzyme Q12 Ubiquinone Q-12,Ubiquinone 12,trans-Coenzyme Q12,Coenzyme Q-12,J93.222A
	Coenzyme Q10 is a vitamin-like substance found throughout the body, especially in the heart, liver, kidneys, and pancreas.
T13243	Ubiquinol Ubiquinol-10,CoQH2-10	Others	Others
	Ubiquinol is a reduced form of coenzyme Q10 (CoQ10) and is a potent antioxidant that has the capacity to protect Vitamin E.
T36114	Coenzyme Q2
	Coenzyme Q10 is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. In its reduced form, it acts as an antioxidant. Coenzyme Q2 is a precursor of coenzyme Q10 that has 2, rather than 10, isoprenoid units on the ubiquinone base. It can act as an electron acceptor for bacterial Complex I. In mammalian cells, exogenous coenzyme Q2 prevents the production of reactive oxygen species associated with Complex I activity. For...
T35881	Resolvin E2
	Resolvin E2 (RvE2) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.1It is produced from eicosapentaenoic acidviaan 18-HEPE intermediate, which is formed by aspirin-acetylated COX-2-mediated oxidation of EPA, by 5-lipoxygenase (5-LO) in human polymorphonuclear (PMN) neutrophils.2,3RvE2 (20 ng/animal) inhibits increases in inflammatory exudate neutrophil infiltration in a mouse model of peritonitis induced by zymosan A .3Hepatic RvE2 levels are increased in m...

化合物

Mitoquinone-cyclodextrin

Cat.No: T28047

Synonym: MitoQ10,Mitoubiquinone mesylate,MitoQ-10,MitoQ,Mito Q10,Mitoquinone mesylate-cyclodextrin

Target:

Idebenone

Cat.No: T0412

Synonym: 艾地苯醌,CV-2619

Target: Apoptosis, Antioxidant, Mitochondrial Metabolism

SQ109

Cat.No: T16925

Synonym: NSC 722041

Target: Others, Parasite

Synonym: Ubiquinone Q-12,Ubiquinone 12,trans-Coenzyme Q12,Coenzyme Q-12,J93.222A

Target:

Ubiquinol

Cat.No: T13243

Synonym: Ubiquinol-10,CoQH2-10

Cat. No.	Product Name	Target	Signaling Pathways
T2796	Coenzyme Q10 Ubiquinone-10,辅酶Q10,CoQ10	Ferroptosis; Reactive Oxygen Species; Endogenous Metabolite	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB
	Coenzyme Q10 (CoQ10)是来自藤仓赤霉菌的一种天然产物，在线粒体呼吸链中充当电子载体。
T3236	Solanesol Betulanonaprenol,茄尼醇,Nonaisoprenol	Others; Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology; Others
	Solanesol (Betulanonaprenol) 是主要存在于茄科植物中的脂肪族萜烯醇，有抗炎、神经保护和抗菌活性。

天然产物

Coenzyme Q10

Cat.No: T2796

Synonym: Ubiquinone-10,辅酶Q10,CoQ10

Target: Ferroptosis, Reactive Oxygen Species, Endogenous Metabolite

Solanesol

Cat.No: T3236

Synonym: Betulanonaprenol,茄尼醇,Nonaisoprenol

Target: Others, Endogenous Metabolite, Antibacterial

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