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Cat. No.	Product Name	Target	Signaling Pathways
T2384	Pomalidomide CC-4047,泊马度胺	Apoptosis; TNF; Ligand for E3 Ligase; Molecular Glues	Apoptosis; PROTAC
	Pomalidomide (CC-4047) 是一种抗血管生成剂和免疫调节剂，以分子胶的方式作用。它与 E3 连接酶 cereblon 相互作用，诱导必需的 Ikaros 转录因子的降解。
T40025	Pomalidomide-PEG2-CO2H Pomalidomide 4'-PEG2-acid,Pomalidomide-PEG2-C2-acid	E3 Ligase Ligand-Linker Conjugate	PROTAC
	Pomalidomide-PEG2-CO2H 是一种合成的 E3 连接酶配体-接头偶联物，包含基于 Pomalidomide 的 cereblon 配体和 2 单元 PEG 接头。
T40024	Pomalidomide-PEG1-CO2H Pomalidomide-PEG1-C2-COOH	E3 Ligase Ligand-Linker Conjugate	PROTAC
	Pomalidomide-PEG1-CO2H 是一种合成的 E3 连接酶配体-接头偶联物，包含基于 Pomalidomide 的 cereblon 配体和 2 单元 PEG 接头。
T40007	Pomalidomide-C5-COOH	Others	Others
	Pomalidomide-C5-COOH 是一种合成的 E3 连接酶配体-接头偶联物，它结合了 PROTAC 技术中使用的基于 Pomalidomide 的 CRBN 配体和接头。
T40009	Pomalidomide-C4-COOH	Others	Others
	Pomalidomide-C4-COOH 是一种合成的 E3 连接酶配体-接头偶联物，它结合了 PROTAC 技术中使用的基于 Pomalidomide 的 CRBN 配体和接头。
T40001	Pomalidomide-C6-COOH	Others	Others
	Pomalidomide-C6-COOH 是一种合成的 E3 连接酶配体-接头偶联物，它结合了 PROTAC 技术中使用的基于 Pomalidomide 的 CRBN 配体和接头。
T40014	Pomalidomide-C4-OH	Others	Others
	Pomalidomide-C4-OH 是一种合成的 E3 连接酶配体-接头偶联物，它结合了 PROTAC 技术中使用的基于 Pomalidomide 的 CRBN 配体和接头。
T40005	Pomalidomide-C2-COOH	Others	Others
	Pomalidomide-C2-COOH 是一种合成的 E3 连接酶配体-接头偶联物，它结合了 PROTAC 技术中使用的基于 Pomalidomide 的 CRBN 配体和接头。
T40020	Pomalidomide-C2-acid	Others	Others
	Pomalidomide-C2-acid 是 PROTAC 的组成部分。
T40000	Pomalidomide-C3-I	Others	Others
	Pomalidomide-C3-I 是一种合成的 E3 连接酶配体-接头偶联物，它结合了 PROTAC 技术中使用的基于 Pomalidomide 的 CRBN 配体和接头。
T40004	Pomalidomide-C7-NH2 hydrochloride	Others	Others
	Pomalidomide-C7-NH2 hydrochloride 是一种合成的 E3 连接酶配体-接头偶联物，它结合了 PROTAC 技术中使用的基于 Pomalidomide 的 CRBN 配体和接头。
T40008	Pomalidomide-C6-I TFA	Others	Others
	Pomalidomide-C6-I TFA 是一种合成的 E3 连接酶配体-接头偶联物，它结合了 PROTAC 技术中使用的基于 Pomalidomide 的 CRBN 配体和接头。
T40015	Pomalidomide-PEG2-NH2 hydrochloride	Others	Others
	Pomalidomide-PEG2-NH2 hydrochloride 是一种合成的 E3 连接酶配体-接头偶联物，它结合了 PROTAC 技术中使用的基于 Pomalidomide 的 CRBN 配体和接头。
T40023	Pomalidomide-PEG3-CO2H Thalidomide-NH-PEG3-propionic acid	E3 Ligase Ligand-Linker Conjugate	PROTAC
	Pomalidomide-PEG3-CO2H (Thalidomide-NH-PEG3-propionic acid) 是一种由 E3 连接酶配体和连接体组成的偶联物，结合了基于 Thalidomide 的 Cereblon 配体和 3 个单元 PEG Linker。
T9387	Pomalidomide 4'-PEG2-azide	E3 Ligase Ligand-Linker Conjugate	PROTAC
	Pomalidomide 4'-PEG2-azide 是由E3 连接酶配体和linker 组成的偶联物，包括基于 Pomalidomide 的 cereblon 配体和linker。
T40006	Pomalidomide-CH2CONH-C2-COOH	Others	Others
	Pomalidomide-CH2CONH-C2-COOH 是一种合成的 E3 连接酶配体-接头偶联物，它结合了 PROTAC 技术中使用的基于 Pomalidomide 的 CRBN 配体和接头。
T40002	Pomalidomide-C3-NH2 hydrochloride	Others; E3 Ligase Ligand-Linker Conjugate	Others; PROTAC
	Pomalidomide-C3-NH2 hydrochloride 包含基于 Pomalidomide 的 cereblon 配体和 1 个 linker，是合成的 E3 连接酶配体-linker 偶联物，可用于 PROTAC 的合成。
T7761	Pomalidomide-C2-NH2 hydrochloride	E3 Ligase Ligand-Linker Conjugate; Ligand for E3 Ligase	PROTAC
	Pomalidomide-C2-NH2 hydrochloride 包含基于 Pomalidomide 的 cereblon 配体和 1 个 linker，是合成的 E3 连接酶配体-linker 偶联物。
T40032	Pomalidomide-PEG4-C2-NH2 hydrochloride	PROTAC Linker	PROTAC
	Pomalidomide-PEG4-C2-NH2 hydrochloride 是 E3 连接酶配体和 linker 组成的偶联物，包含基于 Pomalidomide 的 cereblon 配体和 4 个单元 PEG 的 linker，可用于 PROTAC 分子的合成。
T17325	Pomalidomide-PEG4-C-COOH Cereblon Ligand -Linker Conjugates 1,E3 Ligase Ligand-Linker Conjugates 1	Others; E3 Ligase Ligand-Linker Conjugate	Others; PROTAC
	Pomalidomide-PEG4-C-COOH (E3 Ligase Ligand-Linker Conjugates 1) 包含基于 Pomalidomide 的 cereblon 配体和 4 个单元 PEG linker，是一种合成的 E3 连接酶配体-linker 偶联物。
T9383	Pomalidomide-PEG2-OH 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-(2-hydroxyethoxy)ethyl]amino]-	PROTACs	PROTAC
	Pomalidomide-PEG2-OH 能够合成用于靶向蛋白质降解和 PROTAC（蛋白水解靶向嵌合体）技术的分子。
T9384	Pomalidomide-PEG3-OH 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]amino]-	PROTACs	PROTAC
	Pomalidomide-PEG3-OH 能够合成用于靶向蛋白质降解和 PROTAC（蛋白水解靶向嵌合体）技术的分子。
T17916	Pomalidomide-PEG4-C2-NH2 Cereblon Ligand-Linker Conjugates 8,E3 Ligase Ligand-Linker Conjugates 22	Others; Ligand for E3 Ligase	Others; PROTAC
	Pomalidomide-PEG4-C2-NH2 (E3 Ligase Ligand-Linker Conjugates 22) 是一种合成的 E3 连接酶配体- linker 偶联物，用于 PROTAC 技术中。
T7756	Pomalidomide-PEG4-Ph-NH2	Ligand for E3 Ligase	PROTAC
	Pomalidomide-PEG4-Ph-NH2 是一种合成的 E3 连接酶配体- linker 偶联物，结合了基于 Pomalidomide 的 cereblon 配体和 4 单元 PEG linker。
T39804	Pomalidomide-PEG3-azide Pomalidomide-PEG3-azide
	Pomalidomide-PEG3-azide is a chemically synthesized conjugate comprised of a cereblon ligand based on Pomalidomide, an E3 ligase ligand-linker, and a 3-unit PEG linker. This conjugate is specifically designed for use in PROTAC technology.
T41163	ZNL 02-096 Pomalidomide-C3-adavosertib	Apoptosis; Wee1	Apoptosis; Cell Cycle/Checkpoint
	ZNL 02-096 (Pomalidomide-C3-adavosertib) 是一种快速和选择性的 Wee1 降解剂 (IC50=3.58 nM)。ZNL 02-096 可在亚摩尔浓度下选择性降解 Wee1，而不损伤 AZD 1775 的二级靶点 PLK1。在体外 MOLT-4 细胞中，ZNL 02-096 可诱导 Wee1 降解、DNA 损伤积累、细胞周期停滞在 G2/M 期和细胞凋亡。ZNL 02-096 在 300 种癌症细胞系中显示出抗增殖作用。
T39803	Pomalidomide-PEG2-azide Pomalidomide-PEG2-azide
	Pomalidomide-PEG2-azide is a synthetic conjugate consisting of a cereblon ligand derived from Pomalidomide and a 2-unit PEG linker, designed for use in PROTAC technology as a ligand-linker conjugate of E3 ligase.
T39701	Pomalidomide-C7-COOH Pomalidomide-C7-COOH
	Pomalidomide-C7-COOH is a chemically synthesized E3 ligase cereblon ligand-linker conjugate, utilized as an intermediate compound for the synthesis of PROTAC BCL-XL degraders.
T39381	Pomalidomide-C4-NH2 Pomalidomide-C4-NH2
	Pomalidomide-C4-NH2 is a chemically synthesized conjugate, consisting of a ligand for E3 ligase (cereblon) derived from Pomalidomide and a linker employed in PROTAC technology.
T39032	Pomalidomide-5-O-CH3 Pomalidomide-5-O-CH3
	Pomalidomide-5-O-CH3, a derivative of Pomalidomide, serves as a specific ligand for cereblon (CRBN) protein recruitment. It can be linked to the protein ligand to create a PROTAC.
T40085	Pomalidomide-amino-PEG5-NH2 hydrochloride Pomalidomide-amino-PEG5-NH2 hydrochloride
	Pomalidomide-amino-PEG5-NH2 hydrochloride is a chemical compound that has been synthesized as an E3 ligase ligand-linker conjugate. This compound combines a Pomalidomide-based cereblon ligand with a linker commonly used in PROTAC technology.
T39636	Pomalidomide-C4-NH2 hydrochloride Pomalidomide-C4-NH2 hydrochloride
	Pomalidomide-C4-NH2 hydrochloride is a synthesized conjugate comprising an E3 ligase ligand-linker. This compound incorporates the cereblon ligand derived from Pomalidomide and a linker that is commonly employed in PROTAC technology.
T39806	Pomalidomide 4'-PEG3-azide Pomalidomide 4'-PEG3-azide
	Pomalidomide 4'-PEG3-azide is a chemically synthesized conjugate consisting of an E3 ligase ligand-linker conjugate that incorporates the cereblon ligand derived from Pomalidomide, along with a linker. This compound, Pomalidomide 4'-PEG3-azide, is utilized in the synthesis of iRucaparib-TP3 (Compound 3). iRucaparib-TP3, developed through the PROTAC strategy, is an effective degrader of PARP1, derived from Rucaparib.
T39637	Pomalidomide-amido-C3-COOH Pomalidomide-amido-C3-COOH
	Pomalidomide-amido-C3-COOH is a conjugate compound synthesized as an E3 ligase ligand-linker. It combines a cereblon ligand derived from Pomalidomide with a linker, both of which are used in PROTAC technology.
T36263	Pomalidomide 4'-alkylC8-acid Pomalidomide 4'-alkylC8-acid
	Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with terminal acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T39033	Pomalidomide-6-O-CH3 Pomalidomide-6-O-CH3
	Pomalidomide-6-O-CH3 is a Pomalidomide-derived ligand for cereblon (CRBN), which serves as a linkage agent to recruit the CRBN protein. This ligand, when connected to a protein via a linker, enables the formation of PROTAC.
T40084	Pomalidomide-amino-PEG5-NH2 Pomalidomide-amino-PEG5-NH2
	Pomalidomide-amino-PEG5-NH2 is a synthesized conjugate combining the Pomalidomide-based cereblon ligand and a linker utilized in PROTAC technology. It acts as an E3 ligase ligand-linker conjugate.
T39866	Pomalidomide-amino-PEG4-NH2 Pomalidomide-amino-PEG4-NH2
	Pomalidomide-amino-PEG4-NH2 is a conjugate compound that combines the Pomalidomide-based cereblon ligand and a linker, effectively functioning as a synthesized E3 ligase ligand-linker conjugate utilized in PROTAC technology.
T39952	Pomalidomide-amino-PEG3-NH2 Pomalidomide-amino-PEG3-NH2
	Pomalidomide-amino-PEG3-NH2 is a compound obtained through synthesis, consisting of a conjugation between the E3 ligase ligand linker and Pomalidomide, a cereblon ligand. This compound is specifically designed for application in PROTAC technology, incorporating a linker that enables effective binding with the targeted proteins.
T39875	Pomalidomide-PEG6-NH2 hydrochloride Pomalidomide-PEG6-NH2 hydrochloride
	Pomalidomide-PEG6-NH2 hydrochloride is a compound resulting from the synthesis of an E3 ligase ligand-linker conjugate. It combines the cereblon ligand derived from Pomalidomide with a 6-unit PEG linker. This compound is specifically designed for application in PROTAC technology.
T39953	Pomalidomide-amino-PEG3-NH2 hydrochloride Pomalidomide-amino-PEG3-NH2 hydrochloride
	Pomalidomide-amino-PEG3-NH2 hydrochloride is a synthetic conjugate compound incorporating the cereblon ligand from Pomalidomide and a linker commonly utilized in PROTAC technology. This compound functions as an E3 ligase ligand-linker conjugate in biochemical reactions.
T39867	Pomalidomide-amino-PEG4-NH2 hydrochloride Pomalidomide-amino-PEG4-NH2 hydrochloride
	Pomalidomide-amino-PEG4-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate, incorporates the cereblon ligand derived from Pomalidomide, along with a linker commonly employed in PROTAC technology.
T40078	(R)-Pomalidomide-pyrrolidine
	(R)-Pomalidomide-pyrrolidine, a CRBN ligand, can be conjugated to a protein-targeting ligand via a linker, resulting in the formation of PROTACs.
T40105	Pomalidomide-PEG3-C2-NH2 hydrochloride Pomalidomide-PEG3-C2-NH2 hydrochloride,Cereblon Ligand-Linker Conjugates 5 hydrochloride,E3ligaseLigand-LinkerConjugates30hydrochloride
	Pomalidomide-PEG3-C2-NH2 hydrochloride, also known as Cereblon Ligand-Linker Conjugate 5, is a chemically synthesized E3 ligase ligand-linker conjugate. This compound incorporates a cereblon ligand based on Pomalidomide and a linker commonly employed in PROTAC technology.
T30772	Pomalidomide-5-OH CC-17368,MVWWLCCKVBTYTD-UHFFFAOYSA-N,CC 17368,Pomalidomide metabolite M17,SCHEMBL15439650,CC17368
	CC-17368 is a bio-active chemical.
T69989	(S)-Pomalidomide
	(S)-Pomalidomide is an inhibitor of angiogenesis and growth of B-cell neoplasias, which induces complete regressions of Burkitt's lymphoma cell tumors.
T40010	Pomalidomide-C9-COOH	Others	Others
	Pomalidomide-C9-COOH 是一种合成的 E3 连接酶配体-接头偶联物，它结合了 PROTAC 技术中使用的基于 Pomalidomide 的 CRBN 配体和接头。
T18554	Pomalidomide-PEG1-azide	Others	Others
	Pomalidomide-PEG1-azide is an E3 ligase ligand-linker conjugate that combines the cereblon ligand based on Pomalidomide with a linker. This compound is instrumental in designing PROTAC BRD4 Degrader-1[1].
T18556	Pomalidomide-PEG4-azide	Others	Others
	Pomalidomide-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
T36262	Thalidomide-NH-C5-NH2 hydrochloride Pomalidomide 4'-alkylC5-amine
	Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC5 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Pomalidomide - linker 4 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

化合物

Cat.No: T2384

Synonym: CC-4047,泊马度胺

Target: Apoptosis, TNF, Ligand for E3 Ligase, Molecular Glues

Pomalidomide-PEG2-CO2H

Cat.No: T40025

Synonym: Pomalidomide 4'-PEG2-acid,Pomalidomide-PEG2-C2-acid

Target: E3 Ligase Ligand-Linker Conjugate

Pomalidomide-PEG1-CO2H

Cat.No: T40024

Synonym: Pomalidomide-PEG1-C2-COOH

Target: E3 Ligase Ligand-Linker Conjugate

Pomalidomide-C5-COOH

Cat.No: T40007

Target: Others

Pomalidomide-C4-COOH

Cat.No: T40009

Target: Others

Pomalidomide-C6-COOH

Cat.No: T40001

Target: Others

Pomalidomide-C4-OH

Cat.No: T40014

Target: Others

Pomalidomide-C2-COOH

Cat.No: T40005

Target: Others

Pomalidomide-C2-acid

Cat.No: T40020

Target: Others

Pomalidomide-C3-I

Cat.No: T40000

Target: Others

Pomalidomide-C7-NH2 hydrochloride

Cat.No: T40004

Target: Others

Pomalidomide-C6-I TFA

Cat.No: T40008

Target: Others

Pomalidomide-PEG2-NH2 hydrochloride

Cat.No: T40015

Target: Others

Pomalidomide-PEG3-CO2H

Cat.No: T40023

Synonym: Thalidomide-NH-PEG3-propionic acid

Target: E3 Ligase Ligand-Linker Conjugate

Pomalidomide 4'-PEG2-azide

Cat.No: T9387

Target: E3 Ligase Ligand-Linker Conjugate

Pomalidomide-CH2CONH-C2-COOH

Cat.No: T40006

Target: Others

Pomalidomide-C3-NH2 hydrochloride

Cat.No: T40002

Target: Others, E3 Ligase Ligand-Linker Conjugate

Pomalidomide-C2-NH2 hydrochloride

Cat.No: T7761

Target: E3 Ligase Ligand-Linker Conjugate, Ligand for E3 Ligase

Pomalidomide-PEG4-C2-NH2 hydrochloride

Cat.No: T40032

Target: PROTAC Linker

Pomalidomide-PEG4-C-COOH

Cat.No: T17325

Synonym: Cereblon Ligand -Linker Conjugates 1,E3 Ligase Ligand-Linker Conjugates 1

Target: Others, E3 Ligase Ligand-Linker Conjugate

Pomalidomide-PEG2-OH

Cat.No: T9383

Synonym: 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-(2-hydroxyethoxy)ethyl]amino]-

Target: PROTACs

Pomalidomide-PEG3-OH

Cat.No: T9384

Synonym: 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]amino]-

Target: PROTACs

Pomalidomide-PEG4-C2-NH2

Cat.No: T17916

Synonym: Cereblon Ligand-Linker Conjugates 8,E3 Ligase Ligand-Linker Conjugates 22

Target: Others, Ligand for E3 Ligase

Pomalidomide-PEG4-Ph-NH2

Cat.No: T7756

Target: Ligand for E3 Ligase

Pomalidomide-PEG3-azide

Cat.No: T39804

Synonym: Pomalidomide-PEG3-azide

Cat.No: T41163

Synonym: Pomalidomide-C3-adavosertib

Target: Apoptosis, Wee1

Pomalidomide-PEG2-azide

Cat.No: T39803

Synonym: Pomalidomide-PEG2-azide

Pomalidomide-C7-COOH

Cat.No: T39701

Synonym: Pomalidomide-C7-COOH

Pomalidomide-C4-NH2

Cat.No: T39381

Synonym: Pomalidomide-C4-NH2

Pomalidomide-5-O-CH3

Cat.No: T39032

Synonym: Pomalidomide-5-O-CH3

Pomalidomide-amino-PEG5-NH2 hydrochloride

Cat.No: T40085

Synonym: Pomalidomide-amino-PEG5-NH2 hydrochloride

Pomalidomide-C4-NH2 hydrochloride

Cat.No: T39636

Synonym: Pomalidomide-C4-NH2 hydrochloride

Pomalidomide 4'-PEG3-azide

Cat.No: T39806

Synonym: Pomalidomide 4'-PEG3-azide

Pomalidomide-amido-C3-COOH

Cat.No: T39637

Synonym: Pomalidomide-amido-C3-COOH

Pomalidomide 4'-alkylC8-acid

Cat.No: T36263

Synonym: Pomalidomide 4'-alkylC8-acid

Pomalidomide-6-O-CH3

Cat.No: T39033

Synonym: Pomalidomide-6-O-CH3

Pomalidomide-amino-PEG5-NH2

Cat.No: T40084

Synonym: Pomalidomide-amino-PEG5-NH2

Pomalidomide-amino-PEG4-NH2

Cat.No: T39866

Synonym: Pomalidomide-amino-PEG4-NH2

Pomalidomide-amino-PEG3-NH2

Cat.No: T39952

Synonym: Pomalidomide-amino-PEG3-NH2

Pomalidomide-PEG6-NH2 hydrochloride

Cat.No: T39875

Synonym: Pomalidomide-PEG6-NH2 hydrochloride

Pomalidomide-amino-PEG3-NH2 hydrochloride

Cat.No: T39953

Synonym: Pomalidomide-amino-PEG3-NH2 hydrochloride

Pomalidomide-amino-PEG4-NH2 hydrochloride

Cat.No: T39867

Synonym: Pomalidomide-amino-PEG4-NH2 hydrochloride

(R)-Pomalidomide-pyrrolidine

Cat.No: T40078

Pomalidomide-PEG3-C2-NH2 hydrochloride

Cat.No: T40105

Synonym: Pomalidomide-PEG3-C2-NH2 hydrochloride,Cereblon Ligand-Linker Conjugates 5 hydrochloride,E3ligaseLigand-LinkerConjugates30hydrochloride

Pomalidomide-5-OH

Cat.No: T30772

Synonym: CC-17368,MVWWLCCKVBTYTD-UHFFFAOYSA-N,CC 17368,Pomalidomide metabolite M17,SCHEMBL15439650,CC17368

(S)-Pomalidomide

Cat.No: T69989

Pomalidomide-C9-COOH

Cat.No: T40010

Target: Others

Pomalidomide-PEG1-azide

Cat.No: T18554

Target: Others

Pomalidomide-PEG4-azide

Cat.No: T18556

Target: Others

Thalidomide-NH-C5-NH2 hydrochloride

Cat.No: T36262

Synonym: Pomalidomide 4'-alkylC5-amine

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