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Cat. No. | Product Name | Target | Signaling Pathways |
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T1453 |
Phenformin hydrochloride
Phenformin HCl,Phenethylbiguanide hydrochloride,盐酸苯乙福明 |
Potassium Channel; AMPK; Autophagy | Autophagy; Chromatin/Epigenetic; Membrane transporter/Ion channel; PI3K/Akt/mTOR signaling |
Phenformin hydrochloride (Phenformin HCl) 是一种具有抗高血糖活性的双胍类抗糖尿病药物,能够使 AMPK 活化。 | |||
T20158 |
Phenformin
Debeone,N-Phenethylbiguanide,Insoral,BRN 1977317,Azucaps |
Apoptosis | Apoptosis |
Phenformin (BRN 1977317) 是一种双胍化合物,具有抗癌和抗血糖活性,抑制皮肤肿瘤生长并促进角质形成细胞分化,促进细胞凋亡。 |
Cat. No. | Product Name | Target | Signaling Pathways |
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T35532 |
Galegine hydrochloride
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Galegine hydrochloride, a guanidine derivative derived from G. officinalis, plays a role in inducing weight loss in mice and has contributed to the development of biguanides, including metformin and phenformin. This compound stimulates AMPK activation in 3T3-L1 adipocytes, L6 myotubes, H4IIE rat hepatoma, and HEK293 human kidney cell lines. Additionally, galegine hydrochloride exhibits antibacterial properties, particularly demonstrating a minimum inhibitory concentration of 4 mg/L against Staph... |