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15

抑制剂 & 化合物

3

天然产物

1

同位素

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Cat. No.	Product Name	Target	Signaling Pathways
T28777	Silicon Phthalocyanine 4 Pc-4,Pc 4,Pc4	Others	Others
	Silicon Phthalocyanine 4 is a drug with anti-cutaneous neoplasms activity.
T81477	Phytochelatin 4 PC 4
	Phytochelatin 4 (PC 4)为植物体内富含Cys的小分子短肽，其结构特征为含有γ-Glu-Cys基序。
T85003	1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC PC(18:0/22:4)	Others	Others
	1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC (PC(18:0/22:4)) 是一种抑制细胞周期蛋白依赖性激酶 (CDKs) 的化合物，能够诱导细胞凋亡 (apoptosis) 并阻止多种癌终细胞系的增殖。
T81476	Phytochelatin 4 TFA PC 4 TFA
	Phytochelatin 4 (PC 4) TFA，一种在植物中发现的短肽，富含 Cys，且具有 γ-Glu-Cys 基序。
T69379	Iproclozide	Others	Others
	Iproclozide is a potent monamine oxydase inhibitor (MAOI).
T18516	PC Alkyne-PEG4-NHS ester	Others	Others
	PC Alkyne-PEG4-NHS ester is a cleavable 4-unit PEG linker employed for the synthesis of antibody-drug conjugates (ADCs)[1].
T39446	PC DBCO-PEG4-NHS ester PC DBCO-PEG4-NHS ester	Others	Others
	PC DBCO-PEG4-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18520	PC-Biotin-PEG4-PEG3-azide	Others	Others
	PC-Biotin-PEG4-PEG3-azide is a cleavable 7-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker employed for the synthesis of ADCs [1].
T18519	PC-Biotin-PEG4-NHS carbonate	Others	Others
	PC-Biotin-PEG4-NHS carbonate is a polyethylene glycol (PEG) derived linker employed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
T17586	Biotin-PEG4-PC-PEG4-alkyne	Others	Others
	Biotin-PEG4-PC-PEG4-alkyne is a polyethylene glycol (PEG)-based proteolysis targeting chimera (PROTAC) linker utilized in the synthesis of PROTACs[1].
T18523	PC Methyltetrazine-PEG4-NHS carbonate ester	Others	Others
	PC Methyltetrazine-PEG4-NHS carbonate ester is a polyethylene glycol (PEG) derived linker specifically designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
T85255	1-Palmitoyl-2-Arachidonoyl-sn-glycero-3-PC 1-Palmitoyl-2-Arachidonoyl-sn-glycero-3-Phosphocholine,PC(16:0/20:4),PAPC	Others	Others
	1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PC (PAPC) is a phospholipid found in biological membranes, featuring palmitic acid (16:0) and arachidonic acid (20:4) at the sn-1 and sn-2 positions, respectively. PAPC undergoes oxidation in vivo, producing derivatives that play roles in chronic inflammation and vascular disease. Additionally, PAPC has been utilized in the investigation of oxidized phospholipid signaling mechanisms. Notably, PAPC levels are diminished in isolated human multiple myeloma ce...
T130784	6-(1-Hydroxypentyl)-4-methoxy-2H-pyran-2-one. PC	Others	Others
	6-(1-Hydroxypentyl)-4-methoxy-2H-pyran-2-one. PC 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T130784。
T77526	Pim-1 kinase inhibitor 4	Apoptosis; Pim	Apoptosis; Chromatin/Epigenetic; JAK/STAT signaling
	Pim-1 kinase inhibitor 4 是一种高效的 Pim-1 激酶抑制剂，IC50 值为 17.01 nM。Pim-1 kinase inhibitor 4 还具有抗氧化活性和潜在的抗癌活性，对 DPPH 有抑制作用。Pim-1 kinase inhibitor 4 促进 PC-3 细胞凋亡 (apoptosis)，对 PC-3 细胞生长有抑制作用，IC50 为 16 nM。Pim-1 kinase inhibitor 4 可用于研究前列腺癌。
T71252	PC-046	Others	Others
	PC-046 is a potent tubulin-binding agent, which was originally identified for development based on selective activity in deleted in pancreas cancer locus 4 (DPC4/SMAD4) deficient tumors. PC-046 has growth inhibitory activity in a variety of tumor types in vitro, and efficacy in SCID mice was shown in human tumor xenografts of MV-4-11 acute myeloid leukemia, MM.1S multiple myeloma, and DU-145 prostate cancer. Pharmacokinetic studies demonstrated relatively high oral bioavailability (71 %) with di...

化合物

Silicon Phthalocyanine 4

Cat.No: T28777

Synonym: Pc-4,Pc 4,Pc4

Target: Others

Phytochelatin 4

Cat.No: T81477

Synonym: PC 4

1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC

Cat.No: T85003

Synonym: PC(18:0/22:4)

Target: Others

Phytochelatin 4 TFA

Cat.No: T81476

Synonym: PC 4 TFA

Cat.No: T69379

Target: Others

PC Alkyne-PEG4-NHS ester

Cat.No: T18516

Target: Others

PC DBCO-PEG4-NHS ester

Cat.No: T39446

Synonym: PC DBCO-PEG4-NHS ester

Target: Others

PC-Biotin-PEG4-PEG3-azide

Cat.No: T18520

Target: Others

PC-Biotin-PEG4-NHS carbonate

Cat.No: T18519

Target: Others

Biotin-PEG4-PC-PEG4-alkyne

Cat.No: T17586

Target: Others

PC Methyltetrazine-PEG4-NHS carbonate ester

Cat.No: T18523

Target: Others

1-Palmitoyl-2-Arachidonoyl-sn-glycero-3-PC

Cat.No: T85255

Synonym: 1-Palmitoyl-2-Arachidonoyl-sn-glycero-3-Phosphocholine,PC(16:0/20:4),PAPC

Target: Others

6-(1-Hydroxypentyl)-4-methoxy-2H-pyran-2-one. PC

Cat.No: T130784

Target: Others

Pim-1 kinase inhibitor 4

Cat.No: T77526

Target: Apoptosis, Pim

Cat.No: T71252

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T4S2126	Ginkgetin 银杏双黄酮,银杏素	Apoptosis; Wnt/beta-catenin; COX; STAT; Autophagy	Apoptosis; Autophagy; Cytoskeletal Signaling; Immunology/Inflammation; JAK/STAT signaling; Neuroscience; Stem Cells
	Ginkgetin 是从银杏叶中分离得到的一种双黄酮，具有抗肿瘤、抗炎、神经保护、抗真菌的作用。它也是 Wnt 信号抑制剂，IC50值为 5.92 μM。
TN5682	2,6,4'-Trihydroxy-4-methoxybenzophenone
	2,6,4'-Trihydroxy-4-methoxybenzophenone shows weak inhibitory activity of testosterone 5alpha-reductase, it also shows significant inhibition of pancreatic lipase activity. 2,6,4'-Trihydroxy-4-methoxybenzophenone has neurotrophic activity, it induced neurite outgrowth in PC-12 cells at concentration of 50 microg/ml. 2,6,4â²-Trihydroxy-4-methoxybenzophenone exhibits low cytotoxic effect against HeLa and 3T3 cell lines with IC50 values of 132 ug/ml and 158 ug/ml, repectively. It also shows antiox...
T36845	Isogarcinol	Others	Others
	Isogarcinol is a natural polyisoprenylated benzophenone first isolated from plant species in the genus Garcinia. It has immunosuppressant actions, inhibiting the protein phosphatase calcineurin (IC50 = 36 μM) and suppressing the proliferation of T cells. Oral administration of isogarcinol in mice decreases delayed type hypersensitivity, prolongs graft survival in allogeneic skin transplants, suppresses inflammation in collagen-induced arthritis, and reduces clinical symptoms in experimental auto...

天然产物

Cat.No: T4S2126

Synonym: 银杏双黄酮,银杏素

Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy

2,6,4'-Trihydroxy-4-methoxybenzophenone

Cat.No: TN5682

Cat.No: T36845

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T38356	1,2-Dipalmitoyl-13C-sn-glycero-3-PC
	1,2-Dipalmitoyl-13C-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes for use in a variety of applications.1,2,3,4 It has been used in the formation of proteoliposomes for implantation of γ-glutamyl transpeptidase into human erythrocyte membranes.3 Incorporation...

同位素

1,2-Dipalmitoyl-13C-sn-glycero-3-PC

Cat.No: T38356

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