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Cat. No. | Product Name | Target | Signaling Pathways |
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T19950 |
Paliperidone Palmitate
RO 92670,RO92670,RO-92670 |
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Paliperidone is a dopamine antagonist and 5-HT2A antagonist of the atypical antipsychotic class of medications. Paliperidone has an antagonist effect at α1 and α2 adrenergic receptors and at H1 histamine receptors. In addition, it binds with dopamine and |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0076 |
Paliperidone
9-羟基利培酮,帕潘立酮,9-hydroxyrisperidone |
Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Paliperidone (9-hydroxyrisperidone) 是 Risperidone 的主要活性代谢产物,是多巴胺 D2 拮抗剂和5-HT2A 拮抗剂。它用作非典型抗精神病药,用于精神分裂症的急性及维持治疗。它对α1和α2肾上腺素能受体和 H1组胺能受体也有拮抗作用。 |