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Targets Recommended: PDK

3

抑制剂 & 化合物

9

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T16670 PS210

PDK PI3K/Akt/mTOR signaling
PS210 是针对 PDK1的 PIF 结合口袋的、选择性的、有效的 PDK1激活剂,对其他蛋白激酶无活性。在细胞中,它的前药 PS423 可作为 PDK1的底物选择性抑制剂,抑制 S6K 的磷酸化和活化。
T3094 PS-1145

IKK Inhibitor X

Apoptosis; B/IKK Apoptosis; NF-κB
PS-1145 (IKK Inhibitor X) 是一种 IκB 激酶抑制剂,IC50为 88 nM。
T65387 Paromomycin, sulfate (1:1)

Paromomycin (Sulfate Salt) is an aminoglycoside that is active against Gram-negative and many Gram-positive bacteria as well as some protozoa and cestodes. Paromomycin in combination with sodium stibogluconate has proven to be effective in African and Indian VL (visceral leishmaniasis) and improves survival in African VL[3]. PS (Paromomycin Sulfate) is effective for elimination of B. coli without hematological side effects[4]. The activity of phosphoglucose isomerase was slightly inhibited by 10...

化合物

PS210
Cat.No: T16670
Synonym:
Target: PDK
PS-1145
Cat.No: T3094
Synonym: IKK Inhibitor X
Target: Apoptosis, IκB/IKK
Paromomycin, sulfate (1:1)
Cat.No: T65387
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-00522 PSG9 Protein, Human, Recombinant (His)

PS-β-G-11,PS-β-G-9,PS-β-B...

Human HEK293 Cells
Pregnancy-specific beta-1-glycoprotein 9(PSG9) is a secreted protein and contains 3 Ig-like C2-type (immunoglobulin-like) domains, 1 Ig-like V-type (immunoglobulin-like) domain. It is a member of the PSG family, a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. The members of the PSG protein family all have a characteristic N-terminal domain that is homologous to the immunoglobulin variable region. PSGs become detectable in ...
TMPY-01589 Serpin B10 Protein, Mouse, Recombinant (His)

Serpinb10-ps,serpin peptidase inh...

Mouse Baculovirus Insect Cells
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhi...
TMPY-00551 PSG1 Protein, Human, Recombinant (hFc)

PSGIIA,PS-β-C/D,FL-NCA-1/2,PS...

Human HEK293 Cells
PSG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.2 kDa and the accession number is P11464-1.
TMPY-00552 PSG1 Protein, Human, Recombinant (His)

PS-β-G-1,PSBG-1,PS

Human HEK293 Cells
PSG1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.9 kDa and the accession number is P11464-1.
TMPJ-01135 PSG3 Protein, Human, Recombinant (His)

PS-Beta-G-3,Pregnancy-specific β-...

Human HEK293 Cells
Pregnancy-specific beta-1-glycoprotein 3 is also known as Carcinoembryonic Antigen SG5,Pregnancy-Specific Glycoprotein 3 ,PS-Beta-G-3, PSBG-3.It belongs to the immunoglobulin superfamily. CEA family.It synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular Cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, Members of the CEA family consist o...
TMPJ-00506 PSG5 Protein, Human, Recombinant (His)

PSBG-5,FL-NCA-3,Pregnancy-specifi...

Human HEK293 Cells
Pregnancy-specific beta-1-glycoprotein 5, is a secreted protein which belongs to the immunoglobulin superfamily, CEA family. It contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain.
TMPK-01413 H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi)

H-2K,OVA,MHC,H2-K1

Mouse HEK293 Cells
Ovalbumin (OVA) has been historically a popular source of such antigens, since OVA can induce both humoral and cellular immune responses based on well-characterised peptide epitopes. The OVA257-264 octapeptide was one of the frst OVA epitopes to be characterised, it has an amino acid sequence SIINFEKL, which is recognised by cytotoxic T lymphocytes. SIINFEKL forms fbrillar assemblies similar to other peptide hydrogels. Te immunoactive properties of this peptide can therefore be related to its se...
TMPK-01412 HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi)

SARS-CoV-2 epitope,MHC

Human HEK293 Cells
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype.
TMPK-01416 HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated

MHC,SARS-CoV-2 epitope

Human HEK293 Cells
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype.

重组蛋白

PSG9 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00522
Species: Human
Expression System: HEK293 Cells
Serpin B10 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01589
Species: Mouse
Expression System: Baculovirus Insect Cells
PSG1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00551
Species: Human
Expression System: HEK293 Cells
PSG1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00552
Species: Human
Expression System: HEK293 Cells
PSG3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01135
Species: Human
Expression System: HEK293 Cells
PSG5 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00506
Species: Human
Expression System: HEK293 Cells
H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi)
Cat.No: TMPK-01413
Species: Mouse
Expression System: HEK293 Cells
HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01412
Species: Human
Expression System: HEK293 Cells
HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01416
Species: Human
Expression System: HEK293 Cells
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