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Cat. No.	Product Name	Target	Signaling Pathways
T61465	PPARγ agonist 3
	PPARγ agonist 3, also known as Compound 18a, is a potent and selective agonist of PPARγ. This compound does not exhibit cytotoxicity towards both non-resistant and resistant cells. Notably, PPARγ agonist 3 demonstrates antitumor efficacy exclusively when co-administered with Imatinib [1].
T12835	Saroglitazar Lipaglyn	PPAR	DNA Damage/DNA Repair; Metabolism
	Saroglitazar (Lipaglyn) 是 PPAR 的激动剂，对 PPARα 和 PPARγ 的 EC50 值为 0.65 pM 和 3 nM。
T12834	Saroglitazar Magnesium	Others	Others
	Saroglitazar Magnesium 是一种新型过氧化物酶体增殖物激活受体(PPAR)激动剂，对PPARα （EC50 0.65pM）具有显著的激活活性以及对PPARγ（EC50 3 nM）有中等的激活活性。
T19710	Ciglitazone Ciglitazona,U 63287,ADD3878,ADD-3878,U-63287,ADD 3878	Apoptosis; p38 MAPK; PPAR	Apoptosis; DNA Damage/DNA Repair; MAPK; Metabolism
	Ciglitazone (ADD 3878) 是一种强效和选择性的PPARγ激动剂(EC50：3μM)和口服降糖药。Ciglitazone 抑制th17细胞的增殖和分化，降低胰岛素水平、血管内皮生长因子的产生和血压，诱导胃癌细胞的细胞周期停止。Ciglitazone 能诱导负鼠肾上皮细胞的凋亡，激活p38 MAPK 和凋亡诱导因子(AIF)的核转位。 Ciglitazone 在肥胖症和高血糖症的动物模型中表现出降血糖活性。
T61836	Pioglitazone potassium
	Pioglitazone potassium (U 72107) is an orally active and selective agonist of peroxisome proliferator-activated receptor gamma (PPARγ). It demonstrates high affinity binding to the ligand-binding domain of PPARγ, with an EC50 of 0.93 μM and 0.99 μM for human and mouse PPARγ, respectively. Pioglitazone potassium has applications in diabetes research [2] [3] [4].
TMIH-0516	Saroglitazar-d4
	Saroglitazar-d4 是 Saroglitazar 的氘代化合物。Saroglitazar 的 CAS 号为 495399-09-2。Saroglitazar 是 PPAR 的激动剂，对 PPARα 和 PPARγ 的 EC50 值为 0.65 pM 和 3 nM。
TMIH-0517	Saroglitazar oxide-d4
	Saroglitazar oxide-d4 是 Saroglitazar oxide 的氘代化合物。Saroglitazar oxide 的 CAS 号为 495399-09-2。Saroglitazar 是 PPAR 的激动剂，对 PPARα 和 PPARγ 的 EC50 值为 0.65 pM 和 3 nM。
T37634	17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
	Docosapentaenoic acid (DPA) is a ω-3 fatty acid found in fish oils. 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DPA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARγ agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 μM).
T35468	(±)19(20)-EDP Ethanolamide
	(±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively). It is produced through direct epoxygenation of docosahexaenoyl ethanolamide by cytochrome P450 (CYP) epoxygenases. (±)19(20)-EDP ethanolamide (25 μM) reduces the viability of 143B metastatic osteosarcoma cells. It decreases the production of IL-6 and increases the production of IL-10 when used at concentrations ranging from 2.5 to 10 μM in BV-...
T65598	Cefminox sodium
	Cefminox (Sodium) is a new cephamycin antibiotic possessing a D-amino acid moiety derived from D-cysteine at the C-7B side chain. Cefminox is active against a wide range of bacteria, especially Gram-negative and anaerobic bacteria. Cefminox shows excellent in vivo efficacy (ED50) which is higher than would be expected from its in vitro activity (MIC). Moreover, cefminox possesses more potent activity in suppression of bacterial regrowth than other cephems[1]. Cefminox (Sodium) was the most activ...

化合物

Synonym: Lipaglyn

Target: PPAR

Saroglitazar Magnesium

Synonym: Ciglitazona,U 63287,ADD3878,ADD-3878,U-63287,ADD 3878

Target: Apoptosis, p38 MAPK, PPAR

Pioglitazone potassium

Cat.No: TMIH-0516

Synonym:

Target:

Saroglitazar oxide-d4

Cat.No: TMIH-0517

Synonym:

Target:

17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid

Cat.No: T37634

Synonym:

Target:

(±)19(20)-EDP Ethanolamide

Cat. No.	Product Name	Target	Signaling Pathways
TN7060	Methyl oleanonate	PPAR	DNA Damage/DNA Repair; Metabolism
	Methyl oleanonate 是从柃木中分离得到的一种三萜类天然产物，是齐墩果酸衍生物，是一种PPARγ激动剂，具有抗癌作用。

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