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Search Results for " pdcd1 "

5

抑制剂 & 化合物

12

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T82465	Enlonstobart
	Enlonstobart为一种人源化免疫球蛋白G4-kappa类抗PDCD1单克隆抗体，兼具免疫刺激剂与抗肿瘤药物的双重功能。
T81928	Lipustobart	PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
	Lipstobart是一种IgG4-kappa型抗PDCD1(程序性细胞死亡1, PD1,PD-1, CD279)的人源化单克隆抗体，具有免疫刺激和抗肿瘤活性。
T78322	Lesabelimab LDP
	Lesabelimab（LDP）是一种针对CD274的免疫球蛋白G1-kappa型单克隆抗体。CD274作为免疫检查点配体，能够通过与PDCD1受体的结合，抑制肿瘤的免疫反应。
T77040	Iparomlimab
	Iparomlimab 是一种 IgG4κ 抗体，抗人 PD-1/CD279/PDCD1，并靶向人单克隆 PSB103 γ4 链，形成二硫键二聚体。适用于肿瘤学研究。
T82508	Eciskafusp alfa	PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
	Eciskafusp alfa是一种针对程序性细胞死亡1(PDCD1，亦称PD-1)的顺式靶向IL2v免疫细胞因子。它优先选择抗原特异性干细胞样PD-1+ TCF-1+ CD8+ T细胞，并促使这些细胞分化成更高效的效应器细胞。Eciskafusp alfa主要用于癌症与慢性感染的研究领域。

化合物

Cat.No: T82465

Cat.No: T81928

Target: PD-1/PD-L1

Cat.No: T78322

Synonym: LDP

Cat.No: T77040

Eciskafusp alfa

Cat.No: T82508

Target: PD-1/PD-L1

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00180	PD-1 Protein, Human, Recombinant (aa 25-167, hFc & Avi), Biotinylated PD-1,PDCD1,CD279,SLEB2,PD1	Human	HEK293 Cells
	Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity. PD-1 Protein, Human, Recombinant (aa 25-167, hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 44.7 kDa and the accession nu...
TMPK-00181	PD-1 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated SLEB2,PD-1,PDCD1,PD1,CD2...	Mouse	HEK293 Cells
	Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity. PD-1 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 42.9 kDa and the accessio...
TMPK-00688	PD-1 Protein, Canine, Recombinant (aa 25-170, hFc) CD279,PDCD1,SLEB2,PD1,PD-1	Canine	HEK293 Cells
	Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity. PD-1 Protein, Canine, Recombinant (aa 25-170, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 43.00 kDa and the accession number is A0A090BAM7.
TMPJ-00181	PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated Programmed cell death protein 1,PDCD1<...	Human	HEK293 Cells
	Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PDCD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. PDCD1 has been sugg...
TMPK-01290	PD-L2 Protein, Cynomolgus, Recombinant (aa 20-220, His) B7DC,PDL2,CD273, PDCD1 ligand 2,Btdc,P...	Cynomolgus	HEK293 Cells
	PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals. PD-L2 Protein, Cynomolgus, Recombinant (aa 20-220, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 23.73 kDa and the acces...
TMPK-00166	PD-L2 Protein, Human, Recombinant (His & Avi) PDL2,Btdc,Butyrophilin B7-DC,PDCD1LG2,bA57...	Human	HEK293 Cells
	PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals. PD-L2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.3 kDa and the accession nu...
TMPJ-00182	PD-L1 Protein, Human, Recombinant (hFc & Avi), Biotinylated B7-H1,PDCD1LG1,PD-L1...	Human	HEK293 Cells
	PD-L1 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 70-95 KDa and the accession number is Q9NZQ7.
TMPJ-00183	PD-L1 Protein, Human, Recombinant (Flag) B7-H1,Programmed Cell Death 1 Ligand 1...	Human	HEK293 Cells
	PD-L1 Protein, Human, Recombinant (Flag) is expressed in HEK293 mammalian cells with C-Flag tag. The predicted molecular weight is 35-40 KDa and the accession number is Q9NZQ7.
TMPJ-01300	PDCD10 Protein, Human, Recombinant TFAR15,Programmed Cell Death Protein 10,	Human	E. coli
	Programmed Cell Death Protein 10 (PDCD10) belongs to the PDCD10 family. PDCD10 exists as a homodimer and is widely expressed. PDCD10 can increase mitogen-activated protein kinase activity and MST4 activity. PDCD10 is required for normal cardiovascular development and normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development. Defects in PDCD10 are the cause of cerebral cavernous malformations type 3.
TMPH-01913	PDCD10 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	PDCD10 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPK-00662	PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus macaque, Recombinant (His), Biotinylated PDCD1LG1,B7-H1,B7H1<...	Cynomolgus,Rhesus	HEK293 Cells
	B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus macaque, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His t...
TMPK-00182	PD-L1 Protein, Human, Recombinant (aa 19-238, His & Avi), Biotinylated PDL1,PD-L1B7 homolog 1,PD-L1<...	Human	HEK293 Cells
	B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1 Protein, Human, Recombinant (aa 19-238, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecu...

重组蛋白

PD-1 Protein, Human, Recombinant (aa 25-167, hFc & Avi), Biotinylated

Cat.No: TMPK-00180

Species: Human

Expression System: HEK293 Cells

PD-1 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated

Cat.No: TMPK-00181

Species: Mouse

Expression System: HEK293 Cells

PD-1 Protein, Canine, Recombinant (aa 25-170, hFc)

Cat.No: TMPK-00688

Species: Canine

Expression System: HEK293 Cells

PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00181

Species: Human

Expression System: HEK293 Cells

PD-L2 Protein, Cynomolgus, Recombinant (aa 20-220, His)

Cat.No: TMPK-01290

Species: Cynomolgus

Expression System: HEK293 Cells

PD-L2 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00166

Species: Human

Expression System: HEK293 Cells

PD-L1 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPJ-00182

Species: Human

Expression System: HEK293 Cells

PD-L1 Protein, Human, Recombinant (Flag)

Cat.No: TMPJ-00183

Species: Human

Expression System: HEK293 Cells

PDCD10 Protein, Human, Recombinant

Cat.No: TMPJ-01300

Species: Human

Expression System: E. coli

PDCD10 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01913

Species: Human

Expression System: E. coli

PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus macaque, Recombinant (His), Biotinylated

Cat.No: TMPK-00662

Species: Cynomolgus,Rhesus

Expression System: HEK293 Cells

PD-L1 Protein, Human, Recombinant (aa 19-238, His & Avi), Biotinylated

Cat.No: TMPK-00182

Species: Human

Expression System: HEK293 Cells

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