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Cat. No.	Product Name	Target	Signaling Pathways
T38836L	Protease-Activated Receptor-1, PAR-1 Agonist acetate	Protease-activated Receptor	GPCR/G Protein
	Protease-Activated Receptor-1, PAR-1 Agonist acetate 是一种选择性蛋白酶激活受体 1 (PAR-1) 激动剂肽。它对应于 PAR1 栓系配体，可以选择性地模拟凝血酶通过该受体的作用。
T12870	SCH79797 dihydrochloride	Apoptosis; Others; Protease-activated Receptor	Apoptosis; GPCR/G Protein; Others
	SCH79797 dihydrochloride 是一种有效的特异性蛋白酶激活受体 1 (PAR1) 拮抗剂，IC50 为 70 nM，Ki 为 35 nM。SCH79797 dihydrochloride 具有抗增殖和促凋亡作用。
T1893	Parmodulin 2 ML 161	Protease-activated Receptor	GPCR/G Protein
	Parmodulin 2 (ML 161) 是一种蛋白酶激活受体 1(PAR1) 变构抑制剂，IC50为 0.26 μM。它是蛋白酶激活受体 1 (PAR1) 介导的血小板活化的抑制剂，可以抑制体外血小板聚集和体内血小板血栓形成。
T7625	TRAP-6 PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6,TRAP-6(2TFA)	Protease-activated Receptor	GPCR/G Protein
	TRAP-6 (Thrombin Receptor Activator Peptide 6) 是一种多肽片段，是选择性的蛋白酶激活受体 1 (PAR1) 激动剂，通过凝血酶受体激活人血小板。
T38836	Protease-Activated Receptor-1, PAR-1 Agonist
	Protease-Activated Receptor-1 (PAR-1) Agonist, a selective peptide, activates the PAR-1 receptor by mimicking the specific actions of thrombin. It corresponds to the PAR1 tethered ligand, facilitating selective activation of this receptor.
T36288	Protease-Activated Receptor-1, PAR-1 Agonist TFA
	Protease-Activated Receptor-1 (PAR-1) Agonist TFA is a selective peptide that acts as an agonist for the proteinase-activated receptor-1 (PAR-1). Corresponding to the tethered ligand of PAR-1, this compound mimics the actions of thrombin through the PAR-1 receptor[1][2].
T7573L	TFLLR-NH2 2TFA(197794-83-5(free base))	Protease-activated Receptor	GPCR/G Protein
	TFLLR-NH2 2TFA(197794-83-5(free base)) 是 PAR1 (EC50 :1.9 μM) 的激动剂。
T7573	TFLLR-NH2 TFLLR-NH2(2TFA)	Protease-activated Receptor	GPCR/G Protein
	TFLLR-NH2 是选择性的一种PAR1激动剂，EC50值为1.9 μM。
T3098	Vorapaxar sulfate SCH 530348 sulfate,Zontivity,vorapaxar monosulfate,沃拉帕沙	Protease-activated Receptor	GPCR/G Protein
	Vorapaxar sulfate (Zontivity) 是一种选择性、口服活性和竞争性的凝血酶受体蛋白酶激活受体(PAR-1)拮抗剂，Ki 值为 8.1 nM。它剂量依赖性抑制凝血酶受体激活肽 (TRAP) 诱导的血小板聚集，是抗血小板药物。
T23282	RWJ-56110	Others	Others
	protease-activated receptor-1 (PAR1) antagonist
T71109	BAY-386
	BAY-386 is a PAR1 receptor inhibitor which suppresses activation of thrombin and platelet activity.
T23208	Q94 hydrochloride	Others	Others
	PAR1 negative allosteric modulator
T7013	Vorapaxar SCH 530348,MK-5348,沃拉帕沙	Protease-activated Receptor	GPCR/G Protein
	Vorapaxar (MK-5348) 是抗血小板药物，是一种选择性、口服活性和竞争性的凝血酶受体蛋白酶激活受体(PAR-1)拮抗剂，Ki 值为 8.1 nM。它靠剂量依赖性抑制凝血酶受体激活肽 (TRAP) 诱导的血小板聚集。
T28734	SCH79797 SCH 79797,SCH-79797
	SCH-79797 is a potent and selective PAR1 antagonist.
T28477	PZ-128 PZ 128
	PZ-128, a PAR1 antagonist, is used potentially for the treatment of thrombosis.
TP1334	TFLLR-NH2(TFA)
	TFLLR-NH2 (TFA) is a selective PAR1 agonist with an EC50 of 1.9 μM. EC50: 1.9 μM (PAR1)
T35867	TRAP-6 Peptide (trifluoroacetate salt)
	TRAP-6 peptide is a hexapeptide corresponding to residues 42-47 of protease-activated receptor 1 (PAR1). It acts as an agonist of PAR1, inducing platelet aggregation in human platelet-rich plasma ex vivo (EC50 = 0.8 μM). TRAP-6 (0.3 and 0.6 mg/kg) has a triphasic effect on mean arterial blood pressure (MAP) in anesthetized rats with a short decrease, an increase, and then a longer decrease in MAP following intravenous administration.
T78545	FLLRN TRAP-6 (2-6)
	FLLRN是一种具有生物活性的(PAR1特异性拮抗肽)。
T26744	BAY-598 R-isomer BAY598 R-isomer,BAY 598 R-isomer
	BAY-598 R-异构体是BAY589的R-异构体，它可用作参考化合物。它是是赖氨酸N-甲基转移酶（SMYD2）的抑制剂，对SMYD2比蛋白酶激活的受体1（PAR1）具有选择性。
T23237	RLLFT-NH2	Others	Others
	TFLLR-NH2, reversed amino acid sequence control peptide, is a PAR1 selective agonist that significantly increases the nociceptive threshold.
TP1965	Parstatin(human) Parstatin (human)
	Cell-permeable peptide cleaved from protease-activated receptor 1 (PAR1) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC50 ~ 3 μM), and induces cell cycle arrest. Promotes activation of caspase-3 and exhibits pro-apop
TP1966	Parstatin(mouse) Parstatin (mouse)
	Cell-permeable peptide cleaved from protease-activated receptor 1 (PAR1) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC50 ~ 20 μM), and induces cell cycle arrest. Promotes activation of caspase-3 and exhibits pro-apo
T80111	TRAP-5 amide
	TRAP-5 amide为蛋白酶激活受体1（PAR1）特异性的激动剂肽。
T36717	RWJ-56110 dihydrochloride
	RWJ-56110 dihydrochloride is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4. RWJ-56110 dihydrochloride inhibits the aggregation of human platelets induced by both SFLLRN-NH2 (IC50=0.16 μM) and thrombin (IC50=0.34 μM), quite selective relative to U46619 . RWJ-56110 dihydrochloride blocks angiogenesis and blocks the formation of new vessels in vivo. RWJ-56110 dihydrochloride induces cell ap...

化合物

Protease-Activated Receptor-1, PAR-1 Agonist acetate

Cat.No: T38836L

Target: Protease-activated Receptor

SCH79797 dihydrochloride

Cat.No: T12870

Target: Apoptosis, Others, Protease-activated Receptor

Cat.No: T1893

Synonym: ML 161

Target: Protease-activated Receptor

Cat.No: T7625

Synonym: PAR-1 agonist peptide,Thrombin Receptor Activator Peptide 6,TRAP-6(2TFA)

Target: Protease-activated Receptor

Protease-Activated Receptor-1, PAR-1 Agonist

Cat.No: T38836

Protease-Activated Receptor-1, PAR-1 Agonist TFA

Cat.No: T36288

TFLLR-NH2 2TFA(197794-83-5(free base))

Cat.No: T7573L

Target: Protease-activated Receptor

Cat.No: T7573

Synonym: TFLLR-NH2(2TFA)

Target: Protease-activated Receptor

Vorapaxar sulfate

Cat.No: T3098

Synonym: SCH 530348 sulfate,Zontivity,vorapaxar monosulfate,沃拉帕沙

Target: Protease-activated Receptor

Cat.No: T23282

Target: Others

Cat.No: T71109

Q94 hydrochloride

Cat.No: T23208

Target: Others

Cat.No: T7013

Synonym: SCH 530348,MK-5348,沃拉帕沙

Target: Protease-activated Receptor

Cat.No: T28734

Synonym: SCH 79797,SCH-79797

Cat.No: T28477

Synonym: PZ 128

Cat.No: TP1334

TRAP-6 Peptide (trifluoroacetate salt)

Cat.No: T35867

Cat.No: T78545

Synonym: TRAP-6 (2-6)

BAY-598 R-isomer

Cat.No: T26744

Synonym: BAY598 R-isomer,BAY 598 R-isomer

Cat.No: T23237

Target: Others

Parstatin(human)

Cat.No: TP1965

Synonym: Parstatin (human)

Parstatin(mouse)

Cat.No: TP1966

Synonym: Parstatin (mouse)

Cat.No: T80111

RWJ-56110 dihydrochloride

Cat.No: T36717

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