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Cat. No.	Product Name	Target	Signaling Pathways
TP1046L	PAR-2 Activating Peptide acetate SLIGRL-NH2 acetate,PAR-2 Activating Peptide acetate(171436-38-7 free base),Protease-Activated Receptor-2 Activating Peptide acetate	Protease-activated Receptor	GPCR/G Protein
	PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate)(171436-38-7 free base) 是 Protease-Activated Receptor-2 (PAR-2) 的激动剂。
T8917	PAR-2-IN-1 IUN76750,8-(叔丁基)-6-氯咪唑并[1,2-B]吡啶-2-羧酸甲酯	Protease-activated Receptor	GPCR/G Protein
	PAR-2-IN-1 (IUN76750) 是一种 PAR-2 信号通路抑制剂，具有抗炎和抗癌作用。
TP1046	SLIGRL-NH2 Protease-Activated Receptor-2 Activating Peptide	Protease-activated Receptor	GPCR/G Protein
	SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) 为一种蛋白酶激活受体-2 (PAR-2) 激动剂，具有诱导非组胺能性瘙痒的功能。
T1893	Parmodulin 2 ML 161	Protease-activated Receptor	GPCR/G Protein
	Parmodulin 2 (ML 161) 是一种蛋白酶激活受体 1(PAR1) 变构抑制剂，IC50为 0.26 μM。它是蛋白酶激活受体 1 (PAR1) 介导的血小板活化的抑制剂，可以抑制体外血小板聚集和体内血小板血栓形成。
T23189	prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens]	Others	Others
	Prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] is a peptide with the sequence H2N-Ala-Thr-Gly-Gly-Tyr-Arg-OH, MW= 623.66.
T36531	PAR2 (1-6) (mouse, rat) PAR2 (1-6) (mouse, rat)
	PAR2 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse and rat PAR2. It also corresponds to residues 39-44 and 37-42 of the mouse and rat full-length sequences, respectively. PAR2 (1-6) induces relaxation in precontracted rat arteries in a concentration-dependent manner, an effect that can be reduced by the nitric oxide synthase inhibitor L-NNA . It inhibits keratinocyte growth i...
T7513	Protease-Activated Receptor-2, amide 蛋白酶活化的受体-2，酰胺,SLIGKV-NH2,H-丝氨酰亮氨酰异亮氨酰甘氨酰赖氨酰缬氨酰NH2	Protease-activated Receptor	GPCR/G Protein
	Protease-Activated Receptor-2, amide (SLIGKV-NH2) 是 PAR2 的激动剂，IC50为 10.4 M。
T35955	PAR2 (1-6) amide (human) (trifluoroacetate salt) PAR2 (1-6) amide (human) (trifluoroacetate salt)
	PAR2 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR2 and residues 37-42 of the full-length sequence.1It binds to NCTC 2544 cells expressing human PAR2 (Ki= 9.64 μM in a radioligand binding assay) and induces calcium mobilization in the same cells (EC50= 0.075 μM).2PAR2 (1-6) amide (100 μM) reduces colony formation of A549 lung cancer cells.1It induces superoxide prod...
T76650	PAR-2 (1-6) (human)
	PAR-2 (1-6) (human) (SLIGKV) 是 PAR-2的多肽激动剂。
T28281	OXSI-2 OXSI 2,Syk Inhibitor	Syk	Angiogenesis; Tyrosine Kinase/Adaptors
	OXSI-2 (Syk Inhibitor) 是 Syk 的抑制剂，EC50 为 313 nM，IC50 为 14 nM。 OXSI-2 完全抑制适配器蛋白 LAT Y191 磷酸化和 Syk 介导的血小板聚集。
T7573	TFLLR-NH2 TFLLR-NH2(2TFA)	Protease-activated Receptor	GPCR/G Protein
	TFLLR-NH2 是选择性的一种PAR1激动剂，EC50值为1.9 μM。
TP1065	PAR-4 Agonist Peptide, amide TFA PAR-4-AP (TFA),AY-NH2 (TFA)	Protease-activated Receptor	GPCR/G Protein
	PAR-4 Agonist Peptide, amide TFA (PAR-4-AP (TFA)) 是一种蛋白酶激活受体 4 (PAR-4) 激动剂，对 PAR-1 或 PAR-2 均无影响，其作用可被 PAR-4 拮抗剂阻断。
T38836L	Protease-Activated Receptor-1, PAR-1 Agonist acetate	Protease-activated Receptor	GPCR/G Protein
	Protease-Activated Receptor-1, PAR-1 Agonist acetate 是一种选择性蛋白酶激活受体 1 (PAR-1) 激动剂肽。它对应于 PAR1 栓系配体，可以选择性地模拟凝血酶通过该受体的作用。
T22933L	LRGILS-NH2 acetate	Protease-activated Receptor	GPCR/G Protein
	LRGILS-NH2 acetate 是一种 PAR-2 失活的反向肽。
T27267	ENMD-1068 HCl ENMD-1068 HCl,ENMD 1068,ENMD-1068,ENMD1068,ENMD-1068 hydrochloride	Protease-activated Receptor	GPCR/G Protein
	ENMD-1068 HCl (ENMD 1068) 是一种选择性蛋白酶激活受体（PAR-2）拮抗剂，具有抗血管生成和抗炎活性。
TP2494	Acetyl Hexapeptide-49 Acetate Acetyl Hexapeptide-49 Acetate(1459205-54-9 Free base)	Others	Others
	Acetyl Hexapeptide-49 Acetate 可改善敏感皮肤因 PAR-2 诱导的促炎介质释放而出现的持续性疼痛和瘙痒的不适，此外还能恢复受损的屏障完整性。
T36286	Protease-Activated Receptor-3 (PAR-3) (1-6), human
	TFRGAP-amide, human PAR-3-derived tethered ligand sequence which does not activate PAR-3 but rather activates PAR-1 and PAR-2, either in Jurkat or in other PAR-expressing cells.
T36288	Protease-Activated Receptor-1, PAR-1 Agonist TFA
	Protease-Activated Receptor-1 (PAR-1) Agonist TFA is a selective peptide that acts as an agonist for the proteinase-activated receptor-1 (PAR-1). Corresponding to the tethered ligand of PAR-1, this compound mimics the actions of thrombin through the PAR-1 receptor[1][2].
T7623	PAR-4 Agonist Peptide, amide AY-NH2,PAR-4 Agonist Peptide, amide(2TFA),PAR-4-AP	Protease-activated Receptor	GPCR/G Protein
	PAR-4 Agonist Peptide, amide (AY-NH2) 是蛋白酶激活受体 4 (PAR-4) 的激动剂，对 PAR-1 或 PAR-2 均无影响，其作用可被 PAR-4 拮抗剂阻断。
T75902	SLIGRL-NH2 TFA Protease-Activated Receptor-2 Activating Peptide TFA
	SLIGRL-NH2 TFA（Protease-Activated Receptor-2 Activating Peptide TFA）作为PAR-2（蛋白酶激活受体-2）的激动剂，具有高度特异性。
T80240	Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2
	Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2是一类具有生物活性的肽，作为蛋白酶激活受体1 (PAR-1) 的选择性激动剂，其特异性优于PAR-2。该肽通过HEK293细胞进行的基于细胞的钙信号传导测定确认了其对PAR-1的高特异性，并可用于研究PAR-1在体内的激活。PAR-1除了介导凝血酶的多种细胞作用外，还与PAR-4协作，参与调控凝血酶诱导的被分类为“凝血型”的肝细胞癌。
T36293	PAR 4 (1-6)
	PAR 4 (1-6) 可用于生命科学领域的相关研究。其产品编号为 T36293，CAS号为 225779-44-2。
T75872	Parstatin(mouse) TFA
	Parstatin(mouse) TFA 是具有细胞通透性的 PAR-1凝血酶受体的肽类激动剂，是一种有效的血管生成抑制剂。
T75873	Parstatin(human) TFA
	Parstatin(human) TFA 是具有细胞通透性的 PAR-1凝血酶受体的肽类激动剂，是一种有效的血管生成抑制剂。
T27708	K-14585
	K-14585 is a proteinase-activated receptor 2 antagonist. K-14585 inhibited PAR(2)-mediated p65 NFkappaB phosphorylation and NFkappaB-DNA binding. K-14585 inhibited SLIGKV-stimulated IL-8 production, but given alone increased IL-8.
T64285	Protease-Activated Receptor-1 antagonist 2
	Protease-Activated Receptor-1 antagonist 2 是一种选择性的、口服具有活力的蛋白酶激活受体-1 (PAR-1) 拮抗剂 (IC50: 7 nM)。Protease-Activated Receptor-1 antagonist 2 显示出良好的药代动力学特性，能够用于进行心血管疾病 (CVD) 的相关研究（如动脉粥样硬化和再狭窄）。
T36717	RWJ-56110 dihydrochloride
	RWJ-56110 dihydrochloride is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4. RWJ-56110 dihydrochloride inhibits the aggregation of human platelets induced by both SFLLRN-NH2 (IC50=0.16 μM) and thrombin (IC50=0.34 μM), quite selective relative to U46619 . RWJ-56110 dihydrochloride blocks angiogenesis and blocks the formation of new vessels in vivo. RWJ-56110 dihydrochloride induces cell ap...
T74266	Protease-Activated Receptor-1 antagonist 2
	Protease-Activated Receptor-1 antagonist 2 是一种选择性蛋白酶激活受体-1 (PAR-1) 拮抗剂，口服活性，IC50值为7 nM。该化合物具有优良的药代动力学特性，适用于心血管疾病 (CVD) 如动脉粥样硬化和再狭窄的研究。
T4186	AC-264613 AC264613	Protease-activated Receptor	GPCR/G Protein
	AC-264613 是一种选择性蛋白酶激活受体 (PAR-2) 激动剂，pEC50为 7.5。

化合物

PAR-2 Activating Peptide acetate

Cat.No: TP1046L

Synonym: SLIGRL-NH2 acetate,PAR-2 Activating Peptide acetate(171436-38-7 free base),Protease-Activated Receptor-2 Activating Peptide acetate

Target: Protease-activated Receptor

Cat.No: T8917

Synonym: IUN76750,8-(叔丁基)-6-氯咪唑并[1,2-B]吡啶-2-羧酸甲酯

Target: Protease-activated Receptor

Cat.No: TP1046

Synonym: Protease-Activated Receptor-2 Activating Peptide

Target: Protease-activated Receptor

Cat.No: T1893

Synonym: ML 161

Target: Protease-activated Receptor

prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens]

Cat.No: T23189

Target: Others

PAR2 (1-6) (mouse, rat)

Cat.No: T36531

Synonym: PAR2 (1-6) (mouse, rat)

Protease-Activated Receptor-2, amide

Cat.No: T7513

Synonym: 蛋白酶活化的受体-2，酰胺,SLIGKV-NH2,H-丝氨酰亮氨酰异亮氨酰甘氨酰赖氨酰缬氨酰NH2

Target: Protease-activated Receptor

PAR2 (1-6) amide (human) (trifluoroacetate salt)

Cat.No: T35955

Synonym: PAR2 (1-6) amide (human) (trifluoroacetate salt)

PAR-2 (1-6) (human)

Cat.No: T76650

Cat.No: T28281

Synonym: OXSI 2,Syk Inhibitor

Target: Syk

Cat.No: T7573

Synonym: TFLLR-NH2(2TFA)

Target: Protease-activated Receptor

PAR-4 Agonist Peptide, amide TFA

Cat.No: TP1065

Synonym: PAR-4-AP (TFA),AY-NH2 (TFA)

Target: Protease-activated Receptor

Protease-Activated Receptor-1, PAR-1 Agonist acetate

Cat.No: T38836L

Target: Protease-activated Receptor

LRGILS-NH2 acetate

Cat.No: T22933L

Target: Protease-activated Receptor

Cat.No: T27267

Synonym: ENMD-1068 HCl,ENMD 1068,ENMD-1068,ENMD1068,ENMD-1068 hydrochloride

Target: Protease-activated Receptor

Acetyl Hexapeptide-49 Acetate

Cat.No: TP2494

Synonym: Acetyl Hexapeptide-49 Acetate(1459205-54-9 Free base)

Target: Others

Protease-Activated Receptor-3 (PAR-3) (1-6), human

Cat.No: T36286

Protease-Activated Receptor-1, PAR-1 Agonist TFA

Cat.No: T36288

PAR-4 Agonist Peptide, amide

Cat.No: T7623

Synonym: AY-NH2,PAR-4 Agonist Peptide, amide(2TFA),PAR-4-AP

Target: Protease-activated Receptor

Cat.No: T75902

Synonym: Protease-Activated Receptor-2 Activating Peptide TFA

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2

Cat.No: T80240

Cat.No: T36293

Parstatin(mouse) TFA

Cat.No: T75872

Parstatin(human) TFA

Cat.No: T75873

Cat.No: T27708

Protease-Activated Receptor-1 antagonist 2

Cat.No: T64285

RWJ-56110 dihydrochloride

Cat.No: T36717

Protease-Activated Receptor-1 antagonist 2

Cat.No: T74266

Cat.No: T4186

Synonym: AC264613

Target: Protease-activated Receptor

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