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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T73477 | SHP844 | ||
SHP844为一SHP2抑制剂,IC50值为18.9 µM。SHP2为蛋白酪氨酸磷酸酶(PTP),调控酪氨酸磷酸化水平,影响细胞增殖、分化及存活。 | |||
T35525 |
PI3-Kinase α Inhibitor 2
PI3-Kinase α Inhibitor 2 |
||
Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of the 3' hydroxyl position of PIs to produce the second messengers PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3. PI3Kα, β, and δ are class 1A enzymes composed of p110 and p85 subunits, whereas PI3Kγ is a class 1B PI3K composed of a p110 catalytic subunit and a p101 or p84 regulatory subunit. PI3Kα inhibitor 2 is a selective inhibitor of PI3Kα with IC50 values of 2, 16, 660, and 220 nM for the α, β, γ, and 2Cβ isoforms, respectively. It... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02632 |
SIRP alpha Protein, Mouse, Recombinant (His)
SHP-1,CD172a,SIRP,SHPS-1,SIRP α,Ptpns1,signal-regulatory pro... |
Mouse | HEK293 Cells |
SIRP alpha Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.4 kDa and the accession number is BAA20376.1. | |||
TMPY-06051 |
SIRP alpha Protein, Human, Recombinant (hFc)
signal-regulatory protein alpha,SIRP alpha,PTPNS1,P84 |
Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64 kDa and the accession number is P78324-1. | |||
TMPY-01573 |
SIRP alpha Protein, Human, Recombinant (G75A, His)
PTPNS1,signal-regulatory protein alpha,SIRP,MYD-1,CD172A,MFR... |
Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (G75A, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39 kDa and the accession number is P78324-1. | |||
TMPY-06052 |
SIRP alpha V2 Protein, Human, Recombinant (His)
SIRP α,P84,PTPNS1,signal-regulatory protein α,signa... |
Human | HEK293 Cells |
SIRP alpha V2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.6 kDa and the accession number is AAH38510.1. | |||
TMPK-01356 |
SIRP alpha V4 Protein, Human, Recombinant (His & Avi)
BIT,SIRP α V4,MFR,SHPS1,SIRPA,SIRP α,P84,MYD1,MYD-1... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi... | |||
TMPK-01358 |
SIRP alpha V6 Protein, Human, Recombinant (His & Avi)
P84,SIRPA,SIRP alpha,SHPS-1,MFR,BIT,MYD1,SIRP α V6,... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V6 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi... | |||
TMPK-01364 |
SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated
SIRP α,MFR,SHPS1,SIRPA,BIT,SHPS-1,MYD-1,SIRP alpha,P84 |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPK-01357 |
SIRP alpha V5 Protein, Human, Recombinant (His & Avi)
MFR,PTPNS1,P84,BIT,MYD-1,MYD1,SHPS-1,SIRPA,SIRP α,S... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal. | |||
TMPK-00626 |
SIRP alpha V8 Protein, Human, Recombinant (His & Avi)
SIRP alpha,P84,MYD1,MYD-1,SHPS1,BIT,SIRP α V8,PTPNS... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V8 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi... | |||
TMPK-00307 |
SIRP alpha Protein, Human, Recombinant (aa 31-370, hFc & Avi), Biotinylated
SHPS1,SIRP alpha,SHPS-1,SIRPA,MYD-1,BIT,CD172a,MYD1,MFR,PTPN... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha Protein, Human, Recombinant (aa 31-370, hFc & Avi), Biotinylated is expressed in HEK293 mam... | |||
TMPK-00628 |
SIRP alpha V3 Protein, Human, Recombinant (His & Avi), Biotinylated
P84,SIRP alpha,MYD-1,SIRP α,SHPS-1,SIRPA,SHPS1,MFR,... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPK-01363 |
SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated
SIRP alpha,MFR,PTPNS1,SIRP α V5,P84,SHPS-1,BIT,CD17... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPY-06054 |
SIRP alpha V8 Protein, Human, Recombinant (His)
SIRP α,BIT,SIRP,PTPNS1,P84,SIRP α(SIRP αV8),CD172A,... |
Human | HEK293 Cells |
SIRP alpha V8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.6 kDa and the accession number is AAH38510.1. | |||
TMPK-00625 |
SIRP alpha V3 Protein, Human, Recombinant (His & Avi)
P84,SIRP alpha,CD172a,MFR,MYD-1,PTPNS1,SIRPA,SHPS1,... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi... | |||
TMPK-01362 |
SIRP alpha V4 Protein, Human, Recombinant (His & Avi), Biotinylated
MYD1,SIRP α V4,PTPNS1,BIT,SHPS1,SIRP alpha,SHPS-1,SIRP α,MFR... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPJ-00961 |
STAT1 Protein, Human, Recombinant
Transcription Factor ISGF-3 Components p91/p84,STAT... |
Human | E. coli |
Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated, STAT1 can form a homodimer termed IFN-gamma-activated factor (GAF), migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. STAT1 functions as signal transducer and transcription activator that mediates cellul... | |||
TMPK-00627 |
SIRP alpha V8 Protein, Human, Recombinant (His & Avi), Biotinylated
P84,MFR,MYD1,SHPS-1,SIRP alpha,SIRP α,SIRPα,MYD-1,P... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V8 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPY-02636 |
SIRP alpha Protein, Mouse, Recombinant (hFc)
CD172a,AI835480,SIRP,signal-regulatory protein α,signal-regu... |
Mouse | HEK293 Cells |
SIRP alpha Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64.9 kDa and the accession number is BAA20376.1. | |||
TMPY-06284 |
SIRP alpha Protein, Human, Recombinant (hFc & Avi), Biotinylated
SIRP,P84,signal-regulatory protein α,BIT,SHPS1,CD17... |
Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 65.85 kDa and the accession number is P78324-1. | |||
TMPY-05126 |
SIRP alpha Protein, Human, Recombinant (G75A, His), Biotinylated
SIRP α,SIRP alpha,MYD-1,BIT,MFR,SHPS1,CD172A,P84,SI... |
Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (G75A, His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.8 kDa and the accession number is P78324-1. | |||
TMPK-00609 |
SIRP alpha V2 Protein, Human, Recombinant (His & Avi), Biotinylated
P84,PTPNS1,SIRPαV2,SIRPalpha V2,CD172a,MYD1,MYD-1,S... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPK-00611 |
SIRP alpha V2 Protein, Human, Recombinant (aa 31-369, His)
MYD-1,SHPS1,MFR,PTPNS1,CD172a,SIRPA,SIRP α V2/CD172a,SHPS-1,... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V2 Protein, Human, Recombinant (aa 31-369, His) is expressed in HEK293 mammalian cells with... | |||
TMPY-05263 |
SIRP alpha Protein, Human, Recombinant (mFc)
signal-regulatory protein alpha,SIRP alpha,SHPS1,MYD-1,PTPNS... |
Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 63.7 kDa and the accession number is P78324-1. | |||
TMPK-00610 |
SIRP alpha V2 Protein, Human, Recombinant (hFc)
PTPNS1,MYD-1,MFR,SHPS1,SIRPalpha2,SIRPα2,SIRPA,SIRP α V2/CD1... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag.... | |||
TMPY-06053 |
SIRP alpha V2 Protein, Human, Recombinant (mFc)
MFR,CD172A,P84,PTPNS1,SIRP alpha,SIRP α(SIRP αV2),s... |
Human | HEK293 Cells |
SIRP alpha V2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 63.5 kDa and the accession number is AAH38510.1. | |||
TMPY-06248 |
SIRP alpha V2 Protein, Human, Recombinant (His), Biotinylated
SIRP α(SIRP αV2),BIT,signal-regulatory protein alpha,signal-... |
Human | HEK293 Cells |
SIRP alpha V2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.6 kDa and the accession number is AAH38510.1. | |||
TMPY-06055 |
SIRP alpha V8 Protein, Human, Recombinant (mFc)
signal-regulatory protein α,signal-regulatory protein alpha,... |
Human | HEK293 Cells |
SIRP alpha V8 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 63.6 kDa and the accession number is AAH38510.1. |