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39

抑制剂 & 化合物

3

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T0902	Ofloxacin DL8280,菲宁达,Hoe-280,氧氟沙星,Floxin,Tarivid,Oxaldin	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Ofloxacin (Oxaldin) 是可抑制细菌DNA 旋转酶的一种氟喹诺酮类抗生素。
T17307	(R)-Ofloxacin DR3354,D-Ofloxacin,DR-3354,DR 3354,(R)-氧氟沙星,(R)-(+)-Ofloxacin,(+)-Ofloxacin	Others	Others
	(R)-Ofloxacin is a R-isomer of Ofloxacin, an antibiotic used to treat a number of bacterial infections.
T36031	Desmethyl Ofloxacin (hydrochloride)
	Desmethyl ofloxacin is a metabolite of the fluoroquinolone antibiotic ofloxacin .1 1.Sudo, K., Okazaki, O., Tsumura, M., et al.Isolation and identification of metabolites of ofloxacin in rats, dogs and monkeysXenobiotica16(8)725-732(1986)
T71982	Ofloxacin HCl
	Ofloxacin HCl is a synthetic fluoroquinolone ( FLUOROQUINOLONES) antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
T64502	(S)-Decarboxyl ofloxacin
	(S)-Decarboxyl ofloxacin 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64502。
T71310	DS 4574
	DS 4574 is a peptidoleukotriene receptor antagonist used in treatment of hypersensitivity.
T1451	Levofloxacin hydrate 左氧氟沙星半水合物,Levaquin hydrate,Cravit hydrate,Quixin hydrate,Levofloxacin Hemihydrate,Tavanic hydrate,Iquix hydrate	DNA gyrase; Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Levofloxacin hydrate (Cravit hydrate) 是抗生素化合物，抑制细菌DNA 旋转酶活性。
T8747	Levofloxacin hydrochloride	DNA gyrase; Topoisomerase	DNA Damage/DNA Repair
	Levofloxacin hydrochloride 是一种广谱的第三代氟喹诺酮类抗生素，是氧氟沙星的光学活性 L-异构体，具有抗菌活性。左氧氟沙星通过细菌细胞壁扩散并通过抑制 DNA 促旋酶（细菌拓扑异构酶 II）起作用，这是一种 DNA 复制、RNA 转录和细菌 DNA 修复所需的酶。 DNA 促旋酶活性的抑制导致细菌细胞生长受阻。
T3117	Marbofloxacin 马波沙星,Marbofloxacine,Zeniquin,Marbocyl	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Marbofloxacin (Zeniquin) 是一种具有口服活性的氟喹诺酮类广谱抗菌剂。它可研究革兰氏阳性和革兰氏阴性细菌以及支原体引起的感染。
T7865	Danofloxacin 达氟沙星,达诺沙星,Danofloxacino,Danofloxacin free base,Danofloxacine	Others; DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Danofloxacin (Danofloxacin free base) free base 是一种具有口服活性第三代氟喹诺酮抗菌剂，对大多数革兰氏阴性和革兰氏阳性细菌，支原体和衣原体物种具有广谱的活性，并通过抑制细菌的 DNA 回转酶发挥抗菌作用。它可用于牛，猪和鸡呼吸道疾病的研究。
T1617	Enrofloxacin 恩诺沙星,BAY-Vp2674,PD160788	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Enrofloxacin (BAY-Vp2674) 是一种作用于支原体的抗生素，MIC90为 0.312 μg/mL。
T0250	Ciprofloxacin monohydrochloride Bay-09867 (hydrochloride),Ciprofloxacin HCl,盐酸环丙沙星,环丙沙星盐酸盐,Ciprofloxacin hydrochloride	DNA gyrase; Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Ciprofloxacin monohydrochloride (Bay-09867 hydrochloride) 是一种高抗菌活性的氟喹诺酮类抗生素。
T8606	n-acetylciprofloxacin N-乙酰基环丙沙星,3-Quinolinecarboxylic acid, 7-(4-acetyl-1-piperazinyl)-1-cyclopropyl-6-fluoro-1	Others	Others
	n-acetylciprofloxacin (3-Quinolinecarboxylic acid, 7-(4-acetyl-1-piperazinyl)-1-cyclopropyl-6-fluoro-1) 是 H37Rv 的抑制剂。
T1733	Ciprofloxacin EP IMpurity A Q-Acid,Fluoroquinolonic Acid,环丙羧酸,Ciprofloxacin Impurity A	Antibiotic	Microbiology/Virology
	Ciprofloxacin EP IMpurity A (Fluoroquinolonic Acid) 是一种抗生素和抗菌剂。
T0116	Balofloxacin	DNA gyrase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Balofloxacin 是一种具有口服活性的氟喹诺酮类抗生素，可通过干扰 DNA 促旋酶来抑制细菌 DNA 的合成，对革兰氏阴性，革兰氏阳性和厌氧菌具有广谱抗菌活性。它可研究呼吸道，肠道和泌尿道感染。
T1640	Ciprofloxacin Ciproxan,环丙沙星,Ciprobay,Bay o 9867,Bay-09867	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Ciprofloxacin (Bay-09867) 是一种有高抗菌活性的氟喹诺酮类抗生素。
T11007L	Levofloxacin Hydrochloride Impurity A Levofloxacin Hydrochloride Impurity A(117707-40-1 Free base),左氧氟沙星杂质A(盐酸盐)	Antibacterial	Microbiology/Virology
	Levofloxacin Hydrochloride Impurity A 是一种喹诺酮类药物，具有广谱抗菌作用。
T38003	Levofloxacin N-oxide	Others	Others
	Levofloxacin N-oxide 是从左氧氟沙星中分离出来的杂质。
T1451L	Levofloxacin sodium
	Levofloxacin sodium is a synthetic fluoroquinolones antibacterial. It inhibits the supercoiling activity of bacterial DNA gyrase, so that halting DNA replication.
T81412	Pradofloxacin
	Pradofloxacin是一种第三代的氟喹诺酮类抗菌化合物。
T10420	Avarofloxacin JNJ-Q2	Others	Others
	Avarofloxacin (JNJ-Q2) is a broad-spectrum fluoroquinolone antibacterial drug being developed for the treatment of acute bacterial skin and community-acquired pneumonia and skin structure infections.
T22265	Balofloxacin Dihydrate Neuroquinoron,巴洛沙星/1-环丙基-7-(3-甲氨基-1-哌啶基)-8-甲氧基-6-氟-1,4-二氢-4-氧代-3-喹啉羧酸	Others	Others
	Balofloxacin is a fluoroquinolone antibiotic with oral activity.
T66299	Ciprofloxacin lactate
	Ciprofloxacin lactate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66299，CAS号为 97867-33-9。
T75290	Enrofloxacin monohydrochloride
	Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) 为一种针对Mycoplasma bovis具有高效抗菌作用的抗生素，MIC90值为0.312 μg/mL。此外，Enrofloxacin monohydrochloride 亦展现出对牛痘病毒的抗病毒活性。
T36030	Desethylene Ciprofloxacin (hydrochloride)
	Desethylene ciprofloxacin is a major metabolite of ciprofloxacin . It is also a degradation product of ciprofloxacin that can be created through advanced oxygenation processes as a potential way to remove ciprofloxacin from wastewater. It is also created during degradation of ciprofloxacin by chlorination.
T13406	Zabofloxacin DW-224a Free base	Others	Others
	Zabofloxacin is a potent and seletive bacterial type II and IV topoisomerases inhibitor, and has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia.
T67345	Enrofloxacin hcl
	Enrofloxacin hydrochloride is an effective antibiotic with an MIC90 of 0.312 μg/mL for Mycoplasma bovis.
T26638	Antofloxacin Hydrochloride (S)-Antofloxacin hydrochloride,Antofloxacin HCl
	Antofloxacin Hydrochloride, a fluoroquinolone antimicrobial, is used to treat acute exacerbation of chronic bronchitis (AECB), acute pyelonephritis(AP), acute cystitis and multiple folliculitis.
T11007	Desmethyl Levofloxacin	Others	Others
	Desmethyl Levofloxacin is a metabolite of levofloxacin. Levofloxacin is a synthetic fluoroquinolone drug, an antibacterial agent that can inhibit the super-coiling activity of bacterial DNA gyrase and prevent DNA replication.
T13406L	Zabofloxacin hydrochloride DW-224a	Raf	MAPK
	Zabofloxacin hydrochloride is a potent and seletive bacterial type II and IV topoisomerases inhibitor, has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia.
T72175	Marbofloxacin hydrochloride 盐酸马波沙星
	Marbofloxacin hydrochloride，一种第三代具口服活性的氟喹诺酮类抗菌剂，展现广谱杀菌效能及优良疗效。适用于探究由革兰氏阳性与革兰氏阴性细菌及支原体所引发的感染。
T71984	Enrofloxacin-d5
	Enrofloxacin-d5 is intended for use as an internal standard for the quantification of enrofloxacin by GC- or LC-MS. Enrofloxacin is a fluoroquinolone antibiotic. It is active against panels of Campylobacter, E. coli, and Salmonella isolates (mean MIC50s = 0.06, 0.5, and 0.03 µg/ml, respectively). It is also active against equine isolates of L. intracellularis (MICs = 0.125-0.5 µg/ml). Enrofloxacin inhibits bacterial DNA gyrase. In vivo, enrofloxacin (10 mg/kg) increases survival in a mouse model...
T23703	Alatrofloxacin
	Alatrofloxacin is a prodrug of trovafloxacin.
T38581	Antofloxacin
	Antofloxacin is a well-tolerated, orally active, and broad-spectrum 8-amino-fluoroquinolone compound that exhibits potent antibacterial properties. It demonstrates superior activity against gyrA mutation-positive Helicobacter pylori strains, particularly in strains with mutations in the Asn87 position, when compared to levofloxacin. Additionally, Antofloxacin acts as a weak but reversible inhibitor of CYP1A2 and is clinically used to treat infections caused by various bacterial species.
T29829	Alatrofloxacin Mesylate UNII-2IXX802851,CP 116517,Alatrofloxacin mesylate (USAN),CP 116,517
	Alatrofloxacin Mesylate is the parental prodrug of broad-spectrum antibiotic trovafloxacin.
T67987	ecenofloxacin
	Ecenofloxacin 是一种氟喹诺酮类抗菌药物，对革兰氏阳性、革兰氏阴性和厌氧生物具有有效的抗菌活性。
T30684	Cadrofloxacin CS-940,CS 940,Cadrofloxacin hydrochloride,Caderofloxacin,CS940
	Cadrofloxacin (Caderofloxacin, CS-940) is a novel fluoroquinolone antimicrobial agent.
T13346L	WQ3810 TFA WQ3810 TFA(888032-58-4 Free base),KPI-10 TFA	Antifungal	Microbiology/Virology
	WQ3810 TFA 是一种可口服的氟喹诺酮，具有抗菌活性，对结核分枝杆菌有抑制作用，抑制氧氟沙星耐药麻风分枝杆菌的 DNA 旋转酶活性。
T75296	Pazufloxacin
	Pazufloxacin (T-3761)是氟喹诺酮类广谱抗生素。

化合物

Cat.No: T0902

Synonym: DL8280,菲宁达,Hoe-280,氧氟沙星,Floxin,Tarivid,Oxaldin

Target: Topoisomerase, Antibacterial, Antibiotic

(R)-Ofloxacin

Cat.No: T17307

Synonym: DR3354,D-Ofloxacin,DR-3354,DR 3354,(R)-氧氟沙星,(R)-(+)-Ofloxacin,(+)-Ofloxacin

Target: Others

Desmethyl Ofloxacin (hydrochloride)

Cat.No: T36031

Ofloxacin HCl

Cat.No: T71982

(S)-Decarboxyl ofloxacin

Cat.No: T64502

Cat.No: T71310

Levofloxacin hydrate

Cat.No: T1451

Synonym: 左氧氟沙星半水合物,Levaquin hydrate,Cravit hydrate,Quixin hydrate,Levofloxacin Hemihydrate,Tavanic hydrate,Iquix hydrate

Target: DNA gyrase, Topoisomerase, Antibacterial, Antibiotic

Levofloxacin hydrochloride

Cat.No: T8747

Target: DNA gyrase, Topoisomerase

Cat.No: T3117

Synonym: 马波沙星,Marbofloxacine,Zeniquin,Marbocyl

Target: Topoisomerase, Antibacterial, Antibiotic

Cat.No: T7865

Synonym: 达氟沙星,达诺沙星,Danofloxacino,Danofloxacin free base,Danofloxacine

Target: Others, DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T1617

Synonym: 恩诺沙星,BAY-Vp2674,PD160788

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Ciprofloxacin monohydrochloride

Cat.No: T0250

Synonym: Bay-09867 (hydrochloride),Ciprofloxacin HCl,盐酸环丙沙星,环丙沙星盐酸盐,Ciprofloxacin hydrochloride

Target: DNA gyrase, Topoisomerase, Antibacterial, Antibiotic

n-acetylciprofloxacin

Cat.No: T8606

Synonym: N-乙酰基环丙沙星,3-Quinolinecarboxylic acid, 7-(4-acetyl-1-piperazinyl)-1-cyclopropyl-6-fluoro-1

Target: Others

Ciprofloxacin EP IMpurity A

Cat.No: T1733

Synonym: Q-Acid,Fluoroquinolonic Acid,环丙羧酸,Ciprofloxacin Impurity A

Target: Antibiotic

Cat.No: T0116

Target: DNA gyrase, Antibacterial, Antibiotic

Cat.No: T1640

Synonym: Ciproxan,环丙沙星,Ciprobay,Bay o 9867,Bay-09867

Target: Topoisomerase, Antibacterial, Antibiotic

Levofloxacin Hydrochloride Impurity A

Cat.No: T11007L

Synonym: Levofloxacin Hydrochloride Impurity A(117707-40-1 Free base),左氧氟沙星杂质A(盐酸盐)

Target: Antibacterial

Levofloxacin N-oxide

Cat.No: T38003

Target: Others

Levofloxacin sodium

Cat.No: T1451L

Cat.No: T81412

Cat.No: T10420

Synonym: JNJ-Q2

Target: Others

Balofloxacin Dihydrate

Cat.No: T22265

Synonym: Neuroquinoron,巴洛沙星/1-环丙基-7-(3-甲氨基-1-哌啶基)-8-甲氧基-6-氟-1,4-二氢-4-氧代-3-喹啉羧酸

Target: Others

Ciprofloxacin lactate

Cat.No: T66299

Enrofloxacin monohydrochloride

Cat.No: T75290

Desethylene Ciprofloxacin (hydrochloride)

Cat.No: T36030

Cat.No: T13406

Synonym: DW-224a Free base

Target: Others

Enrofloxacin hcl

Cat.No: T67345

Antofloxacin Hydrochloride

Cat.No: T26638

Synonym: (S)-Antofloxacin hydrochloride,Antofloxacin HCl

Desmethyl Levofloxacin

Cat.No: T11007

Target: Others

Zabofloxacin hydrochloride

Cat.No: T13406L

Synonym: DW-224a

Target: Raf

Marbofloxacin hydrochloride

Cat.No: T72175

Synonym: 盐酸马波沙星

Enrofloxacin-d5

Cat.No: T71984

Cat.No: T23703

Cat.No: T38581

Alatrofloxacin Mesylate

Cat.No: T29829

Synonym: UNII-2IXX802851,CP 116517,Alatrofloxacin mesylate (USAN),CP 116,517

Cat.No: T67987

Cat.No: T30684

Synonym: CS-940,CS 940,Cadrofloxacin hydrochloride,Caderofloxacin,CS940

Cat.No: T13346L

Synonym: WQ3810 TFA(888032-58-4 Free base),KPI-10 TFA

Target: Antifungal

Cat.No: T75296

Cat. No.	Product Name	Target	Signaling Pathways
T6567	Levofloxacin Levaquin,Cravit,Tavanic,Fluoroquinolone,左氧氟沙星,(-)-Ofloxacin	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Levofloxacin (Fluoroquinolone) 是合成的氟喹诺酮类抗生素，有抑制细菌DNA 旋转酶的超螺旋活性的作用，能阻止DNA 复制。
T8130	Ciprofloxacin hydrochloride monohydrate Oftacilox,Ciprofloxacin hydrochloride hydrate,Bay-09867 hydrochloride monohydrate,环丙沙星盐酸盐一水合物,Ceprimax,盐酸环丙沙星(一水物),Ciloxan	Antibacterial; Antibiotic	Microbiology/Virology
	Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) 是一种具有高效抗菌活性的氟喹诺酮类抗生素。
T1276	Danofloxacin mesylate 甲磺酸达氟沙星,CP 76136-27	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Danofloxacin mesylate (CP 76136-27) 是一种兽医用氟喹诺酮类抗菌素。

天然产物

Cat.No: T6567

Synonym: Levaquin,Cravit,Tavanic,Fluoroquinolone,左氧氟沙星,(-)-Ofloxacin

Target: Topoisomerase, Antibacterial, Antibiotic

Ciprofloxacin hydrochloride monohydrate

Cat.No: T8130

Synonym: Oftacilox,Ciprofloxacin hydrochloride hydrate,Bay-09867 hydrochloride monohydrate,环丙沙星盐酸盐一水合物,Ceprimax,盐酸环丙沙星(一水物),Ciloxan

Target: Antibacterial, Antibiotic

Danofloxacin mesylate

Cat.No: T1276

Synonym: 甲磺酸达氟沙星,CP 76136-27

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

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