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Cat. No. | Product Name | Target | Signaling Pathways |
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T65288 |
Methacrylic anhydride
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Others | Others |
Methacrylic anhydride 是一种可聚合 1,6- 二烯烃的化合物,可以通过自由基引发形成可溶的环己烷聚合物。Methacrylic anhydride 可以通过乙烯基自发聚合, 2-6- 二叔丁基 4- 甲基苯酚对此有抑制作用。Methacrylic anhydride 可用于研究新型水凝胶。 | |||
T4615 |
Balsalazide sodium hydrate
巴柳氮钠水合物,Balsalazide disodium dihydrate,巴柳氮钠,Balsalazide disodium salt dihydrate,Balsalazide disodium |
STAT; Interleukin | Immunology/Inflammation; JAK/STAT signaling; Stem Cells |
Balsalazide sodium hydrate (Balsalazide disodium) 可通过调节IL-6/STAT3通路起抑癌作用,可用于治疗炎症性肠病。 | |||
T38192 |
Unifiram
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Others | Others |
Unifiram 是一种认知增强剂。 Unifiram 诱导大鼠海马 CA1 区场兴奋性突触后电位 (fEPSP) 幅度的持久增加 (EC50= 27 nM) 并增加大鼠大脑皮层中乙酰胆碱 (ACh) 的释放。 | |||
T62486 | VIM-2-IN-1 | ||
VIM-2-IN-1 (compound 1dj) 是一种 β-内酰胺酶 (β-lactamase) 抑制剂,具有抗菌作用。VIM-2-IN-1 能够作用于 Verona 整合子编码的金属-β-内酰胺酶 (VIM-2) (IC50: 23 μM)、德国亚胺培内酶-1 (GIM-1) (IC50: 48 μM) 和新德里金属 (NDM-1) (IC50: 231 μM)。 | |||
T74622 |
Antibacterial agent 109
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Antibacterial agent 109 (Compound C-2) 是一种有效的抗细菌 (antibacterial) 剂,对革兰氏阳性和革兰氏阴性细菌均有效,且无诱变作用。Antibacterial agent 109 通过阻断新肽链的延伸抑制蛋白质合成。 | |||
T60286 | DHFR-IN-2 | ||
DHFR-IN-2 (化合物 4e) 是一种有效且非竞争性的MtDHFR 抑制剂,其IC50值为 7 μM。来自结核分枝杆菌 (MtDHFR) 的二氢叶酸还原酶具有很高的未开发潜力,可以成为抗结核病 (TB) 新药的靶标,因为它对病原体存活很重要。DHFR-IN-2可用于结核病(TB)研究。 | |||
T71230 |
VMY-1-103
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VMY-1-103 is a potent CDK inhibitor, is also a novel dansylated analog of purvalanol B, was shown to inhibit cell cycle progression and proliferation in prostate and breast cancer cells more effectively than purvalanol B. VMY-1-103 , but not purvalanol B, significantly decreased the proportion of cells in S phase and increased the proportion of cells in G(2)/M. VMY-1-103 increased the sub G(1) fraction of apoptotic cells, induced PARP and caspase-3 cleavage and increased the levels of the Death ... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN6550 |
New compound 2
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New compound 2 可用于生命科学领域的相关研究,其产品编号为 TN6550。 | |||
TWS2045 |
Bruceine D
鸦胆子素D,鸦胆子苦素D |
Apoptosis; Antiviral; Gamma-secretase; Parasite | Apoptosis; Immunology/Inflammation; Microbiology/Virology; Neuroscience; Proteases/Proteasome; Stem Cells |
Bruceine D 是Notch 抑制剂,有抗癌活性,诱导几种人癌细胞调亡。它是一种有效的植物性昆虫拒食剂,有显著的系统特性和抑制害虫生长的作用。它具有较强的驱虫活性,抑制D. intermedius 的 EC50值为 0.57 mg/L。 | |||
T4S21320 |
ISOGINKGETIN
异银杏素,4',4'''-Dimethylamentoflavone,异银杏双黄酮 |
MMP; Others | Others; Proteases/Proteasome |
ISOGINKGETIN (4',4'''-Dimethylamentoflavone) 是一种MMP9抑制剂,也是一种Pre-mRNA Splicing 抑制剂。 | |||
T37690 |
Phenylpyropene A
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Phenylpyropene A is a fungal metabolite originally isolated from P. griseofulvum that has enzyme inhibitory and insecticidal activities.1,2,3 It inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 0.8 μM).1 Phenylpyropene A inhibits diacylglycerol acyltransferase (DGAT) in rat liver microsomes (IC50 = 78.7 μM). It induces mortality in 100% of M. persicae when used at a concentration of 5 ppm.3 |1. Kwon, O.E., Rho, M.C., Song, H.Y., et al. Phenylpyropene A and B, new inhibitors of ... |