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Cat. No. Product Name Target Signaling Pathways
T1582 Naproxen

萘普生,(S)-Naproxen

COX; Autophagy Autophagy; Immunology/Inflammation; Neuroscience
Naproxen ((S)-Naproxen) 是COX-1和COX-2的抑制剂,在细胞试验中IC50值分别为8.72 和5.15 μM。它是丙酸衍生物和非甾体抗炎药,具有抗炎、解热和镇痛活性。
T0855 (R)-Naproxen

COX Immunology/Inflammation; Neuroscience
(R)-Naproxen 是一种抗炎剂,具有解热和镇痛作用。酸及其钠盐都用于治疗急性痛风或痛经、肌肉骨骼疾病、类风湿性关节炎和其他风湿病。
T1582L Naproxen sodium

Miranax,Anaprox,RS-3650,Naprelan,萘普生钠

COX; Autophagy Autophagy; Immunology/Inflammation; Neuroscience
Naproxen sodium (Anaprox) 是COX 抑制剂,用于 COX-1 和 COX-2,具有镇痛和解热特性。
T20667 Racemic Naproxen

DL-Naproxen,DL Naproxen

Racemic Naproxen is a biochemical substance.
T69267 Naproxen glucuronide

Naproxen glucuronide is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same class as ibuprofen) that relieves pain, fever, swelling, and stiffness. It is a nonselective COX inhibitor.
T69474 Naproxen ethyl ester

Naproxen ethyl ester is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same class as ibuprofen) that relieves pain, fever, swelling, and stiffness. It is a non-selective COX inhibitor.
T16272 Naproxen etemesil

LT-NS 001,MX 1094

PDE Metabolism
Naproxen is a COX-1 and COX-2 inhibitor (IC50s: 8.72 and 5.15 μM, respectively in cell assay). Naproxen etemesil is a lipophilic and non-acidic prodrug of naproxen. It is hydrolyzed to pharmacologically active Naproxen once absorbed.
T0556 6-Methoxy-2-naphthoic acid

Naproxen impurity O,6-Methoxy-2-naphthalenecarboxylic acid,6-甲氧基-2-萘甲酸

NMDAR; iGluR Membrane transporter/Ion channel; Neuroscience
6-Methoxy-2-naphthoic acid (6-Methoxy-2-naphthalenecarboxylic acid) 是NMDA 受体调节剂。
T33595 Naproxcinod

AZD3582,Nitronaproxen,AZD-3582,Naproxen-N-butyl nitrate,HCT3012,AZD 3582

Naproxcinod, a nitric oxide-releasing NSAID derivative, significantly improved skeletal muscle strength and fatigue resistance in sedentary and exercise mice, reducing inflammatory infiltration and fibrotic deposition in the myocardium and diaphragm. In a
T7662 α-Demethylnaproxen

COX Immunology/Inflammation; Neuroscience
α-Demethylnaproxen 是一种 COX 的竞争性抑制剂(羊 COX-1 和 -2 的 Ki 值分别为 21 和 19 μM)。
T0637 2-Acetyl-6-methoxynaphthalene

Others Others
2-Acetyl-6-methoxynaphthalene 是naphthalene tome 和naproxen 的关键中间体,用于合成非甾体抗炎镇痛药。
T1867 Otenaproxesul

ATB 346

Apoptosis; COX Apoptosis; Immunology/Inflammation; Neuroscience
Otenaproxesul (ATB 346) 是一种具有口服活性的非甾体抗炎药,可抑制环氧合酶-1 和 2,具有抗炎生物活性,可用于缓解疼痛的研究。
T1350 4-Butoxyphenol

4-正丁氧基苯酚,P-Butoxyphenol

Others Others
4-Butoxyphenol (P-Butoxyphenol) 是一种在科学和工业领域有广泛应用的酚类化合物。它经常用于合成其他化合物,如4-丁氧基苯乙酸和4-丁氧基苯乙腈;还用于合成药物,如布洛芬和萘普生。
T37176 Edoxaban impurity 6

Edoxaban impurity 6 is an impurity of Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention[1][2]. [1]. Furugohri T, et al. DU-176b, a potent and orally active factor Xa inhibitor: in vitro and in vivo pharmacological profiles. J Thromb Haemost. 2008 Sep;6(9):1542-9.[2]. Mendell J, Lee F, Chen S, The Effe...

化合物

Naproxen
Cat.No: T1582
Synonym: 萘普生,(S)-Naproxen
Target: COX, Autophagy
(R)-Naproxen
Cat.No: T0855
Synonym:
Target: COX
Naproxen sodium
Cat.No: T1582L
Synonym: Miranax,Anaprox,RS-3650,Naprelan,萘普生钠
Target: COX, Autophagy
Racemic Naproxen
Cat.No: T20667
Synonym: DL-Naproxen,DL Naproxen
Target:
Naproxen glucuronide
Cat.No: T69267
Synonym:
Target:
Naproxen ethyl ester
Cat.No: T69474
Synonym:
Target:
Naproxen etemesil
Cat.No: T16272
Synonym: LT-NS 001,MX 1094
Target: PDE
6-Methoxy-2-naphthoic acid
Cat.No: T0556
Synonym: Naproxen impurity O,6-Methoxy-2-naphthalenecarboxylic acid,6-甲氧基-2-萘甲酸
Target: NMDAR, iGluR
Naproxcinod
Cat.No: T33595
Synonym: AZD3582,Nitronaproxen,AZD-3582,Naproxen-N-butyl nitrate,HCT3012,AZD 3582
Target:
α-Demethylnaproxen
Cat.No: T7662
Synonym:
Target: COX
2-Acetyl-6-methoxynaphthalene
Cat.No: T0637
Synonym:
Target: Others
Otenaproxesul
Cat.No: T1867
Synonym: ATB 346
Target: Apoptosis, COX
4-Butoxyphenol
Cat.No: T1350
Synonym: 4-正丁氧基苯酚,P-Butoxyphenol
Target: Others
Edoxaban impurity 6
Cat.No: T37176
Synonym:
Target:
TargetMol Loading
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