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Search Results for " nrg1 "
Targets Recommended: EGFR

2

抑制剂 & 化合物

16

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T11761 Tarlox-TKI

Kinase inhibitor-1

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Tarlox-TKI (Kinase inhibitor-1) 是一种 pan-ErbB 抑制剂,是 Tarloxotinib 的活性成分,具有抗肿瘤活性。Tarlox-TKI 抑制 NRG1,抑制HER2 突变体。
T76791 Seribantumab

Seribantumab (MM 121) 是一种完全人 IgG2单克隆抗体,靶向 HER3。Seribantumab 阻断 ErbB 家族成员及其下游信号的激活。Seribantumab 在体内、外抑制乳腺癌、肺癌和卵巢癌患者源性癌症模型中神经调节蛋白 (NRG1) 融合依赖的肿瘤发生。

化合物

Tarlox-TKI
Cat.No: T11761
Synonym: Kinase inhibitor-1
Target: EGFR
Seribantumab
Cat.No: T76791
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-02721 NRG1 alpha Protein, Human, Recombinant (His)

HRGA,NDF,neuregulin 1,SMDF,NRG1 α...

Human HEK293 Cells
NRG1 alpha Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.5kDa and the accession number is Q02297-1.
TMPY-03010 NRG1 beta 1 Protein, Human, Recombinant

NDF,GGF,MSTP131,Neuregulin 1,MST<...

Human HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.8 kDa and the accession number is Q02297-6.
TMPY-02720 NRG1 alpha Protein, Human, Recombinant (hFc)

MST131,HRG1,NRG1

Human HEK293 Cells
NRG1 alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 51 kDa and the accession number is Q02297-1.
TMPY-02600 NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc)

neuregulin 1,HRGA,NRG1 β1

Human HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 36.7 kDa and the accession number is Q02297-6.
TMPY-02705 NRG1 beta 1 Protein, Human, Recombinant (hFc)

MSTP131,HRG1,NRG1

Human HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 55.2 kDa and the accession number is Q02297-6.
TMPJ-00448 NRG1 beta 1 Protein, Human, Recombinant (aa 2-246)

NRG1β,HGL,NDF,NRG1,HRGA,...

Human E. coli
Pro-neuregulin-1,Neuregulin-1 beta 1NRG1) is a single-pass type I membrane protein and belongs to the neuregulin family .It contains 1 EGF-like domain and 1 Ig-like C2-type (immunoglobulin-like) domain. Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. The protein concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and ...
TMPY-02719 NRG1 alpha Protein, Human, Recombinant (EGF Domain, hFc)

HRG1,NRG1-IT2,HRGA,NRG

Human HEK293 Cells
NRG1 alpha Protein, Human, Recombinant (EGF Domain, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 35.8 kDa and the accession number is Q02297-1.
TMPY-05813 Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated

HGL,NRG1-IT2,MST131,NDF,...

Human HEK293 Cells
Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.8 kDa and the accession number is Q02297.
TMPY-00031 Neuregulin-1/NRG1 Protein, Human, Recombinant (His)

HRG1,GGF2,HRG,NDF,MSTP131,HRGA,GG...

Human HEK293 Cells
Neuregulin-1/NRG1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.3 kDa and the accession number is Q02297-12.
TMPY-00479 Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)

ARIA,neuregulin 1,GGF2,MSTP131,GG...

Human HEK293 Cells
Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.5 kDa and the accession number is Q02297-12.
TMPY-04088 Neuregulin-1/NRG1 Protein, Canine, Recombinant

neuregulin 1

Canine HEK293 Cells
Neuregulin-1/NRG1 Protein, Canine, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.7 kDa and the accession number is XP_858147.1.
TMPY-03943 Neuregulin-1/NRG1 Protein, Canine, Recombinant (hFc)

neuregulin 1

Canine HEK293 Cells
Neuregulin-1/NRG1 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.8 kDa and the accession number is XP_858147.1.
TMPY-03902 Neuregulin-1/NRG1 Protein, Canine, Recombinant (mFc)

neuregulin 1

Canine HEK293 Cells
Neuregulin-1/NRG1 Protein, Canine, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 34 kDa and the accession number is XP_858147.1.
TMPY-03903 Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 19-240, His)

neuregulin 1

Canine HEK293 Cells
Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 19-240, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.5 kDa and the accession number is XP_858147.1.
TMPY-04237 Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 176-240, His)

neuregulin 1

Canine HEK293 Cells
Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 176-240, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 9.7 kDa.
TMPH-01536 ITGB4 Protein, Human, Recombinant (His & Myc)

Human E. coli
Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling.

重组蛋白

NRG1 alpha Protein, Human, Recombinant (His)
Cat.No: TMPY-02721
Species: Human
Expression System: HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant
Cat.No: TMPY-03010
Species: Human
Expression System: HEK293 Cells
NRG1 alpha Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02720
Species: Human
Expression System: HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc)
Cat.No: TMPY-02600
Species: Human
Expression System: HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02705
Species: Human
Expression System: HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant (aa 2-246)
Cat.No: TMPJ-00448
Species: Human
Expression System: E. coli
NRG1 alpha Protein, Human, Recombinant (EGF Domain, hFc)
Cat.No: TMPY-02719
Species: Human
Expression System: HEK293 Cells
Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated
Cat.No: TMPY-05813
Species: Human
Expression System: HEK293 Cells
Neuregulin-1/NRG1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00031
Species: Human
Expression System: HEK293 Cells
Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00479
Species: Human
Expression System: HEK293 Cells
Neuregulin-1/NRG1 Protein, Canine, Recombinant
Cat.No: TMPY-04088
Species: Canine
Expression System: HEK293 Cells
Neuregulin-1/NRG1 Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-03943
Species: Canine
Expression System: HEK293 Cells
Neuregulin-1/NRG1 Protein, Canine, Recombinant (mFc)
Cat.No: TMPY-03902
Species: Canine
Expression System: HEK293 Cells
Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 19-240, His)
Cat.No: TMPY-03903
Species: Canine
Expression System: HEK293 Cells
Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 176-240, His)
Cat.No: TMPY-04237
Species: Canine
Expression System: HEK293 Cells
ITGB4 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01536
Species: Human
Expression System: E. coli
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