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Search Results for " npp1 "

10

抑制剂 & 化合物

6

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T61782	NPP1-IN-1
	NPP1-IN-1 is a highly potent inhibitor of NPP enzymes, effectively inhibiting NPP1 with an IC 50 value of 0.15 μM and NPP3 with an IC 50 value of 40 μM [1].
T14022	2OH-BNPP1	Others	Others
	2OH-BNPP1 是BUB1 kinase 抑制剂，可用于研究癌症。
T69560	ENPP1 inhibitor 43
	ENPP1 inhibitor 43 is a novel small molecule for cancer immunotherapy.
T37431	ENPP1 Inhibitor C ENPP1 Inhibitor C
	ENPP1 inhibitor C is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; IC50 = 0.26 μM in a cell-free assay).1 It is selective for ENPP1 over ENPP2-7 at 10 μM. ENPP1 inhibitor C decreases ENPP1 activity in MDA-MB-231 human breast and C6 rat glioma cancer cells when used at a concentration of 10 μM. \|1. Kawaguchi, M., Han, X., Hisada, T., et al. Development of an ENPP1 fluorescence probe for inhibitor screening, cellular imaging, and prognostic assessment of malignant brea...
T67775	Enpp/Carbonic anhydrase-IN-1	PDE; Carbonic Anhydrase	Metabolism
	Enpp/Carbonic anhydrase-IN-1 (compound 1e) 是有效的 Enpp 和 carbonic anhydrase 抑制剂。Enpp/Carbonic anhydrase-IN-1抑制 NPP1、NPP2、NPP3、CA-II、CA-IX 的 IC50 值分别 1.36、1.35、3.00、0.88、1.02 µM。Enpp/Carbonic anhydrase-IN-1 选择性抑制癌细胞的增殖，对正常细胞毒性较低。
T77631	Enpp/Carbonic anhydrase-IN-2	Apoptosis; PDE; Carbonic Anhydrase	Apoptosis; Metabolism
	Enpp/Carbonic anhydrase-IN-2 is a potent dual inhibitor of Enpp and carbonic anhydrase, inhibiting NPP1, NPP2, NPP3, CA-IX, CA-XII, with IC50 values of 1.13, 1.07, 0.74, 0.33, 0.68, respectively.Enpp/Carbonic anhydrase-IN-2 induced apoptosis.Enpp/Carbonic anhydrase-IN-2 has antiproliferative activity against cancer cells and low cytotoxicity against normal cells.
T14320	ARL67156 trisodium salt	Others	Others
	ARL 67156 is a weak competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12 μM, respectively[1]. ARL67156 trisodium salt is an inhibitor of ecto-ATPase.
T73645	ARL67156 triethylamine
	ARL67156 (FPL 67156) triethylamine 是一种ecto-ATPase 抑制剂。ARL67156 triethylamine 是竞争性 NTPDase1 (CD39)，NTPDase3 和 NPP1 抑制剂，Ki 分别为 11，18 和 12 μM。ARL67156 triethylamine 可用于钙化性主动脉瓣疾病、哮喘等疾病的研究。
T72164	Enpp/Carbonic anhydrase-IN-2
	Enpp/Carbonic anhydrase-IN-2 是一种有效的 Enpp 和 carbonic anhydrase 抑制剂，对 NPP1、NPP2、NPP3、CA-IX, CA-XII 的 IC50值分别 1.13、 1.07、 0.74、 0.33、 0.68。Enpp/Carbonic anhydrase-IN-2 对癌细胞具有抗增殖活性，对正常细胞具有低细胞毒性。Enpp/Carbonic anhydrase-IN-2 诱导细胞凋亡 (Apoptosis)。
T73644	ARL67156 trisodium hydrate
	ARL67156 (FPL 67156) trisodium hydrate 是一种ecto-ATPase 抑制剂。ARL67156 trisodium hydrate 是竞争性 NTPDase1 (CD39)，NTPDase3 和 NPP1 抑制剂，Ki 分别为 11，18 和 12 μM。ARL67156 trisodium hydrate 可用于钙化性主动脉瓣疾病、哮喘等疾病的研究。

化合物

Cat.No: T61782

Cat.No: T14022

Target: Others

ENPP1 inhibitor 43

Cat.No: T69560

ENPP1 Inhibitor C

Cat.No: T37431

Synonym: ENPP1 Inhibitor C

Enpp/Carbonic anhydrase-IN-1

Cat.No: T67775

Target: PDE, Carbonic Anhydrase

Enpp/Carbonic anhydrase-IN-2

Cat.No: T77631

Target: Apoptosis, PDE, Carbonic Anhydrase

ARL67156 trisodium salt

Cat.No: T14320

Target: Others

ARL67156 triethylamine

Cat.No: T73645

Enpp/Carbonic anhydrase-IN-2

Cat.No: T72164

ARL67156 trisodium hydrate

Cat.No: T73644

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00852	ENPP1 Protein, Human, Recombinant (His & Avi), Biotinylated E-NPP 1,NPPase,PC1,N...	Human	HEK293 Cells
	Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (ePPi). Mechanical stimulation regulates ENPP-1 expression. ENPP1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 98.29 kDa and the accession number is P22413.
TMPK-00854	ENPP1 Protein, Human, Recombinant (C-His) M6S1,E-NPP 1,PCA1,PDNP	Human	HEK293 Cells
	Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (ePPi). Mechanical stimulation regulates ENPP-1 expression. ENPP1 Protein, Human, Recombinant (C-His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 96.5 kDa and the accession number is P22413.
TMPK-00781	ENPP1 Protein, Mouse, Recombinant (His) ENPP1,PC1,PCA1ARHR2,PCA<...	Mouse	HEK293 Cells
	Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (ePPi). Mechanical stimulation regulates ENPP-1 expression. ENPP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 95.99 kDa and the accession number is P06802-1.
TMPK-00853	ENPP1 Protein, Human, Recombinant (N-His) PDNP1,NPP1,NPPase,PCA	Human	HEK293 Cells
	Ectonucleotide pyrophosphatase/phosphodiesterase (ENPP)-1 is a membrane-bound protein that catalyzes the hydrolysis of extracellular nucleoside triphosphates to monophosphate and extracellular inorganic pyrophosphate (ePPi). Mechanical stimulation regulates ENPP-1 expression. ENPP1 Protein, Human, Recombinant (N-His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 96.5 kDa and the accession number is P22413.
TMPJ-00984	INPP1 Protein, Human, Recombinant (His) IPP,IPPase,Inositol Polyphosphate 1-Phosphatase,I	Human	HEK293 Cells
	Inositol Polyphosphate 1-Phosphatase (INPP1) is a member of the inositol monophosphatase family. INPP1 is widely expressed in tissues, with highest expression levels observed in the pancreas and kidney. INPP1 is inhibited by Li+. Removing the phosphate group at position 1 of the inositol ring from the polyphosphates inositol 1,4-bisphosphate and inositol 1,3,4-trisphophosphate. INPP1 is involved in signal transduction and phosphatidylinositol signaling pathway.
TMPJ-01390	MINPP1 Protein, Human, Recombinant (His) 3,4,5)-Tetrakisphosphate 3-Phosphatase,2,5)P(4) 3-Phosphatas...	Human	HEK293 Cells
	Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and re...

重组蛋白

ENPP1 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00852

Species: Human

Expression System: HEK293 Cells

ENPP1 Protein, Human, Recombinant (C-His)

Cat.No: TMPK-00854

Species: Human

Expression System: HEK293 Cells

ENPP1 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00781

Species: Mouse

Expression System: HEK293 Cells

ENPP1 Protein, Human, Recombinant (N-His)

Cat.No: TMPK-00853

Species: Human

Expression System: HEK293 Cells

INPP1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00984

Species: Human

Expression System: HEK293 Cells

MINPP1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01390

Species: Human

Expression System: HEK293 Cells

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