首页工具

登录

搜索结果

Search Results for " ngal "

Targets Recommended: Antifungal Influenza Virus Monoamine Transporter

71

抑制剂 & 化合物

2

天然产物

2

化合物库

1

TargetMol 试剂盒

5

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name
L6001	Mini真菌代谢天然产物筛选库		Inquiry

L4500	抗真菌库		252 compounds
	252 个抗真菌活性化合物的独特集合，包含作用于真菌相关靶点的化合物和临床中用于真菌类疾病的药物，是相关疾病药物筛选的有效工具。

化合物库

Mini真菌代谢天然产物筛选库

Cat.No: L6001

Compounds: Inquiry

Cat.No: L4500

Compounds: 252

Cat. No.	Product Name	Form	Specificity Of Inhibition
CL0065	Antifungal compound kit Antifungal compound kit

TargetMol 试剂盒

Antifungal compound kit

Cat.No: CL0065

Cat. No.	Product Name	Target	Signaling Pathways
T7651	Rose Bengal sodium Rose Bengal,酸性红 94	Influenza Virus; Monoamine Transporter	Membrane transporter/Ion channel; Microbiology/Virology
	Rose Bengal sodium 是一种合成的荧光素衍生物，主要成分是 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo 荧光素，可以检测眼表干燥或受损的细胞，用作眼科诊断剂，具有抗病毒活性。它是一种 VGlut 和囊泡单胺转运蛋白抑制剂，VGlut 和 VMAT 的 Ki 分别为 19 和 64 nM。
T9274	antifungal-agent-6 N-(2-BENZO[1,3]DIOXOL-5-YL-ETHYL)-2-(4-METHYL-BENZYL)-SUCCINAMIC ACID	Antibacterial; Antifungal	Microbiology/Virology
	Antifungal agent 6 是抗菌剂。
T83071	Antifungal agent 62
	Antifungalagent 62 (Compound 3a) 是针对Fusarium oxysporum f.sp. cucumerinum展现出卓越抑制效果的杀菌剂，适用于抗病毒及杀菌机制研究。
T83066	Antifungal agent 82
	Antifungalagent 82 (compound G34)是一种高效的抗真菌剂，对Valsa mali具有显著的体外活性，其EC50值仅为0.57 μg/mL。该化合物在40 mg/L的浓度下，还能够有效地在体内保护植物免受V. mali的侵害。
T63285	Antifungal agent 40
	Antifungal agent 40 是抗真菌剂，能够延伸到 C.alb.CYP51 的狭窄疏水口袋 II 中，可抑制 lanosterol 14α-demethylase (CYP51) 的活性，对生物膜的形成具有抑制作用。
T63802	Antifungal agent 35
	Antifungal agent 35 是一种使氟康唑对C. albicans 的抗真菌活性的有效增强剂，是有效的抗真菌剂。
T74272	Antifungal agent 84
	Antibacterial agent 84 是一种抗真菌化合物。Antibacterial agent 84 以 CNB1 依赖性方式抑制念珠菌。Antibacterial agent 84 抑制C. albicans 生物膜的活性。
T74772	Antifungal agent 47
	Antifungal agent 47 (compound 3b) 表现出极高的广谱杀真菌活性、强呼吸抑制活性和腺苷5'-三磷酸合成抑制活性。 Antifungal agent 47 具有作为杀菌剂的潜力。
T75181	Antifungal agent 58
	Antifungal agent 58 (compound A21) 是一种抗氟康唑耐药菌株的强效抗真菌剂。Antifungal agent 58 比咪康唑更有效。Antifungal agent 58 抑制白色念珠菌的 MIC 值为 0.06-8 μg/mL。
T78893	Antifungal agent 78
	Antifungalagent 78（compound 25am）作为一种抗真菌剂，其针对禾谷镰刀菌具有EC50值为13.46 μM。
T78115	Antifungal agent 48
	Antifungalagent 48 (Example 112)是一种针对Cryptococcus neoformans的抗真菌剂，展现出MIC为11 μM的抗菌活性。
T79384	Antifungal agent 72
	Antifungalagent 72（Compound B8）是一款高效抗真菌药物。该化合物通过抑制Pdr1-KIX相互作用（Ki：11.7μM）来干扰外排泵功能，并降低与耐药性相关的基因表达。Antifungalagent 72对抗氟康唑（Fluconazole）耐药的C. glabrata 0161菌株显示出显著的抗菌活性，其MIC值为63 ng/mL，并与氟康唑合用时表现出协同效果。此化合物可应用于C. glabrata感染的相关研究。
T40262	Antifungal agent 15
	Antifungal agent 15 exhibits remarkable potency, with EC50 values of 0.52 and 0.50 μg/mL against S. sclerotiorum and B. cinerea, respectively.
T40124	Antifungal agent 20
	Antifungal agent 20 demonstrates significant antifungal efficacy against a range of fungal pathogens including Colletotrichum gloeosprioides, Rhizoctonia solani, Phytophthora nicotianae var. nicotianae, Diplodia pinea, Colletotrichum acutatum, and Fusarium oxysporum f. sp. niveum.
T63314	Antifungal agent 31
	Antifungal agent 31 是口服具有活力的、拥有吡咯三嗪酮支架的三唑类抗真菌剂，对念珠菌和丝状真菌表现出一定的抗真菌作用。Antifungal agent 31 能够明显减少两种致死性全身感染小鼠模型的死亡率和肾脏真菌负担。
T83070	Antifungal agent 63
	Antifungalagent 63 (Compound 3i) 是针对 Fusarium oxysporum f.sp. cucumerinum 展现出优异杀菌活性的抗真菌剂，适用于抗病毒与杀菌领域的研究。
T79522	Antifungal agent 65
	Antifungalagent 65 (Compound 5d) 是一种针对Fusarium oxysporum f.sp. cucumerinum表现出优异杀菌活性的抗真菌化合物，可应用于抗病毒与杀菌研究。
T74976	Antifungal agent 46	Ras	GPCR/G Protein; MAPK
	Antifungalagent 46 (compound 2f)是一种通过抑制farnesyltransferase从而抑制Ras信号的有效抗真菌剂。
T79759	Antifungal agent 74
	Antifungalagent 74 (compound 3c) 是一种高效抗真菌化合物，展现出对C. arachidicola和R. solani的显著杀菌效果。其机制主要通过破坏真核生物的类固醇生物合成及核糖体生物发生来实现。
T79552	Antifungal agent 70
	Antifungalagent 70 (compound 13) 是具有抗多重耐药性耳念珠菌功能的二氢丁香酚-咪唑，其最小抑菌浓度 (MIC) 为 36.4 μM，展现了其抗真菌活性。
T78116	Antifungal agent 49
	Antifungalagent 49（Example 112），一种针对Cryptococcus neoformans新型隐球菌具有活性的抗真菌剂，其MIC值为49 μM。
T79521	Antifungal agent 64
	Antifungalagent 64 (Compound 5c) 对Fusarium oxysporum f.sp. cucumerinum 表现出优异的抗菌活性，主要应用于抗病毒和杀菌领域的研究。
T40329	Antifungal agent 14
	Antifungal agent 14 demonstrates potent broad-spectrum antifungal activity, effectively targeting a variety of fungal strains with exceptional minimum inhibitory concentration values.
T74273	Antifungal agent 52
	Antifungal agent 52 (compound 6c) 是四唑衍生物。Antifungal agent 52 抑制麦角固醇的合成。Antifungal agent 52 对白色念珠菌表现出显着的抗真菌活性 Antifungal agent 52 影响白色念珠菌基底细胞膜通透性。
T83068	Antifungal agent 77
	Antifungalagent 77 (Compound 13h) 作为一种化合物，展现出对粘虫、棉铃虫、玉米螟及草地贪夜蛾的杀虫效力，其浓度为500 μg/mL时，相应的死亡率为30%、25%、40% 和 25%。同时，该化合物对斑马鱼胚胎具有毒性，其半致死浓度（LC50）为2.43 μg/mL。
T60236	Antifungal agent 38
	Antifungal agent 38 是一种环二硫化物，具有抗真菌和抗细菌活性。Antifungal agent 38 能诱导菌丝收缩，破坏质膜的完整性，并导致细胞内容物的破坏和渗漏。
T62211	Antifungal agent 33
	Antifungal agent 33 (compound 4e) 是一种有效的抗真菌剂。Antifungal agent 33 对白念珠菌具有明显的抗真菌作用 (MIC: 16 μg/ml)。Antifungal agent 33 能够较强的抑制羊毛甾醇 14α-去甲基化酶 (CYP51) (IC50: 0.19 μg/ml)。
T62098	Antifungal agent 28
	Antifungal agent 28 (化合物 18) 是一种选择性的、有效的抗真菌剂。Antifungal agent 28 可以破坏成熟念珠菌生物膜，能够抑制白念珠菌和非白念珠菌的致病性菌株，包括耐氟康唑菌株。Antifungal agent 28 对隐球菌和曲霉菌株也具有抑制作用。
T61257	Antifungal agent 19
	Antifungal agent 19 显示出强大的抗真菌活性（EC50= 0.72 μM）。
T62280	Antifungal agent 17
	Antifungal agent 17 对 B. cinerea 表现出很好的抗真菌效果 (EC50: 2.86 μg/mL)。
T83065	Antifungal agent 85
	Antifungalagent 85 (compound 24f)是一种抗真菌剂，对多种革兰氏阳性菌表现出良好的活性，其最小抑制浓度(MIC)范围为2.5 - 10?μM。
T64235	Antifungal agent 25
	Antifungal agent 25 是一种有效的、广谱的、体内具有代谢稳定性的抗真菌剂。Antifungal agent 25 对白色念珠菌和耐氟康唑的白色念珠菌都表现出抗真菌效果。
T74537	Antifungal agent 26
	Antifungal agent 26, a derivative of gramicidin A, exhibits antifungal, antiviral, and antiparasitic activities through binding with polysaccharides containing D-mannose (Man) in pathogens.
T79550	Antifungal agent 68
	Antifungalagent 68（compound 10）是抗真菌剂，针对念珠菌和格特隐球菌。它通过抑制麦角甾醇的生物合成发挥作用，靶向羊毛甾醇 14α-去甲基酶（CYP51）。Antifungalagent 68的咪唑环能与CYP51的血红素基团发生相互作用。
T79549	Antifungal agent 67
	Antifungalagent 67 (compound 9) 是一种抑制念珠菌有效的咪唑类抗真菌剂，其对健康新生大鼠成心肌细胞的 CC50 值为 33.6 μM。
T79413	Antifungal agent 73
	Antifungalagent 73 (compound A32)是一款用于治疗唑类耐药Candida感染的抗真菌药物。该化合物通过破坏真菌的细胞壁和细胞膜来发挥作用，并且针对病原真菌和氟康唑(Fluconazole)耐药菌株显示出有效的体内抗真菌活性。
T74526	Antifungal agent 29
	Antifungal agent 29 (化合物 9d) 是一种有效的、选择性的、无毒的抗真菌剂。Antifungal agent 29 对新隐球菌具有抗真菌活性 (MIC≤ 0.23 μM)。
T74831	Antifungal agent 51
	Antifungal agent 51 (5c) 具有强效的抗真菌活性，尤其是对白色念珠菌 FDC 151 、近平滑念珠菌 ATCC 22019 和热带假丝酵母 FDC 138，MIC 值小于 0.063 μg/mL，而对细胞的毒性较低，无致癌性。
T75177	Antifungal agent 54
	Antifungal agent 54 (compound A05) 是一种抗氟康唑耐药菌株的强效抗真菌剂。Antifungal agent 54 比咪康唑更有效。Antifungal agent 54 抑制白色念珠菌的 MIC 值为 0.25-1 μg/mL。
T78908	Antifungal agent 50
	Antifungalagent 50，MIC值范围<0.063-1 μg/mL，具有高效的抗真菌活性。
T79298	Antifungal agent 61
	Antifungalagent 61 (Compound 38)是一种有效的抗真菌剂，其对V. mali的EC50值为0.50 mg/L。该化合物通过诱导细胞畸变和收缩、减少线粒体数量、增厚细胞壁和提高细胞膜透性来实现其抑制作用。
T62159	Antifungal agent 24
	Antifungal agent 24 (Compound 6) 是一种抗真菌剂，能够抑制白色念珠菌 (MIC: 0.03 μg/ml)。
T64029	Antifungal agent 42
	Antifungal agent 42 是一种抗真菌剂，对生物膜形成具有抑制作用。Antifungal agent 42 能够抑制 C.alb.的 lanosterol 14α-demethylase (CYP51)。
T83067	Antifungal agent 81
	Antifungalagent 81(G22) 对马利弧菌显示出显著的体外抑制活性，其IC50为0.48 mg/L。在体内，以40 mg/L的剂量，Antifungalagent 81同样展现出对马里弧菌的良好保护效果。
T63627	Antifungal agent 11
	Antifungal agent 11 拥有良好的抗真菌效果。
T61308	Antifungal agent 27
	Antifungal agent 27 (compound 7) is a chemical compound possessing antifungal properties. It exhibits moderate antibacterial activity and weak antifungal activity against MRSA and C. albicans SS5314, with minimal inhibitory concentration (MIC) values of 8 and 32 μg/mL, respectively [1].
T79551	Antifungal agent 69
	Antifungalagent 69 (compound 13)，作为一种丁子香酚-咪唑类化合物，对白色念珠菌表现出有效的抗真菌活性，其MIC值为4.6 μM，并未展现显著的细胞毒性。此外，该化合物能够干预真菌的麦角甾醇生物合成路径。
T75176	Antifungal agent 53
	Antifungal agent 53 (A03) 是一种有效的白色念珠菌 CYP51抑制剂，具有抗真菌活性。Antifungal agent 53 阻止真菌生物膜的形成。Antifungal agent 53 也显示出良好的安全性。
T75179	Antifungal agent 56
	Antifungal agent 56 (compound A09) 是一种抗氟康唑耐药菌株的强效抗真菌剂。Antifungal agent 56 比咪康唑更有效。Antifungal agent 56 抑制白色念珠菌的 MIC 值为 0.03-0.25 μg/mL。
T75178	Antifungal agent 55
	Antifungal agent 55 (compound A07) 是一种抗氟康唑耐药菌株的强效抗真菌剂。Antifungal agent 55 比咪康唑更有效。Antifungal agent 55 抑制白色念珠菌的 MIC 值为 0.25-1 μg/mL。

化合物

Rose Bengal sodium

Cat.No: T7651

Synonym: Rose Bengal,酸性红 94

Target: Influenza Virus, Monoamine Transporter

antifungal-agent-6

Cat.No: T9274

Synonym: N-(2-BENZO[1,3]DIOXOL-5-YL-ETHYL)-2-(4-METHYL-BENZYL)-SUCCINAMIC ACID

Target: Antibacterial, Antifungal

Antifungal agent 62

Cat.No: T83071

Antifungal agent 82

Cat.No: T83066

Antifungal agent 40

Cat.No: T63285

Antifungal agent 35

Cat.No: T63802

Antifungal agent 84

Cat.No: T74272

Antifungal agent 47

Cat.No: T74772

Antifungal agent 58

Cat.No: T75181

Antifungal agent 78

Cat.No: T78893

Antifungal agent 48

Cat.No: T78115

Antifungal agent 72

Cat.No: T79384

Antifungal agent 15

Cat.No: T40262

Antifungal agent 20

Cat.No: T40124

Antifungal agent 31

Cat.No: T63314

Antifungal agent 63

Cat.No: T83070

Antifungal agent 65

Cat.No: T79522

Antifungal agent 46

Cat.No: T74976

Target: Ras

Antifungal agent 74

Cat.No: T79759

Antifungal agent 70

Cat.No: T79552

Antifungal agent 49

Cat.No: T78116

Antifungal agent 64

Cat.No: T79521

Antifungal agent 14

Cat.No: T40329

Antifungal agent 52

Cat.No: T74273

Antifungal agent 77

Cat.No: T83068

Antifungal agent 38

Cat.No: T60236

Antifungal agent 33

Cat.No: T62211

Antifungal agent 28

Cat.No: T62098

Antifungal agent 19

Cat.No: T61257

Antifungal agent 17

Cat.No: T62280

Antifungal agent 85

Cat.No: T83065

Antifungal agent 25

Cat.No: T64235

Antifungal agent 26

Cat.No: T74537

Antifungal agent 68

Cat.No: T79550

Antifungal agent 67

Cat.No: T79549

Antifungal agent 73

Cat.No: T79413

Antifungal agent 29

Cat.No: T74526

Antifungal agent 51

Cat.No: T74831

Antifungal agent 54

Cat.No: T75177

Antifungal agent 50

Cat.No: T78908

Antifungal agent 61

Cat.No: T79298

Antifungal agent 24

Cat.No: T62159

Antifungal agent 42

Cat.No: T64029

Antifungal agent 81

Cat.No: T83067

Antifungal agent 11

Cat.No: T63627

Antifungal agent 27

Cat.No: T61308

Antifungal agent 69

Cat.No: T79551

Antifungal agent 53

Cat.No: T75176

Antifungal agent 56

Cat.No: T75179

Antifungal agent 55

Cat.No: T75178

Cat. No.	Product Name	Target	Signaling Pathways
T3747	syringaldehyde Syringic aldehyde,丁香醛,Springaldehyde	COX	Immunology/Inflammation; Neuroscience
	syringaldehyde 是可从厚朴和木薯中分离得到的黄酮类多酚，具有抗氧化、抗高血糖和抗炎活性，可适度抑制COX-2活性，IC50为 3.5 μg/mL。
TQ0072	Warangalone Scandenolone,攀登鱼藤异黄酮	PKA	Tyrosine Kinase/Adaptors
	Warangalone is an anti-malarial compound that can inhibit the growth of both strains of parasite 3D7 (chloroquine-sensitive) and K1 (chloroquine-resistant) with IC50s of 4.8 μg/mL and 3.7 μg/mL, respectively.

天然产物

Cat.No: T3747

Synonym: Syringic aldehyde,丁香醛,Springaldehyde

Target: COX

Cat.No: TQ0072

Synonym: Scandenolone,攀登鱼藤异黄酮

Target: PKA

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00873	Lipocalin-2/LCN2 Protein, Human, Recombinant (His) MSFI,24p3,lipocalin 2,NGAL,Lipocalin-2,p25	Human	HEK293 Cells
	Lipocalin-2/LCN2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P80188-1.
TMPK-00085	NGAL/Lipocalin-2 Protein, Human, Recombinant (hFc) NGAL,Lipocalin-2,Oncogene 24p3,MSFI,Siderocalin LCN...	Human	HEK293 Cells
	NGAL/Lipocalin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 47.2 kDa and the accession number is P80188-1.
TMPK-01289	NGAL/Lipocalin-2 Protein, Cynomolgus, Recombinant (His) Siderocalin LCN2,Oncogene 24p3,Lipocalin-2,p25,MSFI,NGAL...	Cynomolgus	HEK293 Cells
	NGAL/Lipocalin-2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 21.51 kDa and the accession number is XP_005580845.3.
TMPJ-00082	NGAL/Lipocalin-2 Protein, Mouse, Recombinant (hFc) Lipocalin-2,SV-40-induced 24P3 protein,Siderocalin LCN2,LCN2...	Mouse	HEK293 Cells
	Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), is a secretory protein of the lipocalin superfamily. Lipocalin-2 contains a signal peptide that enables it to be secreted and form complexes with matrix metalloproteinase-9 (MMP-9) through disulfide bonds. Similar to other lipocalin family members, Lipocalin-2 is involved in diverse cellular processes, including the transport of small hydrophobic molecules, protection of MMP-9 from proteolytic degradation, and cell sig...
TMPH-00121	Antifungal Protein, Aspergillus giganteus, Recombinant (B2M & His) afp,Antifungal protein	Aspergillus giganteus	E. coli
	This protein inhibits the growth of a variety of fungal species. Antifungal Protein, Aspergillus giganteus, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 19.8 kDa and the accession number is P17737.

重组蛋白

Lipocalin-2/LCN2 Protein, Human, Recombinant (His)

Cat.No: TMPY-00873

Species: Human

Expression System: HEK293 Cells

NGAL/Lipocalin-2 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00085

Species: Human

Expression System: HEK293 Cells

NGAL/Lipocalin-2 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01289

Species: Cynomolgus

Expression System: HEK293 Cells

NGAL/Lipocalin-2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00082

Species: Mouse

Expression System: HEK293 Cells

Antifungal Protein, Aspergillus giganteus, Recombinant (B2M & His)

Cat.No: TMPH-00121

Species: Aspergillus giganteus

Expression System: E. coli

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼