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11

抑制剂 & 化合物

5

天然产物

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Cat. No. Product Name Target Signaling Pathways
T33213 Mannitol myleran

Busulfan mannitol,Mannitolbusulfan,AI3-51861

Mannitol myleran is a reagent used in the preparation of pharmaceutical compounds for tumor diagnosis and treatment.
T40739 L-Mannitol

L-mannitol is a compound can be used for the compound sweetener synthesis.
T37783 2,5-Anhydro-D-mannitol

2,5-Anhydro-D-mannitol is an antimetabolic fructose analogue that increases food intake in rats at doses of 50-800 mg/kg by inhibiting gluconeogenesis and glycogenolysis in the liver.. It is phosphorylated in the liver, which decreases available ATP and signals eating behavior in rats through a vagal nerve mechanism.
T23990 Dianhydromannitol

1:2:5:6-Dianhydro-D-mannitol,DADM,NSC-133129,UNII-DPHVJPYRKV

Dianhydromannitol, Dihyro- and tetrahydrofuran building blocks from 1,4:3,6-dianhydromannitol.
T65261 1,4:3,6-Dianhydro-D-mannitol

1,4:3,6-Dianhydro-D-mannitol 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65261,CAS号为 641-74-7。
T21089 Nitrophenide

3,3'-Dinitrodiphenyl disulfide,3,3'-二硝基二苯二硫醚

Dehydrogenase Metabolism
Nitrophenide (3,3'-Dinitrodiphenyl disulfide) 抑制甘露醇-1-磷酸脱氢酶 (M1PDH),该酶催化甘露醇循环中的酶促步骤。 Nitrophenide 可用作抗球虫剂。
T16697 Pyronaridine tetraphosphate

Topoisomerase DNA Damage/DNA Repair
Pyronaridine tetraphosphate 是一种具有口服活性的、含甘露醇的DNA 拓扑异构酶 2 的抑制剂和红细胞裂殖杀灭剂,具有抗疟活性和抗肿瘤活性。Pyronaridine tetraphosphate 可治疗 P. falciparum 和 Echinococcus granulosus感染,可减轻埃博拉病毒传播。
T5493 Pyronaridine

Others Others
Pyronaridine 是一种具有口服活性的、含甘露醇的抗疟疾化合物,通过干扰红细胞内疟疾寄生虫(疟原虫)的复制而起作用。Pyronaridine 常与其他药联用来治疗疟疾,对对 P. falciparum 和 Echinococcus granulosus 具有抗感染活性。
T20256 Sorbitol, L-

L-Glucitol

Sorbitol, L- is a sugar alcohol. It can be obtained by the reduction of glucose, which changes the aldehyde group to a hydroxyl group. It is converted to fructose by sorbitol-6-phosphate 2-dehydrogenase. Sorbitol is an isomer of mannitol, another sugar al
T74024 2,5-Anhydro-D-glucitol-1,6-diphosphate

2,5-Anhydro-D-glucitol-1,6-diphosphate 为酵母丙酮酸激酶(Pyruvate Kinase)的有限刺激剂,并可作为 a 型2,5-anhydro-D-mannitol 1,6-bisphosphate的同系物。后者为丙酮酸激酶的有效变构激活剂。
T60731 Mitobronitol

Mitobronitol (Myelobromol; DBM) 是甘露醇的溴化类似物。Mitobronitol 是被归类为烷化剂的抗癌剂。Mitobronitol 具有骨髓抑制作用,可显著降低加速慢性粒细胞白血病异体骨髓移植的几种并发症的风险。

化合物

Mannitol myleran
Cat.No: T33213
Synonym: Busulfan mannitol,Mannitolbusulfan,AI3-51861
Target:
L-Mannitol
Cat.No: T40739
Synonym:
Target:
2,5-Anhydro-D-mannitol
Cat.No: T37783
Synonym:
Target:
Dianhydromannitol
Cat.No: T23990
Synonym: 1:2:5:6-Dianhydro-D-mannitol,DADM,NSC-133129,UNII-DPHVJPYRKV
Target:
1,4:3,6-Dianhydro-D-mannitol
Cat.No: T65261
Synonym:
Target:
Nitrophenide
Cat.No: T21089
Synonym: 3,3'-Dinitrodiphenyl disulfide,3,3'-二硝基二苯二硫醚
Target: Dehydrogenase
Pyronaridine tetraphosphate
Cat.No: T16697
Synonym:
Target: Topoisomerase
Pyronaridine
Cat.No: T5493
Synonym:
Target: Others
Sorbitol, L-
Cat.No: T20256
Synonym: L-Glucitol
Target:
2,5-Anhydro-D-glucitol-1,6-diphosphate
Cat.No: T74024
Synonym:
Target:
Mitobronitol
Cat.No: T60731
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T4959 DL-Mannitol

甘露醇,Mannitol

Others Others
DL-Mannitol 是由 D-mannitol 与 L-mannitol 通过 L-mannono-1, Clactone 还原得到的。
T0414 D-Mannitol

Mannite,Mannitol,D-甘露糖醇,Osmitrol

Apoptosis; Dehydrogenase; Endogenous Metabolite Apoptosis; Metabolism
D-Mannitol (Mannitol) 是与山梨醇相关的利尿剂和肾脏诊断辅助剂,具有较弱的肾脏血管扩张活性。
TSP-41077145 Podoblastin A (D-mannitol)

Podoblastin A (D-mannitol) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 TSP-41077145。
T78499 1,5-Anhydro-D-mannitol

1,5-Anhydro-D-mannitol为1,5-Anhydrosorbitol的非活性类似物,通常用作实验对照。1,5-Anhydrosorbitol则作为评估短期血糖控制的可靠指标。
T7964 Isomalt

异麦芽酮糖醇,Palatinitol,Palatinit

Others; Dehydrogenase Metabolism; Others
Isomalt (Palatinitol) 是无毒的、具有良好耐受性的多元醇和蛋白质稳定的赋形剂,在冷冻干燥过程中可适度稳定乳酸脱氢酶(LDH),并在储存期间表现更好。它传统上在食品工业中用作甜味剂,也在制药中用作压片赋形剂。

天然产物

DL-Mannitol
Cat.No: T4959
Synonym: 甘露醇,Mannitol
Target: Others
D-Mannitol
Cat.No: T0414
Synonym: Mannite,Mannitol,D-甘露糖醇,Osmitrol
Target: Apoptosis, Dehydrogenase, Endogenous Metabolite
Podoblastin A (D-mannitol)
Cat.No: TSP-41077145
Synonym:
Target:
1,5-Anhydro-D-mannitol
Cat.No: T78499
Synonym:
Target:
Isomalt
Cat.No: T7964
Synonym: 异麦芽酮糖醇,Palatinitol,Palatinit
Target: Others, Dehydrogenase
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