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Cat. No.	Product Name	Target	Signaling Pathways
T79602	MTP	Autophagy	Autophagy
	MTP作为一种PKM2抑制剂，能够通过激活caspase-3来诱导癌细胞发生凋亡（apoptosis），同时诱导自噬（autophagy）过程并提高ROS的产生量。此外，MTP对JAK2信号传递通路也有抑制作用。该化合物主要用于研究口腔鳞状细胞癌。
T35689	MTP 131 acetate	Others	Others
	MTP 131 acetate 是一种小的线粒体靶向四肽。
TP1095	Elamipretide MTP-131,RX-31,SS-31	Others	Others
	Elamipretide (MTP-131) 是一种线粒体靶向抗氧化四肽 (D-Arg-dimethylTyr-Lys-Phe-NH2)，可以减少有毒活性氧的产生并稳定心磷脂，具有血脑屏障渗透性。Elamipretide 是罕见病巴氏综合征的潜在治疗剂。
T8831	Elamipretide 2TFA MTP-131 2TFA,RX-31 2TFA,SS-31,MTP-131,SS-31 2TFA,Bendavia	Others	Others
	Elamipretide 2TFA (RX-31 2TFA) 是一种新型的线粒体靶向抗氧化剂。
T12037	Mifamurtide L-MTP-PE,MTP-PE,CGP 19835,米伐木肽	Others	Others
	Mifamurtide is a drug against osteosarcoma, is an immunomodulator with antitumor effects.
TP2332	Mifamurtide sodium hydrate L-MTP-PE,Mifamurtide,Muramyl tripeptide
	Mifamurtide protects mice against herpes simplex virus type 2. It also is a macrophage activator.
TP1096	Elamipretide TFA SS-31 (TFA),MTP-131 (TFA),RX-31 (TFA)	Others	Others
	Elamipretide TFA (RX-31 TFA) 是一种心磷脂过氧化物酶抑制剂和线粒体靶向肽[。
TP1095L	Elamipretide acetate MTP 131 acetate,Elamipretide acetate (736992-21-5 Free base)
	Elamipretide acetate (MTP 131 acetate) 是Elamipretide 衍生物。Elamipretide 是一种小的线粒体靶向四肽(D-Arg-dimethylTyr-Lys-Phe-NH2)，可用于研究减少有毒活性氧的产生和稳定心磷脂。
TP2332L	Mifamurtide sodium Muramyl tripeptide,CGP 19835A,L-MTP-PE,米伐木肽钠盐,Mepact,Junovan
	Mifamurtide sodium is a drug against osteosarcoma, a kind of bone cancer mainly affecting children and young adults. It was approved in Europe in March 2009.
T27719	KD-026 SLx 4090,SLx4090,KD026,SLx-4090	CETP	Metabolism
	KD-026 (SLx 4090) 是具有口服活性的、肠细胞特异性的微粒体甘油三酯转移蛋白 (MTP)抑制剂，IC50为 8.0 nM。KD-026 (SLx 4090) 在糖尿病2型中有研究的价值。
T13784	MTPPA M 5011	Others	Others
	MTPPA (M 5011) 是一种具有抗炎症和疼痛作用的化合物。
T23033	MTPG	Others	Others
	Group II/group III metabotropic glutamate receptor antagonist
T27601	IMTPPE SID-3712502,SID 3712502,SID3712502
	IMTPPE inhibits transcriptional activity and protein level of AR in C4-2 prostate cancer cells. It also inhibits AR-target gene expression.
T30506	BMS-212122 UNII-0Z473OO6GB,BMS212122,BMS 212122	CETP	Metabolism
	BMS-212122 (UNII-0Z473OO6GB) 是一种有效的微粒体甘油三酯转移蛋白(MTP )抑制剂，在动物实验中显示出降血脂作用。BMS-212122 显著减少动脉粥样硬化斑块中的脂质含量和单核细胞衍生(CD68+)细胞。
T6267	Lomitapide AEGR-733,洛美他派,BMS-201038	CETP	Metabolism
	Lomitapide (AEGR-733) 是一种高效的微粒体甘油三酯转移蛋白(MTP)抑制剂，体内试验的IC50值为8 nM。
T31992	Granotapide	CETP	Metabolism
	Granotapide 是一种微粒体甘油三酯转移蛋白（MTP）抑制剂，治疗和而预防动脉硬化，冠状动脉疾病，代谢综合征，肥胖，糖尿病，糖尿病前期和高血压。
T15006	Dirlotapide CP742033,Slentrol	Others; CETP	Metabolism; Others
	Dirlotapide (CP742033) 是一种肠道选择性微粒体甘油三酯转移蛋白(MTP)抑制剂。它可以减轻糖尿病狗的体重。Dirlotapide 以剂量依赖性方式减少食物摄入量，可能是通过增加肽YY 释放到循环中。
T2545	Lomitapide Mesylate 甲磺酸洛美他派,BMS-201038 mesylate,AEGR-733 mesylate	CETP	Metabolism
	Lomitapide Mesylate (BMS-201038 mesylate) 是一种高效MTP 蛋白抑制剂，其体外IC50值为8 nM。
T38666	CP-346086 dihydrate
	CP-346086 dihydrate is a potent and orally active inhibitor of microsomal triglyceride transfer protein (MTP), exhibiting an IC50 value of 2.0 nM for both human and rodent MTP. This compound effectively lowers plasma cholesterol and triglyceride levels in vivo.
T10504	Implitapide Racemate	Others	Others
	Implitapide Racemate is the racemate of Implitapide. Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).
T16158	PF-02575799	Adenosine Receptor	GPCR/G Protein; Neuroscience
	PF-02575799 is an inhibitor of microsomal triglyceride transfer protein (MTP) (IC50: 0.77±0.29 nM).
T39303	CP-346086
	CP-346086 is a highly potent and orally bioavailable inhibitor of microsomal triglyceride transfer protein (MTP), exhibiting an IC50 value of 2.0 nM against both human and rodent MTP. This compound effectively reduces plasma levels of cholesterol and triglycerides when administered in vivo.
T13418	CP-319340(free base)	Others	Others
	CP-319340 free base is a inhibitor of microsomal triglyceride transfer protein (MTP) .
T15570	Implitapide 英普他派,AEGR 427	CETP	Metabolism
	Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).
T74089	Mifamurtide TFA
	Mifamurtide TFA (MTP-PE TFA) 是穆拉基二肽 (MDP) 的类似物，一种非特异性免疫调节剂，通过刺激激活巨噬细胞和单核细胞的免疫应答而发挥作用。Mifamurtide TFA 是一种孤儿药，是 NOD2的特异性配体，用作胰岛素增敏剂。Mifamurtide TFA 具有用于骨肉瘤研究的潜力。
T68588	CP-10447
	CP-10447 is an inhibitor apolipoprotein B (apoB) and triglyceride secretion in human hepatoma cells (HepG2) by inhibiting MTP activity and stimulating the early ER degradation of apoB. It is useful tool for further study of the mechanisms of apoB secretion and triglyceride-rich lipoprotein assembly.

化合物

Cat.No: T79602

Target: Autophagy

MTP 131 acetate

Cat.No: T35689

Target: Others

Cat.No: TP1095

Synonym: MTP-131,RX-31,SS-31

Target: Others

Elamipretide 2TFA

Cat.No: T8831

Synonym: MTP-131 2TFA,RX-31 2TFA,SS-31,MTP-131,SS-31 2TFA,Bendavia

Target: Others

Cat.No: T12037

Synonym: L-MTP-PE,MTP-PE,CGP 19835,米伐木肽

Target: Others

Mifamurtide sodium hydrate

Cat.No: TP2332

Synonym: L-MTP-PE,Mifamurtide,Muramyl tripeptide

Elamipretide TFA

Cat.No: TP1096

Synonym: SS-31 (TFA),MTP-131 (TFA),RX-31 (TFA)

Target: Others

Elamipretide acetate

Cat.No: TP1095L

Synonym: MTP 131 acetate,Elamipretide acetate (736992-21-5 Free base)

Mifamurtide sodium

Cat.No: TP2332L

Synonym: Muramyl tripeptide,CGP 19835A,L-MTP-PE,米伐木肽钠盐,Mepact,Junovan

Cat.No: T27719

Synonym: SLx 4090,SLx4090,KD026,SLx-4090

Target: CETP

Cat.No: T13784

Synonym: M 5011

Target: Others

Cat.No: T23033

Target: Others

Cat.No: T27601

Synonym: SID-3712502,SID 3712502,SID3712502

Cat.No: T30506

Synonym: UNII-0Z473OO6GB,BMS212122,BMS 212122

Target: CETP

Cat.No: T6267

Synonym: AEGR-733,洛美他派,BMS-201038

Target: CETP

Cat.No: T31992

Target: CETP

Cat.No: T15006

Synonym: CP742033,Slentrol

Target: Others, CETP

Lomitapide Mesylate

Cat.No: T2545

Synonym: 甲磺酸洛美他派,BMS-201038 mesylate,AEGR-733 mesylate

Target: CETP

CP-346086 dihydrate

Cat.No: T38666

Implitapide Racemate

Cat.No: T10504

Target: Others

Cat.No: T16158

Target: Adenosine Receptor

Cat.No: T39303

CP-319340(free base)

Cat.No: T13418

Target: Others

Cat.No: T15570

Synonym: 英普他派,AEGR 427

Target: CETP

Mifamurtide TFA

Cat.No: T74089

Cat.No: T68588

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