首页工具

登录

搜索结果

Search Results for " mk5 "

Targets Recommended: Kinesin

4

抑制剂 & 化合物

3

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T29059	UMK57 UMK 57,UMK-57	Kinesin	Cytoskeletal Signaling
	UMK57 是一种CENP-Ei、MCAK 增强剂，选择性促进 k-MT 附着错误纠正以抑制染色体错误分离的小分子化合物，可以通过破坏有丝分裂过程中动粒微管 (k-MT) 附着的稳定性来提高染色体分离保守性。
T12058	MK2-IN-3 hydrate MK-2 Inhibitor III	ERK; MAPK; MNK	MAPK
	MK2-IN-3 hydrate (MK-2 Inhibitor III) 是一种口服有活性的、ATP 竞争性的MAPKAP-K2 (MK-2)选择性抑制剂(IC50:0.85 nM)。
T9034	MK2-IN-3 MK2 Inhibitor III	MAPK	MAPK
	MK2-IN-3 (MK2 Inhibitor III) 是选择性的 MAPKAP-K2 (MK-2)抑制剂(IC50:8.5 nM)，能够抑制 U937 细胞及体内 TNFα 的生成。
T38653	HG-7-85-01
	HG-7-85-01 is a type II ATP competitive inhibitor targeting wild-type and gatekeeper mutations forms of Bcr-Abl, PDGFRα, Kit, and Src kinases. It effectively inhibits T315I mutant Bcr-Abl kinase, as well as KDR and RET kinases with IC50 values of 3 nM, 20 nM, and 30 nM, respectively. In contrast, HG-7-85-01 exhibits weak or no inhibition towards other kinases (IC50 >2 μM). Furthermore, this compound inhibits cell proliferation through the induction of apoptosis and by impeding cell-cycle progres...

化合物

Cat.No: T29059

Synonym: UMK 57,UMK-57

Target: Kinesin

MK2-IN-3 hydrate

Cat.No: T12058

Synonym: MK-2 Inhibitor III

Target: ERK, MAPK, MNK

Cat.No: T9034

Synonym: MK2 Inhibitor III

Target: MAPK

Cat.No: T38653

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00696	PRAK/MAPKAPK5 Protein, Human, Recombinant (Strep-II) MAPKAPK5,MK5,MAPKAP-K5,<...	Human	Baculovirus Insect Cells
	The p38 mitogen-activated protein kinase (MAPK) pathway plays an important role in cellular responses to inflammatory stimuli and environmental stress. p38 regulated/activated protein kinase (PRAK, also known as mitogen-activated protein kinase activated protein kinase 5 [MAPKAPK5]) functions downstream of p38alpha and p38beta in mediating the signaling of the p38 pathway.
TMPY-04425	PRAK/MAPKAPK5 Protein, Human, Recombinant (His & GST) PRAK,MAPKAP-K5,MK-5,mitogen-activ...	Human	Baculovirus Insect Cells
	MAPKAPK5 contains 1 protein kinase domain and belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family. MAPKAPK5 has significant sequence homology to mitogen-activated protein kinase (MAPK)-activated protein kinase (MAPKAPK). It is widely distributed. MAPKAPK5 can be phosphorylated by an extracellular-regulated kinase (ERK), and p38 kinase but not by c-jun N-terminal kinase (JNK)in vitro. Recombinant GST-MAPKAPK5 protein can phosphorylate a peptide derived from the regulator...
TMPY-04397	PAK-3 Protein, Human, Recombinant (His) PAK3β,hPAK3,bPAK,PAK3beta,MRX30,MRX47,CDKN1A,p21 protein (Cd...	Human	Baculovirus Insect Cells
	PAK3 is a member of PAK proteins, a family of serine/threonine p21-activating kinases, serve as effectors of small Rho GTPases Cdc42 and RAC and have been implicated in a wide range of biological activities. There are six mammalian PAKs which can be divided into two groups: group I PAKs (PAK1-3) and group II PAKs (PAK4-6). Although the two PAK groups are architecturally similar there are differences in their mode of regulation suggesting their cellular functions are likely to be different. Group...

重组蛋白

PRAK/MAPKAPK5 Protein, Human, Recombinant (Strep-II)

Cat.No: TMPK-00696

Species: Human

Expression System: Baculovirus Insect Cells

PRAK/MAPKAPK5 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04425

Species: Human

Expression System: Baculovirus Insect Cells

PAK-3 Protein, Human, Recombinant (His)

Cat.No: TMPY-04397

Species: Human

Expression System: Baculovirus Insect Cells

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼