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Search Results for " leu1 "

Targets Recommended: OX Receptor

18

抑制剂 & 化合物

8

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP1975L	[Ala11,D-Leu15]-Orexin B acetate [Ala11,D-Leu15]-Orexin B acetate (532932-99-3 Free base)	OX Receptor	GPCR/G Protein; Neuroscience
	[Ala11,D-Leu15]-Orexin B acetate 是一种特异性 orexin-2 受体 (OX2) 激动剂，EC50 为 0.13 nM，比 OX1 (52 nM) 特异性高 400 倍。
TP1916L1	[D-Phe12,Leu14]-Bombesin acetate [D-Phe12,Leu14]-Bombesin acetate(108437-88-3 Free base)	Bombesin Receptor	GPCR/G Protein
	[D-Phe12,Leu14]-Bombesin acetate 抑制铃蟾素刺激的分泌。
TP2103L	[D-p-Cl-Phe6,Leu17]-VIP acetate	Others	Others
	[D-p-Cl-Phe6,Leu17]-VIP acetate 是一种竞争性和选择性的血管活性肠肽 (VIP) 受体拮抗剂 (IC50 = 125.8 nM)。
TP1931L1	[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate(96736-12-8 free base)	cholecystokinin	GPCR/G Protein
	[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate ([D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate (96736-12-8 free base)) 是广谱神经肽反向激动剂和拮抗剂。 ghrelin 受体的强效完全反向激动剂(EC50 = 5.2 nM)；减少组成型生长素释放肽受体信号传导。它也是速激肽、缓激肽、CCK 和铃蟾肽受体的拮抗剂。在体外诱导细胞凋亡并抑制癌细胞生长。
T8761L	[Leu15]-Gastrin I human acetate(39024-57-2 Free base)
	[Leu15]-Gastrin I human acetate(39024-57-2 Free base) 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T8761L。
T78003	[D-p-Cl-Phe6,Leu17]-VIP TFA
	[D-p-Cl-Phe6,Leu17]-VIP TFA，为竞争性及选择性血管活性肠肽(VIP)受体拮抗剂，其IC50为125.8 nM。该化合物针对胰高血糖素、促胰液素和GRF受体均不表现活性。
T76445	(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P
	(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P 是神经肽 Substance P 的拮抗剂。
TP1975	[Ala11,D-Leu15]-Orexin B(human) [Ala11,D-Leu15]-Orexin B
	Highly potent and selective OX2 receptor agonist; displays 400-fold selectivity over OX1 receptors. EC50 values are 0.13 and 52 nM for human OX2 and OX1 receptors respectively.
T76586	(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat)
	(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) 是一种有效的 PTH-1R 拮抗剂。
T83510	[Arg-15,20,21,Leu17]-PACAP-Gly-Lys-Arg-NH2 BM-PACAP
	[Arg-15,-20,-21,Leu17]-PACAP-Gly-Lys-Arg-NH2 (BM-PACAP) 为合成PACAP 1-27 类似物，展现出明显的松弛效应。
TP1916	[D-Phe12,Leu14]-Bombesin
	Bombesin receptor antagonist that inhibits bombesin binding to rat brain with an IC50 value of 2 μM. Inhibits amylase release in vitro (IC50 = 4 μM) and attenuates bombesin-mediated suppression of food intake in vivo.
T8761	[Leu15]-Gastrin I human Amino Acid Sequence Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp-Phe-NH2	Others	Others
	[Leu15]-Gastrin I human (Amino Acid Sequence Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp-Phe-NH2) 基因编码人体内的蛋白质 [Leu15]-胃泌素 I。在人类染色体中，GAST 基因定位于 17q21.2。胃窦中的 G 细胞产生 [Leu15]-胃泌素 I 的前体前胃泌素。前胃泌素经过裂解和加工产生胃泌素，它对整个胃肠道上皮细胞具有营养作用。胃泌素对消化系统的生长至关重要，并刺激壁细胞产生胃酸。胃泌素通过称为胆囊收缩素(CCK) 或 CCK-B 受体 (CCK-BR) 的 G 蛋白偶联受体发挥其功能。胃泌素的释放受到食物的刺激，尤其是蛋白质饮食，并受到非常低的 pH 值的抑制。萎缩性胃炎、幽门螺杆菌感染和长期服用质子泵抑制剂感染可能导致胃泌素过度表达。胃腺癌显示高水平的胃泌素。
T78563	[Leu13]-Motilin KW-5139	Motilin Receptor	GPCR/G Protein
	[Leu13]-Motilin (KW-5139) 为motilin类似物，能够刺激家兔胃肠运动，并在体外以浓度依赖性方式引起胃窦、十二指肠、空肠、回肠以及降结肠的收缩。
T83690	[Leu144, Arg147]-PLP (139-151) TFA [Leu144, Arg147] Proteolipid Peptide (139-151),H-His-Ser-Leu-Gly-Lys-Leu-Leu-Gly-Arg-Pro-Asp-Lys-Phe-OH
	[Leu144,Arg147]-PLP (139-151)是髓鞘脂蛋白(PLP)的一种突变肽段，包含位于144和147位置的色氨酸到亮氨酸以及组氨酸到精氨酸的替换。使用[Leu144, Arg147]-PLP (139-151)（50 µg）乳化于完全弗氏佐剂(CFA)免疫后，能增加小鼠脾脏中的IL-4水平。它在体外抑制Th1细胞激活，但在体内不抑制，其中它诱导调节性T细胞的产生。用[Leu144, Arg147]-PLP (139-151)预免疫可以延迟由脑炎肽PLP (178-191)、髓磷脂少突细胞蛋白(MOG) (92-106)或髓鞘基础蛋白(MBP)在小鼠中诱导的实验性自身免疫性脑炎(EAE)的发病。
TP2103	[D-p-Cl-Phe6,Leu17]-VIP
	Selective vasoactive intestinal peptide (VIP) receptor antagonist (IC50 = 125.8 nM). Displays no activity on glucagon, secretin or GRF receptors.
T75921	[Ala11,D-Leu15]-Orexin B(human) TFA
	[Ala11,D-Leu15]-Orexin B(human) TFA为高效的orexin-2 receptor (OX2)选择性激动剂。其对OX2展现出比OX1 (52 nM) 高达400倍的较高选择性(EC50=0.13 nM)。
TP1931	[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P
	Broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM); diminishes constitutive ghrelin receptor signaling. Also antagonist at tachykinin, bradykinin, CCK and bombesin receptors. In
T83548	(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P acetate
	'(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P (acetate)' 是一种对 Substance P 及 Bombesin 担任拮抗作用的化合物，能针对眼部三叉神经反向刺激引起的炎症反应产生效果。

化合物

[Ala11,D-Leu15]-Orexin B acetate

Cat.No: TP1975L

Synonym: [Ala11,D-Leu15]-Orexin B acetate (532932-99-3 Free base)

Target: OX Receptor

[D-Phe12,Leu14]-Bombesin acetate

Cat.No: TP1916L1

Synonym: [D-Phe12,Leu14]-Bombesin acetate(108437-88-3 Free base)

Target: Bombesin Receptor

[D-p-Cl-Phe6,Leu17]-VIP acetate

Cat.No: TP2103L

Target: Others

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate

Cat.No: TP1931L1

Synonym: [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate(96736-12-8 free base)

Target: cholecystokinin

[Leu15]-Gastrin I human acetate(39024-57-2 Free base)

Cat.No: T8761L

[D-p-Cl-Phe6,Leu17]-VIP TFA

Cat.No: T78003

(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P

Cat.No: T76445

[Ala11,D-Leu15]-Orexin B(human)

Cat.No: TP1975

Synonym: [Ala11,D-Leu15]-Orexin B

(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat)

Cat.No: T76586

[Arg-15,20,21,Leu17]-PACAP-Gly-Lys-Arg-NH2

Cat.No: T83510

Synonym: BM-PACAP

[D-Phe12,Leu14]-Bombesin

Cat.No: TP1916

[Leu15]-Gastrin I human

Cat.No: T8761

Synonym: Amino Acid Sequence Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp-Phe-NH2

Target: Others

[Leu13]-Motilin

Cat.No: T78563

Synonym: KW-5139

Target: Motilin Receptor

[Leu144, Arg147]-PLP (139-151) TFA

Cat.No: T83690

Synonym: [Leu144, Arg147] Proteolipid Peptide (139-151),H-His-Ser-Leu-Gly-Lys-Leu-Leu-Gly-Arg-Pro-Asp-Lys-Phe-OH

[D-p-Cl-Phe6,Leu17]-VIP

Cat.No: TP2103

[Ala11,D-Leu15]-Orexin B(human) TFA

Cat.No: T75921

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P

Cat.No: TP1931

(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P acetate

Cat.No: T83548

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01235	CD5 Protein, Human, Recombinant (His) LEU1,CD5 molecule,T1	Human	HEK293 Cells
	CD5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P06127.
TMPY-05589	CD5 Protein, Human, Recombinant (His & Avi) CD5 molecule,LEU1,T1	Human	HEK293 Cells
	CD5 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 41.9 kDa and the accession number is P06127.
TMPY-05422	CD5 Protein, Human, Recombinant (hFc) CD5 molecule,LEU1,T1	Human	HEK293 Cells
	CD5 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.4 kDa and the accession number is P06127.
TMPK-00643	CD5 Protein, Rhesus macaque, Recombinant (His & Avi), Biotinylated T1,LEU1,CD5,CD5 antigen,CD5 molec...	Rhesus	HEK293 Cells
	CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma. CD5 Protein, Rhesus macaque, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.7 kDa and the accession number is F6V5Q9.
TMPK-00301	CD5 Protein, Human, Recombinant (hFc & Avi) CD5 molecule,CD5,LEU1,CD5 antigen,T1	Human	HEK293 Cells
	CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma. CD5 Protein, Human, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 67.1 kDa and the accession number is P06127.
TMPK-00642	CD5 Protein, Rhesus macaque, Recombinant (His & Avi) LEU1,T1,CD5,CD5 antigen,CD5 molec...	Rhesus	HEK293 Cells
	CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma. CD5 Protein, Rhesus macaque, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.7 kDa and the accession number is F6V5Q9.
TMPK-00302	CD5 Protein, Human, Recombinant (hFc & Avi), Biotinylated T1,LEU1,CD5 molecule,CD5 antigen,...	Human	HEK293 Cells
	CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma. CD5 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 67.1 kDa and the accession number is P06127.
TMPK-00300	CD5 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated T1,CD5,LEU1,CD5 antigen,CD5 molec...	Mouse	HEK293 Cells
	CD5: a type I transmembrane protein found on T cells, thymocytes, and some B cells that is a ligand for CD72 and is involved in cellular activation or adhesion; expressed in B-cell chronic lymphocytic leukemia and T-cell lymphoma. CD5 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 38.9 kDa and the accession number is P13379.

重组蛋白

CD5 Protein, Human, Recombinant (His)

Cat.No: TMPY-01235

Species: Human

Expression System: HEK293 Cells

CD5 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPY-05589

Species: Human

Expression System: HEK293 Cells

CD5 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05422

Species: Human

Expression System: HEK293 Cells

CD5 Protein, Rhesus macaque, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00643

Species: Rhesus

Expression System: HEK293 Cells

CD5 Protein, Human, Recombinant (hFc & Avi)

Cat.No: TMPK-00301

Species: Human

Expression System: HEK293 Cells

CD5 Protein, Rhesus macaque, Recombinant (His & Avi)

Cat.No: TMPK-00642

Species: Rhesus

Expression System: HEK293 Cells

CD5 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPK-00302

Species: Human

Expression System: HEK293 Cells

CD5 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated

Cat.No: TMPK-00300

Species: Mouse

Expression System: HEK293 Cells

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