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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T25629	LAQ 824 LAQ824,LAQ-824
	LAQ 824 is an inhibitor of histone deacetylase.
T6561	Laquinimod LAQ,ABR-215062,拉喹莫德	Apoptosis; Others; NF-κB	Apoptosis; NF-κB; Others
	Laquinimod (LAQ) 是一种免疫调节剂，可预防中枢神经系统的神经变性和炎症。
T2454	Dacinostat NVP-LAQ824,达西司特,LAQ824	HDAC; Autophagy	Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Dacinostat (NVP-LAQ824) 是一种新型 HDAC 抑制剂，IC50 为 32 nM，是 p21 启动子的激活剂。它也可抑制HDAC1的活性，IC50值为 9 nM，主要用于癌症研究。
T37695	NMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQ
	NMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQ, an ACE2-related peptide, serves as a valuable research tool for comprehending ACE2 functions.
T2779	Olaquindox
	Olaquindox 可用于生命科学领域的相关研究。其产品编号为 T2779，CAS号为 23696-28-8。
T30612	Bulaquine
	Bulaquine is a derivative of 8-aminoquinoline and has effective activity against the liver stage of plasmodium falciparum and the dormant bodies of Plasmodium vivax and Plasmodium ovale.
T61607	Laquinimod sodium
	Laquinimod (ABR-215062) sodium 是一种可口服的羧酰胺衍生物，是一种有效的免疫调节剂，可防止中枢神经系统的神经变性和炎症。Laquinimod sodium 减少星形胶质细胞NF-κB 的活化以防止铜酮 (Cuprizone) 诱导的脱髓鞘。Laquinimod sodium 具有用于多发性硬化症 (MS；RRMS 或 CPMS) 的复发缓解 (RR) 和慢性进行性 (CP) 形式以及神经退行性疾病研究的潜力。

化合物

LAQ 824

Cat.No: T25629

Synonym: LAQ824,LAQ-824

Target:

Laquinimod

Cat.No: T6561

Synonym: LAQ,ABR-215062,拉喹莫德

Target: Apoptosis, Others, NF-κB

Dacinostat

Cat.No: T2454

Synonym: NVP-LAQ824,达西司特,LAQ824

Target: HDAC, Autophagy

NMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQ

Cat. No.	Product Name	Target	Signaling Pathways
TMA0033	5'-Demethylaquillochin	NADPH-oxidase	Immunology/Inflammation
	5'-Demethylaquillochin and its isomer from the dichloromethane extract of E. cavaleriei have potential as chemopreventive agents through induction of detoxification enzymes. 5'-Demethylaquillochin exhibits the most potential chemopreventive ability.