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5

抑制剂 & 化合物

9

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T19389	L-Ascorbic acid 2-phosphate magnesium 2-Phospho-L-ascorbic acid magnesium,维生素C磷酸酯镁,维生素 C 磷酸酯镁	Phosphatase; Phosphorylase	Metabolism
	L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) 是长效的维生素 C 衍生物，能够以刺激胶原蛋白的表达和形成。它提高成骨细胞分化过程中 hASC 中的碱性磷酸酶特性和 runx2A 的表达。它能够以作为培养基补充人脂肪干细胞的成骨分化。
T8172	2-O-α-D-Glucopyranosyl-L-ascorbic Acid ASCORBYL GLUCOSIDE,抗坏血酸葡糖苷	Others	Others
	2-O-α-D-Glucopyranosyl-L-ascorbic Acid (ASCORBYL GLUCOSIDE) 是一种抗坏血酸的葡萄糖苷衍生物，可以被酶水解成为抗坏血酸，能够表现出抗癌活性。
T0752	Ascorbyl palmitate L-抗坏血酸棕榈酸酯,L-Ascorbic acid 6-hexadecanoate,6-O-Palmitoyl-L-ascorbic acid,L-Ascorbyl 6-palmitate,抗坏血酸棕榈酸酯	Reactive Oxygen Species; Endogenous Metabolite	Immunology/Inflammation; Metabolism; NF-κB
	Ascorbyl palmitate (L-Ascorbic acid 6-hexadecanoate) 是由抗坏血酸和棕榈酸形成的一种酯，一种脂溶性形式的维生素 C。
T19390	L-Ascorbic acid 2-phosphate 维生素C磷酸酯,2-Phospho-L-ascorbic acid	Others	Others
	L-ascorbic acid 2-phosphate can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation. L-ascorbic acid 2-phosphate is a long-acting vitamin C derivative that can stimulate collagen formation and expression.
T30154	Ascorbyl myristate Ascorbyl monomyristate,6-tetradecanoate,L-Ascorbic acid
	Ascorbyl myristate is a bioactive chemical.

化合物

L-Ascorbic acid 2-phosphate magnesium

Cat.No: T19389

Synonym: 2-Phospho-L-ascorbic acid magnesium,维生素C磷酸酯镁,维生素 C 磷酸酯镁

Target: Phosphatase, Phosphorylase

2-O-α-D-Glucopyranosyl-L-ascorbic Acid

Cat.No: T8172

Synonym: ASCORBYL GLUCOSIDE,抗坏血酸葡糖苷

Target: Others

Ascorbyl palmitate

Cat.No: T0752

Synonym: L-抗坏血酸棕榈酸酯,L-Ascorbic acid 6-hexadecanoate,6-O-Palmitoyl-L-ascorbic acid,L-Ascorbyl 6-palmitate,抗坏血酸棕榈酸酯

Target: Reactive Oxygen Species, Endogenous Metabolite

L-Ascorbic acid 2-phosphate

Cat.No: T19390

Synonym: 维生素C磷酸酯,2-Phospho-L-ascorbic acid

Target: Others

Ascorbyl myristate

Cat.No: T30154

Synonym: Ascorbyl monomyristate,6-tetradecanoate,L-Ascorbic acid

Cat. No.	Product Name	Target	Signaling Pathways
T0928	L-Ascorbic acid 维生素C,Vitamin C,Ascorbic acid,L(+)-Ascorbic acid,抗坏血酸,L-Ascorbate	Apoptosis; Calcium Channel; Reactive Oxygen Species; Endogenous Metabolite	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; NF-κB
	L-Ascorbic acid (Vitamin C) 属于天然产物，是一种强效的还原剂和抗氧化剂。L-Ascorbic acid 具有抗细菌感染、解毒反应和胶原蛋白形成的作用。L-Ascorbic acid 被用于治疗坏血病。
T7966	3-O-Ethyl-L-ascorbic acid	Tyrosinase	Proteases/Proteasome
	3-O-Ethyl-L-ascorbic acid 是一种具有增白能力的化妆品酪氨酸酶 (tyrosinase) 抑制剂，是一种稳定的维生素 C 衍生物。它还具有抗氧化能力。
T6674	L-Ascorbic acid sodium salt (+)-Sodium L-ascorbate,Vitamin C sodium salt,Sodium ascorbate,L-Ascorbic acid sodium,抗坏血酸钠,Sodium L-ascorbate,维生素C钠	Apoptosis; Others; Calcium Channel; Reactive Oxygen Species; Endogenous Metabolite	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; NF-κB; Others
	L-Ascorbic acid sodium salt (Vitamin C sodium salt) 是一种电子供体，是一种内源性抗氧化剂。它还是一种胶原沉积促进剂和弹性生成抑制剂。它选择性抑制 Cav3.2 通道(Cav3.2 channels)，IC50为 6.5 μM。
T2185	L-Ascorbic acid 2-phosphate trisodium L-抗坏血酸-2-磷酸三钠盐（维生素C）,L-Ascorbic acid 2-phosphate trisodium salt,Sodium L-ascorbyl-2-phosphate,Sodium ascorbyl phosphate,2-Phospho-L-ascorbic acid trisodium salt,Sodium ascorbyl monophosphate,L-抗坏血酸-2-磷酸三钠盐	Reactive Oxygen Species; c-Met/HGFR; Endogenous Metabolite	Immunology/Inflammation; Metabolism; NF-κB; Tyrosine Kinase/Adaptors
	L-Ascorbic acid 2-phosphate trisodium (Sodium ascorbyl phosphate) 是长效的维生素 C 衍生物，能够刺激胶原蛋白的表达和形成。Sodium L-ascorbyl-2-phosphate 提高成骨细胞分化过程中 hASC 中的碱性磷酸酶活性和 runx2A 的表达，因此，能够促进人脂肪干细胞的成骨分化。
T83876	L-Ascorbic Acid 6-stearate L-Ascorbyl-6-stearate,6-O-Stearoyl-L-Ascorbic Acid
	L-抗坏血酸6硬脂酸酯是L-抗坏血酸与硬脂酸的衍生物，在K. coccinea中发现，具有抗氧化和抗癌作用。在细胞外试验中清除DPPH（IC50 = 3.31 µg/ml）。包裹L-抗坏血酸6硬脂酸酯的脂质纳米颗粒（LNPs）在190 µM浓度下诱导HL-60前髓母细胞凋亡。含有L-抗坏血酸6硬脂酸酯的配方已用于化妆品和个人护理产品中。
T10077	2-O-β-D-Glucopyranosyl-L-ascorbic acid AA-2βG,抗坏血酸葡糖苷	Others	Others
	2-O-β-D-Glucopyranosyl-L-ascorbic acid (AA-2βG) is isolated from Lycium Fruit. It is a stable vitamin C analog with anti-tumor activity.
T4719	1,4-D-Gulonolactone D-Gulonic acid γ-lactone,D-(-)-古洛糖酸-1,4-内酯	Others; Endogenous Metabolite	Metabolism; Others
	1,4-D-Gulonolactone (D-Gulonic acid γ-lactone) (也称为还原性抗坏血酸，RAA) 是 L-gulono-1,4-lactone oxidoreductase (EC 1.1.3.8)的底物，催化植物和动物中l -抗坏血酸(维生素C)生物合成的最后一步。enzyme L-Gulono-1,4-lactone oxidase 在容易患坏血病、缺乏维生素c的动物(如人类)中缺失。1,4-D-Gulonolactone 存在于人体血液中，并被用作比较运动引起的氧化应激变化的标志物之一。
T5216	Calcium L-Threonate L-苏糖酸钙,L-Threonic acid Calcium Salt	Others; Endogenous Metabolite	Metabolism; Others
	Calcium L-Threonate (L-Threonic acid Calcium Saltr) 是一种抗骨质疏松症，能够刺激抗坏血酸的吸收，常用于钙补充剂。
T4917	Dehydroascorbic acid (L)-Dehydroascorbic acid,脱氢抗坏血酸,去氢抗坏血酸	Endogenous Metabolite	Metabolism
	Dehydroascorbic acid ((L)-Dehydroascorbic acid) 是维生素 C 的氧化型，能够透过血脑屏障，对中风具有有效的脑保护作用。

天然产物

L-Ascorbic acid

Cat.No: T0928

Synonym: 维生素C,Vitamin C,Ascorbic acid,L(+)-Ascorbic acid,抗坏血酸,L-Ascorbate

Target: Apoptosis, Calcium Channel, Reactive Oxygen Species, Endogenous Metabolite

3-O-Ethyl-L-ascorbic acid

Cat.No: T7966

Target: Tyrosinase

L-Ascorbic acid sodium salt

Cat.No: T6674

Synonym: (+)-Sodium L-ascorbate,Vitamin C sodium salt,Sodium ascorbate,L-Ascorbic acid sodium,抗坏血酸钠,Sodium L-ascorbate,维生素C钠

Target: Apoptosis, Others, Calcium Channel, Reactive Oxygen Species, Endogenous Metabolite

L-Ascorbic acid 2-phosphate trisodium

Cat.No: T2185

Synonym: L-抗坏血酸-2-磷酸三钠盐（维生素C）,L-Ascorbic acid 2-phosphate trisodium salt,Sodium L-ascorbyl-2-phosphate,Sodium ascorbyl phosphate,2-Phospho-L-ascorbic acid trisodium salt,Sodium ascorbyl monophosphate,L-抗坏血酸-2-磷酸三钠盐

Target: Reactive Oxygen Species, c-Met/HGFR, Endogenous Metabolite

L-Ascorbic Acid 6-stearate

Cat.No: T83876

Synonym: L-Ascorbyl-6-stearate,6-O-Stearoyl-L-Ascorbic Acid

2-O-β-D-Glucopyranosyl-L-ascorbic acid

Cat.No: T10077

Synonym: AA-2βG,抗坏血酸葡糖苷

Target: Others

1,4-D-Gulonolactone

Cat.No: T4719

Synonym: D-Gulonic acid γ-lactone,D-(-)-古洛糖酸-1,4-内酯

Target: Others, Endogenous Metabolite

Calcium L-Threonate

Cat.No: T5216

Synonym: L-苏糖酸钙,L-Threonic acid Calcium Salt

Target: Others, Endogenous Metabolite

Dehydroascorbic acid

Cat.No: T4917

Synonym: (L)-Dehydroascorbic acid,脱氢抗坏血酸,去氢抗坏血酸

Target: Endogenous Metabolite

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