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Cat. No.	Product Name	Target	Signaling Pathways
T25487	Haloperidol decanoate KD 16,KD-136,KD 136,Neoperidole,Haldol	Others	Others
	Haloperidol decanoate (KD 16) 是一种典型的抗精神病药物，用作精神分裂症和情绪障碍的维持治疗，配制成用于肌肉注射的酯。
T6305	SNX2112 SNX-2112,PF 04928473,SNX 2112	HSP	Cytoskeletal Signaling; Metabolism
	SNX2112 (PF 04928473) 是一种具有口服活性的 Hsp90 抑制剂，Kd 为 16 nM。
TP1380	Galanin (1-16), mouse, porcine, rat	Neuropeptide Y Receptor	GPCR/G Protein; Neuroscience
	Galanin (1-16), mouse, porcine, rat 是一种有效的甘丙肽受体激动剂，Kd 为 3 nM。
T16334	NMS-P515	Others	Others
	NMS-P515 is an effective, orally active, and stereospecific PARP-1 inhibitor (Kd: 16 nM and an IC50: 27 nM (in Hela cells)). It has anti-tumor activity.
TP1317	Galanin (1-16), mouse, porcine, rat TFA
	Galanin (1-16), mouse, porcine, rat is an agonist of the hippocampal galanin receptor, with a Kd of 3 nM. Galanin (1-16), mouse, porcine, rat shows high biological activity on locus coeruleus neurons.
T60556	SARS-CoV-2-IN-16
	SARS-CoV-2-IN-16 (Compound 12) 是SARS-CoV-2核衣壳蛋白的有效抑制剂，具有强效的抗病毒活性(EC50 = 3.69 μM)。SARS-CoV-2-IN-16 以7.82 μM 的低Kd 值与 NPro 结合，这表明 SARS-CoV-2-IN-16 是一种有效的 NPro 配体。
T60251	GID4 Ligand 3
	GID4 Ligand 3 (compound 16) 是GID4的结合物，体外Kd 值为 110 μM，IC50值为 148.5 μM。GID4 Ligand 3 可用于 cereblon(CRBN) 和Von Hippel-Lindau(VHL)的相关研究。
T61613	SARS-CoV-2-IN-17
	SARS-CoV-2-IN-17 (Compound 16) is a highly effective inhibitor of SARS-CoV-2 nucleocapsid protein (NPro). It demonstrates potent anti-viral activity, with an EC50 value of 2.18 μM. Furthermore, SARS-CoV-2-IN-17 binds to NPro with a low Kd value of 7.82 μM, highlighting its potency as a NPro ligand [1].
T77148	Pegdinetanib
	Pegdinetanib (BMS-844203; CT-322) 是一种选择性 VEGFR-2(VEGFR) 抑制剂，对人和鼠 VEGFR-2 的 Kd 分别为 11 nM 和 250 nM，IC50分别为 16 nM 和 240 nM。Pegdinetanib 不与 VEGFR-1或 VEGFR-3结合。Pegdinetanib 具有抗肿瘤活性。
T36292	NSC 12
	NSC 12 is an extracellular trap for fibroblast growth factor 2 (FGF2) that binds FGF2 (Kd = 51 μM) and interferes with its interaction with FGFR1, without affecting the ability of FGF2 to bind heparin or heparin sulfate proteoglycans (HSPGs). NSC 12 also binds several other, but not all, FGF isoforms with Kd values ranging between 16 and 120 μM, preventing them from forming HSPG/FGF/FGFR ternary complexes. NSC 12 inhibits FGF-dependent angiogenesis and tumor cell proliferation in vitro and reduc...
T11896	LV-320	Cysteine Protease	Proteases/Proteasome
	LV-320 是一种有效且非竞争性的ATG4B 抑制剂，其IC50值为 24.5 μM，Kd 值为 16 μM。 LV-320 抑制ATG4B 的酶促活性，阻断细胞自噬，并且稳定无毒，在体内具有活性。
T36890	A 410099.1
	High affinity XIAP antagonist (Kd = 16 nM for the BIR3 domain of XIAP). Exhibits cytotoxicity in a wide range of cancer cell lines in vitro (EC50 = 13 nM in MDA-MB-231 cells). Also displays antitumor activity in a mouse breast cancer xenograft model. Enhances TRAIL-induced apoptosis in chronic lymphocytic leukemia (CLL) cells. Oost et al (2004) Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer. J.Med.Chem. 47 4417 PMID:15317454 \|Loeder et al (2009) A n...
T10840L	CM-579	DNA Methyltransferase; Histone Methyltransferase	Chromatin/Epigenetic
	CM-579 是首创的、可逆的，G9a 和 DNA 甲基转移酶 (DNMT) 的双抑制剂，其 IC50 值分别为 16 nM 和32 nM。在多种癌细胞中发挥有效活性作用。
T10840	CM-579 trihydrochloride (1846570-40-8 free base) CM-579 trihydrochloride	DNA Methyltransferase	Chromatin/Epigenetic
	CM-579 trihydrochloride is a first-in-class reversible and dual inhibitor of G9a and DNMT (IC50s: 16 nM, 32 nM) with potent in vitro cellular activity in a wide range of cancer cells.

化合物

Haloperidol decanoate

Cat.No: T25487

Synonym: KD 16,KD-136,KD 136,Neoperidole,Haldol

Target: Others

Cat.No: T6305

Synonym: SNX-2112,PF 04928473,SNX 2112

Target: HSP

Galanin (1-16), mouse, porcine, rat

Cat.No: TP1380

Target: Neuropeptide Y Receptor

Cat.No: T16334

Target: Others

Galanin (1-16), mouse, porcine, rat TFA

Cat.No: TP1317

SARS-CoV-2-IN-16

Cat.No: T60556

Cat.No: T60251

SARS-CoV-2-IN-17

Cat.No: T61613

Cat.No: T77148

Cat.No: T36292

Cat.No: T11896

Target: Cysteine Protease

Cat.No: T36890

Cat.No: T10840L

Target: DNA Methyltransferase, Histone Methyltransferase

CM-579 trihydrochloride (1846570-40-8 free base)

Cat.No: T10840

Synonym: CM-579 trihydrochloride

Target: DNA Methyltransferase

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