Cat. No. | Product Name | Target | Signaling Pathways |
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T1056 |
Isoprenaline hydrochloride
NCI-c55630,Isoproterenol hydrochloride,Isoprenaline HCl,盐酸异丙肾上腺素 |
PI3K; Endogenous Metabolite; Adrenergic Receptor; PDE | GPCR/G Protein; Metabolism; Neuroscience; PI3K/Akt/mTOR signaling |
Isoprenaline hydrochloride (NCI-c55630) 是非选择性的β-肾上腺素能受体激动剂,有支气管扩张剂,外周血管扩张剂和心脏刺激活性。 | |||
T69598 |
Isoproterenol-d7 HCl
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Isoproterenol-d7 is intended for use as an internal standard for the quantification of isoproterenol by GC- or LC-MS. Isoproterenol is an agonist of β1- and β2-adrenergic receptors (β1- and β2-ARs; Kis = 224 and 458 nM, respectively). It is selective for β1- and β2-ARs over β3-ARs (Ki = 1,570 nM). Isoproterenol inhibits contractions in isolated field-stimulated rat vas deferens (EC50 = 45.6 nM). In vivo, isoproterenol (0.33 mg/kg) decreases blood pressure and increases water intake in nephrectom... | |||
T26822 |
Bisaramil hydrochloride
RGH-2957,NK 1556,NK1556,Bisaramil,NK-1556,RGH 2957 |
Potassium Channel; Adrenergic Receptor | GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience |
Bisaramil hydrochloride (Bisaramil) 是一种新型二氮双环壬烷抗心律失常化合物,抑制自由基生成。Bisaramil hydrochloride 可阻断钠电流,抑制异丙肾上腺素在 K(+) 去极化肌上诱导的缓慢 Ca(2+) 动作电位。 | |||
T70854 |
Protokylol hydrochloride
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Protokylol hydrochloride is the salt form of Protokylol (free base) (Asmetil, Caytine, Palison, Ventaire), a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States. It is methylenedioxyphenyl-isoproterenol. | |||
T69324 | Clofeverine hydrochloride | ||
Clofeverine hydrochloride is the salt form of Clofeverine (free base), a highly selective relaxant for gastrointestinal smooth muscles with a beta-receptor stimulative nature. On isolated ileum, the inhibitory effect of clofeverine for spontaneous motility was comparable to that of isoproterenol and 100 times higher than that of papaverine. |