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Cat. No. | Product Name | Target | Signaling Pathways |
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T62216 |
Influenza virus-IN-5
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Influenza virus-IN-5 (Compound 5f) 是一种流感病毒血球凝集素 (hemagglutinin (HA)) 抑制剂,能够作用于 A/H3N2 病毒 (EC50: 1 nM)。 | |||
T61877 |
Influenza A virus-IN-5
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Influenza A virus-IN-5 (Compound 16e) is a highly potent and orally active agent against the influenza A virus (IAV), exhibiting an IC 50 of 1.29 μM. It effectively inhibits the transcription and replication of viral RNA while maintaining acceptable levels of cytotoxicity [1]. | |||
T72792 | trans-RdRP-IN-5 | ||
trans-RdRP-IN-5 是一种有效的流感病毒 RNA 依赖性 RNA 聚合酶 (RdRP) 抑制剂。trans-RdRP-IN-5 可用于流感病毒的研究。 | |||
T72896 | cis-RdRP-IN-5 | ||
cis-RdRP-IN-5 是一种有效的流感病毒 RNA 依赖性 RNA 聚合酶 (RdRP) 抑制剂。cis-RdRP-IN-5 可用于流感病毒的研究。 | |||
T73323 | RdRP-IN-5 | Influenza Virus | Microbiology/Virology |
RdRP-IN-5 (compound 20) 为一种抑制流感病毒RNA依赖性RNA聚合酶(RdRP)的有效药物,适用于该病毒研究。 | |||
T38118 |
Zanamivir-13C,15N2
Zanamivir-13C,15N2 |
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Zanamivir-13C,15N2is intended for use as an internal standard for the quantification of zanamivir by GC- or LC-MS. Zanamivir is a sialic acid analog that inhibits neuraminidase release of newly replicated influenza virus particles.1It has been shown to selectively inhibit the growth of influenza A and B viruses in plaque reduction assays with IC50values ranging from 5 to 14 nM and to directly inhibit influenza A and B virus neuraminidases with IC50values ranging from 0.6 to 7.9 nMin vitro. Intra... | |||
T63910 |
Cap-dependent endonuclease-IN-5
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Cap-dependent endonuclease-IN-5 是 cap-dependent 核酸内切酶 (CEN) 的有效抑制剂。Cap-dependent endonuclease-IN-5 具有很好的流感病毒抑制活性,和/或具有更低的细胞毒性、更好的体内药代动力学特性和体内药效学特性。 | |||
T36986 |
Colletodiol
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Colletodiol is a fungal metabolite that has been found inD. grovesiiand has immunosuppressant and antiviral activities.1,2It inhibits concanavalin A- or LPS-induced proliferation of isolated mouse splenocytes (IC50s = 12 and 5 μg/ml, respectively).1Colletodiol inhibits influenza A viral replication in HeLa-IAV-Luc cells.2 1.Fujimoto, H., Nagano, J., Yamaguchi, K., et al.Immunosuppressive components from an ascomycete, Diplogelasinospora grovesiChem. Pharm. Bull.46(3)423-429(1998) 2.Lai, W., Wang... | |||
T37843 |
Australine (hydrochloride)
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Australine is a pyrrolizidine alkaloid originally isolated fromC. australethat has enzyme inhibitory activities.1,2,3It is an inhibitor of glucoamylase (IC50= 5.8 μM) that also inhibits glucosidase I, sucrase, maltase, andA. nigerα-glucosidase (IC50s = 20, 28, 35, and 28 μM, respectively).2,3Australine is selective for these enzymes over glucosidase II, α- and β-mannosidase, and α- and β-galactosidase up to 500 μM, β-glucosidase, with only 5% inhibition at 66 μM, as well as isomaltase and trehal... | |||
T38297 |
Ribavirin-13C5
Ribavirin-13C5 |
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Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to an active triphosphate form that induces viral RNA chain termination and inhibits viral polymerases. It reduces replication in a panel of seven RNA and four DNA viruses in Vero cells (EC50s = 2-95 μg/ml).3Ribavirin also reduces replication of severe acute respiratory syndrome coro... |
Cat. No. | Product Name | Target | Signaling Pathways |
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T4S2126 |
Ginkgetin
银杏双黄酮,银杏素 |
Apoptosis; Wnt/beta-catenin; COX; STAT; Autophagy | Apoptosis; Autophagy; Cytoskeletal Signaling; Immunology/Inflammation; JAK/STAT signaling; Neuroscience; Stem Cells |
Ginkgetin 是从银杏叶中分离得到的一种双黄酮,具有抗肿瘤、抗炎、神经保护、抗真菌的作用。它也是 Wnt 信号抑制剂,IC50值为 5.92 μM。 |